Search Results - "VOORN, Daphne A"

Prognostic Role of Thymidylate Synthase, Thymidine Phosphorylase/ Platelet-derived Endothelial Cell Growth Factor, and Proliferation Markers in Colorectal Cancer by van Triest, B, Pinedo, H M, Blaauwgeers, J L, van Diest, P J, Schoenmakers, P S, Voorn, D A, Smid, K, Hoekman, K, Hoitsma, H F, Peters, G J

“…5-Fluorouracil (5FU)-based therapy is given to patients with advanced colorectal cancer and as adjuvant treatment. Thymidylate synthase (TS) is the target for…”
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Gemcitabine and Paclitaxel: Pharmacokinetic and Pharmacodynamic Interactions in Patients With Non–Small-Cell Lung Cancer by KROEP, J. R, GIACCONE, G, PETERS, G. J, VOORN, D. A, SMIT, E. F, BEIJNEN, J. H, ROSING, H, VAN MOORSEL, C. J. A, VAN GROENINGEN, C. J, POSTMUS, P. E, PINEDO, H. M

“…To assess possible pharmacokinetic and pharmacodynamic interactions between gemcitabine and paclitaxel in a phase I/II study in non-small-cell lung cancer…”
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Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors by VAN DER WILT, Clasina L, BACKUS, Harold H. J, JACKMAN, Ann L, JANSEN, Gerrit, PETERS, Godefridus J, SMID, Kees, COMIJN, Lizzy, VEERMAN, Gijsbert, WOUTERS, Dorine, VOORN, Daphne A, PRIEST, David G, BUNNI, Marlene A, MITCHELL, Fraser

“…Plasma levels of folates and thymidine in mice are about 10-fold higher than in humans and may influence the therapeutic efficacy of thymidylate synthase (TS)…”
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Differential effects of gemcitabine on ribonucleotide pools of twenty-one solid tumour and leukaemia cell lines by van Moorsel, Catharina J.A, Bergman, Andries M, Veerman, Gijsbert, Voorn, Daphne A, Ruiz van Haperen, Veronique W.T, Kroep, Judith R, Pinedo, Herbert M, Peters, Godefridus J

“…To gain a more detailed insight into the metabolism of 2′,2′-difluoro-2′-deoxycytidine (dFdC, gemcitabine, Gemzar) and its effect on normal ribonucleotide…”
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Collateral sensitivity to gemcitabine (2′,2′-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines by Bergman, Andries M., Munch-Petersen, Birgitte, Jensen, Peter Buhl, Sehested, Maxwell, Veerman, Gijsbert, Voorn, Daphne A., Smid, Kees, Pinedo, Herbert M., Peters, Godefridus J.

“…Multidrug resistance (MDR), characterized by a cross-resistance to many natural toxin-related compounds, may be caused either by overexpression of a drug…”
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Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562 by Dumontet, Charles, Fabianowska‐Majewska, Krystyna, Mantincic, Danko, Callet Bauchu, Evelyne, Tigaud, Isabelle, Gandhi, Varsha, Lepoivre, Michel, Peters, Godefridus J., Rolland, Marie Odile, Wyczechowska, Dorota, Fang, Xiao, Gazzo, Sophie, Voorn, Daphne A., Vanier‐Viornery, Armelle, Mackey, John

“…Resistant variants of the human leukaemic line K562 were developed using selection with the deoxynucleoside analogues cytosine arabinoside,…”
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Collateral sensitivity to gemcitabine (2′,2′-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines11Abbreviations: ara-C,1-β-d-arabinofuranosylcytosine; dCDA, deoxycytidinedeaminase; dCK, deoxycytidine kinase; dCyd, deoxycytidine; dFdC,2′,2′-difluorodeoxycytidine; MDR, multidrug resistance; MRP,multidrug resistance-associated protein; P-gP, P-glycoprotein; SCLC,small cell lung carcinoma; TCA, trichloroacetic acid; by Bergman, Andries M., Munch-Petersen, Birgitte, Jensen, Peter Buhl, Sehested, Maxwell, Veerman, Gijsbert, Voorn, Daphne A., Smid, Kees, Pinedo, Herbert M., Peters, Godefridus J.

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Influence of ovariectomy on extracellular fluid volume in rats: Assessment of extracellular fluid volume by means of bromide by Bolscher, Marieke Dijkgraaf-ten, Barto, Rob, Voorn, Daphne A., Compas, Dirk, Netelenbos, J.Coen, van der Vijgh, Wim J.F.

“…There is considerable evidence that the extracellular fluid volume (ECV) may change in disease states or during longitudinal intervention studies. Therefore,…”
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