Search Results - "VONKA, VLADIMIR"
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Prophylactic vaccines against cancers of non-infectious origin: a dream or a real possibility?
Published in Central European journal of public health (01-12-2021)“…The dramatic progress in tumour biology and immunology in the past several years has opened new avenues for the treatment and prevention of cancer. One of the…”
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Immunology of chronic myeloid leukemia: current concepts and future goals
Published in Expert review of clinical immunology (01-04-2015)“…Although chronic myeloid leukemia is a rare malignancy, it has developed into a model system for the study of a variety of aspects of cancer biology and…”
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PROFESSOR ERVIN ADAM
Published in Central European journal of public health (01-03-2013)“…Last November, a few days after his 90th birthday, Dr. Ervin Adam, a member of the Journal Editorial Board and Professor of Epidemiology at Baylor University…”
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Immunotherapy of chronic myeloid leukemia: present state and future prospects
Published in Immunotherapy (01-03-2010)“…In spite of the considerable successes that have been achieved in the treatment of chronic myeloid leukemia (CML), cure for the disease can only be obtained by…”
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Comments on therapeutic cancer vaccines
Published in Immunotherapy (01-02-2012)Get more information
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Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony-stimulating factor: I. Derivation, genetic stability, oncogenicity and immunogenicity
Published in International journal of oncology (01-05-2012)“…The highly oncogenic bcr-abl-transformed mouse (Balb/c) 12B1 cells were transfected with plasmids carrying genes for either mouse interleukin-2 (IL‑2) or the…”
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Tumor Protective Activity of CD4+ but Not of CD8+ T Cells in DNA-Vaccinated Mice Challenged with bcr-abl-Transformed Cells
Published in Clinical & developmental immunology (01-01-2013)“…In the recent past, it has repeatedly been reported that CD4 cells play an important role in the immunology of chronic myeloid leukaemia. It was therefore of…”
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Immunisation with modified HPV16 E7 genes against mouse oncogenic TC-1 cell sublines with downregulated expression of MHC class I molecules
Published in Vaccine (07-03-2003)“…Human papillomavirus type 16 (HPV16)-transformed mouse TC-1 cells are extensively used in the evaluation of efficacy of experimental vaccines against tumours…”
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Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony stimulating factor (GM-CSF): II. Adverse effects of GM-CSF
Published in International journal of oncology (01-06-2012)“…Granulocyte-macrophage colony stimulating factor (GM-CSF) is considered to be the most effective immunostimulating factor for the construction of…”
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Predictive value of serum cytokine levels in chronic myeloid leukemia patients
Published in Immunology letters (01-11-2016)“…Highlights • Cytokine levels in CML patients at diagnosis and therapy outcome were related. • MCP-1 levels were significantly higher in patients with optimal…”
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Protein Profiling of Two Mouse BCR-ABL-Transformed Cell Lines
Published in Blood (18-11-2011)“…Abstract 4720 Our efforts aim at the development of effective experimental vaccines against bcr-abl-transformed cells. For our study two mouse (Balb/c)…”
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Unexpected properties of endostatin-producing mouse BCR-ABL-transformed cells
Published in International journal of oncology (01-02-2012)“…We investigated whether a genetic modification of BCR-ABL-transformed mouse cells that resulted in endostatin (ES) production altered their oncogenic…”
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Bcr-Abl fusion sequences do not induce immune responses in mice when administered in mouse polyomavirus based virus-like particles
Published in International journal of oncology (01-12-2009)“…Mouse polyomavirus-like particles (MPyV-VLPs) carrying inside a fragment of the Bcr-Abl hybrid protein containing the epitope of chronic myeloid leukemia…”
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Changes of Immunological Profiles in Patients with Chronic Myeloid Leukemia in the Course of Treatment
Published in Clinical & developmental immunology (01-01-2010)“…In the previous paper of ours we compared, prior to start any treatment, a number of immunological parameters in 24 chronic myeloid leukemia patients with the…”
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Human hair follicle and interfollicular keratinocyte reactivity to mouse HPV16-transformed cells : An in vitro study
Published in Oncology reports (01-07-2008)“…The role of stem cells in cancer formation and spreading has been established. As with normal tissue, the cancer stem cells need a special microenvironment to…”
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Intracellular Cytokines Produced by Stimulated CD3+ Cells from Chronic Myeloid Leukemia Patients
Published in Acta haematologica (01-01-2017)“…Our work examined the production of intracellular interferon (INF)-γ, tumor necrosis factor (TNF)-α, interleukin (IL)-2, and IL-4 by in vitro stimulated CD3+…”
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VACCINES AGAINST HUMAN PAPILLOMAVIRUSES : A MAJOR BREAKTHROUGH IN CANCER PREVENTION
Published in Central European journal of public health (01-12-2007)“…Carcinoma of the cervix (CaCer) is the second most frequent malignancy in women on a global scale. Epidemiological studies carried out at the beginning of the…”
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Causality in medicine: the case of tumours and viruses
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29-12-2000)“…Clarification of the aetiology of chronic human diseases such as atherosclerosis or cancer is one of the dominant topics in contemporary medical research. It…”
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Administration of a plasmid that expresses SDF-1α affects the oncogenic potential of mouse bcr-abl-transformed cells
Published in Molecular medicine reports (01-10-2014)“…Stromal-derived factor 1α (SDF-1α, also known as CXCL12) is a chemokine that exerts its effects through the G-protein coupled receptors, C-X-C chemokine…”
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Kynurenine and uric acid levels in chronic myeloid leukemia patients
Published in Oncoimmunology (01-03-2015)“…Indoleamine 2,3-dioxygenase 1 (IDO1), IDO2 and tryptophan 2,3-dioxygenase (TDO) represent some of the key immune regulators. Their increased activity has been…”
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