Search Results - "VON MARSCHALL, Zofia"
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Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling
Published in Biochemical and biophysical research communications (24-09-2010)“…► sFRP2 enhances the Wnt3a-induced β-catenin stabilization and its nuclear translocation. ► sFRP2 enhances LRP6 phosphorylation and Wnt3a/β-catenin…”
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Rough endoplasmic reticulum trafficking errors by different classes of mutant dentin sialophosphoprotein (DSPP) cause dominant negative effects in both dentinogenesis imperfecta and dentin dysplasia by entrapping normal DSPP
Published in Journal of bone and mineral research (01-06-2012)“…Families with nonsyndromic dentinogenesis imperfecta (DGI) and the milder, dentin dysplasia (DD), have mutations in one allele of the dentin…”
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De novo expression of vascular endothelial growth factor in human pancreatic cancer: Evidence for an autocrine mitogenic loop
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2000)“…Background & Aims: The role of vascular endothelial growth factor (VEGF) and its receptors in tumor angiogenesis has been well established. We analyzed the…”
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Targeting osteopontin suppresses glioblastoma stem‐like cell character and tumorigenicity in vivo
Published in International journal of cancer (01-09-2015)“…Osteopontin (OPN) is a secreted protein involved in most aspects of tumor progression and metastasis development. Elevated OPN expression has been reported in…”
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Dentin Matrix Protein-1 Isoforms Promote Differential Cell Attachment and Migration
Published in The Journal of biological chemistry (21-11-2008)“…Dentin matrix protein-1 (DMP1), bone sialoprotein (BSP), and osteopontin (OPN) are three SIBLINGs (small integrin-binding ligand, N-linked glycoproteins)…”
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Overexpression of pRB in Human Pancreatic Carcinoma Cells: Function in Chemotherapy-Induced Apoptosis
Published in JNCI : Journal of the National Cancer Institute (16-01-2002)“…Background: Human pancreatic adenocarcinomas are highly resistant to chemotherapy. The p16 tumor-suppressor protein is inactivated in more than 90% of human…”
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Dentin sialophosphoprotein (DSPP) is cleaved into its two natural dentin matrix products by three isoforms of bone morphogenetic protein-1 (BMP1)
Published in Matrix biology (01-05-2010)“…The protease that cleaves the most abundant non-collagenous protein of dentin matrix, dentin sialophosphoprotein (DSPP), into its two final dentin matrix…”
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Decorin is processed by three isoforms of bone morphogenetic protein-1 (BMP1)
Published in Biochemical and biophysical research communications (15-01-2010)“…The secreted small proteoglycan, decorin, modulates collagen fibril formation as well as the bioactivity of various members of the transforming growth factor-β…”
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A Novel Function for the Tumor Suppressor p16INK4a
Published in The Journal of cell biology (18-09-2000)“…The tumor suppressor gene p16INK4a inhibits the kinase activity of the cyclin-dependent kinase 4–6/cyclin D complexes and subsequent phosphorylation of…”
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Angiopoietin‐2 drives lymphatic metastasis of pancreatic cancer
Published in The FASEB journal (01-10-2011)“…ABSTRACT Lymphatic metastasis constitutes a critical route of disease dissemination, which limits the prognosis of patients with pancreatic ductal…”
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VEGF‐D promotes tumor growth and lymphatic spread in a mouse model of hepatocellular carcinoma
Published in International journal of cancer (01-06-2008)“…Lymphatic spread is an important clinical determinant for the prognosis of hepatocellular carcinoma (HCC), but little is known about the control of…”
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Efficient trafficking of acidic proteins out of the endoplasmic reticulum involves a conserved amino terminal IleProVal (IPV)-like tripeptide motif
Published in Connective tissue research (01-08-2014)“…Most of the proposed extracellular biomineralization processes include the secretion of proteins that interact with mineral ions and/or mineral surfaces…”
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Effects of Interferon Alpha on Vascular Endothelial Growth Factor Gene Transcription and Tumor Angiogenesis
Published in JNCI : Journal of the National Cancer Institute (19-03-2003)“…Background: Interferon alpha (IFN-α) has antiangiogenic activity, although the underlying mechanism of action is unclear. Because human neuroendocrine (NE)…”
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Dentin Matrix Protein-1 Isoforms Promote Differential Cell Attachment and MigrationS
Published in The Journal of biological chemistry (21-11-2008)“…Dentin matrix protein-1 (DMP1), bone sialoprotein (BSP), and osteopontin (OPN) are three SIBLINGs ( s mall i ntegrin- b inding li gand, N -linked g…”
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Rough Endoplasmic Reticulum (rER) Trafficking Errors by Different Classes of Mutant DSPP Cause the Dominant Negative Effects in both Dentinogenesis Imperfecta and Dentin Dysplasia by Entrapping Normal DSPP
Published in Journal of bone and mineral research (01-06-2012)“…Families with nonsyndromic dentinogenesis imperfecta (DGI) and the milder, dentin dysplasia (DD), have mutations in one allele of the dentin…”
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Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells
Published in Cancer research (Chicago, Ill.) (01-03-2003)“…The expression pattern and functional interaction of proangiogenic factors in human cholangiocellular carcinoma (CCC) have not been fully defined. We therefore…”
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DMP1 isoforms promote differential cell attachment and migration
Published in Matrix biology (01-12-2008)Get full text
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Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancer
Published in International journal of oncology (01-09-2005)“…The presence of lymphatic metastases is a strong indicator for poor prognosis in patients with ductal pancreatic cancer. In order to better understand the…”
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Activin a stimulates VEGF gene transcription in human hepatocellular carcinoma cells
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2003)Get full text
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