Search Results - "VON LUBITZ, D. K. J. E"

Protection against ischemic damage by adenosine amine congener, a potent and selective adenosine A 1 receptor agonist by Von Lubitz, Dag K.J.E, Lin, Rick C.-S, Bischofberger, Norbert, Beenhakker, Mark, Boyd, Mellonie, Lipartowska, Renata, Jacobson, Kenneth A

“…Although the selectivity and potency of adenosine amine congener (ADAC) at adenosine A 1 receptors are similar to other highly selective agonists at this…”
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Adenosine A3 receptor stimulation and cerebral ischemia by Von Lubitz, D K, Lin, R C, Popik, P, Carter, M F, Jacobson, K A

“…Chronic treatment with the selective adenosine A3 receptor agonist N6-(3-iodobenzyl)adenosine-5'-N-methylcarboxamide (IB-MECA) administered prior to either 10…”
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Cerebral ischemia in gerbils : effects of acute and chronic treatment with adenosine A2A receptor agonist and antagonist by VON LUBITZ, D. K. J. E, LIN, R. C. S, JACOBSON, K. A

“…Despite significant progress in understanding of the potential of adenosine A1 receptor-based therapies in treatment of cerebral ischemia and stroke, very…”
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Adenosine and cerebral ischemia: therapeutic future or death of a brave concept? by Von Lubitz, Dag K.J.E.

“…Numerous studies have consistently shown that agonist stimulation of adenosine A 1 receptors results in a significant reduction of morbidity and mortality…”
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Chronic administration of adenosine A3 receptor agonist and cerebral ischemia : neuronal and glial effects by VON LUBITZ, D. K. J. E, LIN, R. C.-S, BOYD, M, BISCHOFBERGER, N, JACOBSON, K. A

“…We have previously shown that chronic administration of the selective A3 receptor agonist N6-(3-iodobenzyl)-5'-N-methylcarboxoamidoadenosine (IB-MECA) leads to…”
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Protection against ischemic damage by adenosine amine congener, a potent and selective adenosine A1 receptor agonist by VON LUBITZ, D. K. J. E, LIN, R. C.-S, BISCHOFBERGER, N, BEENHAKKER, M, BOYD, M, LIPARTOWSKA, R, JACOBSON, K. A

“…Although the selectivity and potency of adenosine amine congener (ADAC) at adenosine A1 receptors are similar to other highly selective agonists at this…”
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The effects of adenosine A3 receptor stimulation on seizures in mice by VON LUBITZ, D. K. J. E, CARTER, M. F, DEUTSCH, S. I, LIN, R. C.-S, MASTROPAOLO, J, MESHULAM, Y, JACOBSON, K. A

“…We have previously shown that acute preischemic adenosine A3 receptor stimulation results in an increased postischemic damage, while chronic stimulation of…”
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Chronic administration of selective adenosine A1 receptor agonist or antagonist in cerebral ischemia by Von Lubitz, D K, Lin, R C, Melman, N, Ji, X D, Carter, M F, Jacobson, K A

“…The effect of chronic administration of selective adenosine A1 receptor agonists and antagonists on the outcome of cerebral ischemia is entirely unknown…”
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Effects of chronic administration of adenosine A1 receptor agonist and antagonist on spatial learning and memory by Von Lubitz, D K, Paul, I A, Bartus, R T, Jacobson, K A

“…Spatial memory acquisition in Morris water maze was tested in C57BL/6 mice. Animals were injected once daily with different doses of either…”
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Internucleosomal DNA fragmentation in gerbil hippocampus following forebrain ischemia by Sei, Y, Von Lubitz, K J, Basile, A S, Borner, M M, Lin, R C, Skolnick, P, Fossom, L H

“…Internucleosomal DNA fragmentation, the characteristics feature of programmed cell death, was demonstrated in gerbil hippocampus following 10 min of forebrain…”
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Reduction of postischemic brain damage and memory deficits following treatment with the selective adenosine A1 receptor agonist by VON LUBITZ, D. K. J. E, BEENHAKKER, M, LIN, R. C.-S, CARTER, M. F, PAUL, I. A, BISCHOFBERGER, N, JACOBSON, K. A

“…Agonists of adenosine A1 receptors have been frequently proposed as candidates for clinical development in treatment of cerebral ischemia and stroke. Numerous…”
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Chronic adenosine A1 receptor agonist and antagonist: effect on receptor density and N-methyl-D-aspartate induced seizures in mice by Von Lubitz, D K, Paul, I A, Ji, X D, Carter, M, Jacobson, K A

“…The effect of chronic administration of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) and the adenosine A1 antagonist…”
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Postischemic administration of adenosine amine congener (ADAC): analysis of recovery in gerbils by Von Lubitz, Dag K.J.E., Lin, Rick C.-S., Paul, Ian A., Beenhakker, Mark, Boyd, Mellonie, Bischofberger, Norbert, Jacobson, Kenneth A.

“…Although adenosine receptor-based treatment of cerebral ischemia and other neurodegenerative disorders has been frequently advocated, cardiovascular side…”
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Striatal outflow of adenosine, excitatory amino acids, γ-aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion : Correlations with neurological deficit and histopathological damage. Commentary by MELANI, A, PANTONI, L, CORSI, C, BIANCHI, L, MONOPOLI, A, BERTORELLI, R, PEPEU, G, PEDATA, F, VON LUBITZ, D. K. J. E

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A novel treatment of global cerebral ischaemia with a glycine partial agonist by Von Lubitz, D K, Lin, R C, McKenzie, R J, Devlin, T M, McCabe, R T, Skolnick, P

“…Chronic treatment of gerbils with 1-aminocyclopropanecarboxylic acid (a high affinity, partial agonist at strychnine-insensitive glycine receptors) resulted in…”
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Adenosine A3 receptor agonist-induced neurotoxicity in rat cerebellar granule neurons by Sei, Yoshitatsu, Lubitz, Dag K.J.E. von, Abbracchio, Maria P., Ji, Xiao-duo, Jacobson, Kenneth A.

“…Acute stimulation of A3 adenosine receptors has been shown to intensify damage in an in vivo model of global cerebral ischemia and to induce cell death in cell…”
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Chronic NMDA receptor stimulation : therapeutic implications of its effect on adenosine A1 receptors by VON LUBITZ, D. K. J. E, KIM, J, BEENHAKKER, M, CARTER, M. F, LIN, R. C.-S, MESHULAM, Y, DALY, J. W, SHI, D, ZHOU, L.-M, JACOBSON, K. A

“…It is known that stimulation of adenosine A1 receptors has a modulatory effect on the excitability of postsynaptic NMDA receptors. Conversely, acute…”
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Effects of N6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice by Von Lubitz, D K, Paul, I A, Carter, M, Jacobson, K A

“…The effect of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) and antagonist 8-cyclopentyl-1,3-dipropylxanthine (CPX) on N-methyl-D-aspartate…”
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MK-801 is neuroprotective but does not improve survival in severe forebrain ischemia by Von Lubitz, D K, McKenzie, R J, Lin, R C, Devlin, T M, Skolnick, P

“…The effects of MK-801 on postischemic recovery, survival and neuronal preservation in the cortex, hippocampus and striatum were studied in Mongolian gerbils…”
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Neuroprotective activity of dimer of 16,16'-dimethyl-15-dehydroprostaglandin B1 (di-Calciphor) in cerebral ischemia by Lin, R C, Matesic, D F, McKenzie, R J, Devlin, T M, von Lubitz, D K

“…Post-ischemic treatment of di-Calciphor (16,16'-dimethyl-15- dehydroprostaglandin B1) significantly improves animal survival and prevents ischemia-induced…”
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