Search Results - "VON HIPPEL, P. H"

An Integrated Model of the Transcription Complex in Elongation, Termination, and Editing by von Hippel, Peter H.

“…Recent findings now allow the development of an integrated model of the thermodynamic, kinetic, and structural properties of the transcription complex in the…”
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Facilitated Target Location in Biological Systems by von Hippel, P H, Berg, O G

“…In 1970 Riggs et al. (1) reported that Escherichia coli lac repressor binding to λ DNA in vitro seemed to find its target (operator) site on the DNA at a rate…”
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A Physical Model for the Translocation and Helicase Activities of Escherichia coli Transcription Termination Protein Rho by Geiselmann, Johannes, Wang, Yan, Seifried, Steven E., von Hippel, Peter H.

“…Transcription termination protein Rho of Escherichia coli interacts with newly synthesized RNA chains and brings about their release from elongation complexes…”
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On the Specificity of DNA--Protein Interactions by Von Hippel, Peter H., Berg, Otto G.

“…In this paper we summarize the various factors that must be considered in establishing the operational specificity of the binding of a protein regulator of…”
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Transcription Termination at Intrinsic Terminators: The Role of the RNA Hairpin by Wilson, Kevin S., von Hippel, Peter H.

“…Intrinsic termination of transcription in Escherichia coli involves the formation of an RNA hairpin in the nascent RNA. This hairpin plays a central role in…”
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Structural and enzymatic studies of the T4 DNA replication system. I. Physical characterization of the polymerase accessory protein complex by JARVIS, T. C, PAUL, L. S, VON HIPPEL, P. H

“…In this study, we have investigated the structural and physical properties of the bacteriophage T4 DNA polymerase accessory proteins. We find that T4 gene 44…”
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Processive proofreading is intrinsic to T4 DNA polymerase by REDDY, M. K, WEITZEL, S. E, VON HIPPEL, P. H

“…DNA replication occurs in vivo with very high processivity, meaning that the replication complex assembles at the origin(s) of replication and then performs…”
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Molecular Mechanisms of the Functional Coupling of the Helicase (gp41) and Polymerase (gp43) of Bacteriophage T4 within the DNA Replication Fork by Delagoutte, Emmanuelle, von Hippel, Peter H

“…Processive strand-displacement DNA synthesis with the T4 replication system requires functional “coupling” between the DNA polymerase (gp43) and the helicase…”
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Transcript Elongation and Termination are Competitive Kinetic Processes by von Hippel, Peter H., Yager, Thomas D.

“…In this paper, we develop a kinetic approach to predict the efficiency of termination at intrinsic (factor independent) terminators of Escherichia coli and…”
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Protein-Nucleic Acid Interactions in Transcription: A Molecular Analysis by von Hippel, Peter H, Bear, David G, Morgan, William D, McSwiggen, James A

“…The authors review what is currently known about the transcription process, focusing on the sequence of events in which RNA polymerase is involved as it moves…”
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Assembly of a Functional Replication Complex without ATP Hydrolysis: A Direct Interaction of Bacteriophage T4 gp45 with T4 DNA Polymerase by Reddy, Michael K., Weitzel, Stephen E., von Hippel, Peter H.

“…The seven-protein bacteriophage T4 DNA replication complex can be manipulated in vitro to study mechanistic aspects of the elongation phase of DNA replication…”
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Escherichia coli transcription termination factor rho. II. Binding of oligonucleotide cofactors by YAN WANG, VON HIPPEL, P. H

“…The relative binding affinities for rho of the oligonucleotide rho ATPase cofactors studied in the accompanying paper (Wang, Y., and von Hippel, P. H. (1993)…”
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Structural and enzymatic studies of the T4 DNA replication system. II. ATPase properties of the polymerase accessory protein complex by JARVIS, T. C, PAUL, L. S, HOCKENSMITH, J. W, VON HIPPEL, P. H

“…In this paper we report a detailed enzymatic characterization of the interaction of the polymerase accessory protein complex of the T4 DNA replication system…”
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Multiple RNA Polymerase Conformations and GreA: Control of the Fidelity of Transcription by Erie, Dorothy A., Hajiseyedjavadi, Omid, Young, Mark C., von Hippel, Peter H.

“…Pre-steady state kinetics of misincorporation were used to investigate the addition of single nucleotides to nascent RNA by Escherichia coli RNA polymerase…”
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Escherichia coli transcription termination factor rho. I. ATPase activation by oligonucleotide cofactors by YAN WANG, VON HIPPEL, P. H

“…Rho protein is required to bring about RNA release from Escherichia coli transcription complexes paused at specific (rho-dependent) termination sites. Rho…”
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Betaine can eliminate the base pair composition dependence of DNA melting by Rees, William A, Yager, Thomas D, Korte, John, Von Hippel, Peter H

“…We show that the amino acid analogue betaine shares with small tetraalkylammonium ions [Melchior, W. B., Jr., & von Hippel, P. H. (1973) Proc. Natl. Acad. Sci…”
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Stimulation of the processivity of the DNA polymerase of bacteriophage T4 by the polymerase accessory proteins. The role of ATP hydrolysis by JARVIS, T. C, NEWPORT, J. W, VON HIPPEL, P. H

“…In this paper we examine the role of the DNA polymerase accessory proteins in modulating the processivity of DNA synthesis by the bacteriophage T4-coded five…”
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Laser cross-linking of nucleic acids to proteins. Methodology and first applications to the phage T4 DNA replication system by Hockensmith, J W, Kubasek, W L, Vorachek, W R, von Hippel, P H

“…Single-pulse (approximately 8 ns) ultraviolet laser excitation of protein-nucleic acid complexes can result in efficient and rapid covalent cross-linking of…”
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ATPase Activity of Transcription-Termination Factor Rho: Functional Dimer Model by Seifried, Steven E., Easton, John B., Von Hippel, Peter H.

“…Transcription-termination factor rho of Escherichia coli functions as an RNA-dependent ATPase that causes transcript release at specific rho-dependent…”
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Laser cross-linking of proteins to nucleic acids. I. Examining physical parameters of protein-nucleic acid complexes by HOCKENSMITH, J. W, KUBASEK, W. L, VORACHEK, W. R, VON HIPPEL, P. H

“…Pulsed laser cross-linking results in efficient and rapid formation of covalent bonds between proteins and the nucleic acids to which they are bound, creating…”
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