Search Results - "VON GALL, CHARLOTTE"
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Analysis of Spatial and Temporal Distribution of Purinergic P2 Receptors in the Mouse Hippocampus
Published in International journal of molecular sciences (01-08-2021)“…ATP and other nucleotides are important glio-/neurotransmitters in the central nervous system. They bind to purinergic P2X and P2Y receptors that are…”
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The Role of Purinergic Receptors in the Circadian System
Published in International journal of molecular sciences (12-05-2020)“…The circadian system is an internal time-keeping system that synchronizes the behavior and physiology of an organism to the 24 h solar day. The master…”
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The Effects of Light and the Circadian System on Rhythmic Brain Function
Published in International journal of molecular sciences (03-03-2022)“…Life on earth has evolved under the influence of regularly recurring changes in the environment, such as the 24 h light/dark cycle. Consequently, organisms…”
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The Role of the Melatoninergic System in Circadian and Seasonal Rhythms-Insights From Different Mouse Strains
Published in Frontiers in physiology (12-04-2022)“…The melatoninergic system comprises the neurohormone melatonin and its molecular targets. The major source of melatonin is the pineal organ where melatonin is…”
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From in vitro to ex vivo: subcellular localization and uptake of graphene quantum dots into solid tumors
Published in Nanotechnology (27-09-2019)“…Among various nanoparticles tested for pharmacological applications over the recent years, graphene quantum dots (GQDs) seem to be promising candidates for the…”
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Sleep Duration on Workdays Is Correlated with Subjective Workload and Subjective Impact of High Workload on Sleep in Young Healthy Adults
Published in Brain sciences (18-05-2023)“…Psychosocial stress is widespread worldwide and particularly affects young adults. There is a close and bidirectional relationship between sleep quality and…”
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Adult Neurogenesis under Control of the Circadian System
Published in Cells (Basel, Switzerland) (22-02-2022)“…The mammalian circadian system is a hierarchically organized system, which controls a 24-h periodicity in a wide variety of body and brain functions and…”
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Bmal1‐deficiency affects glial synaptic coverage of the hippocampal mossy fiber synapse and the actin cytoskeleton in astrocytes
Published in Glia (01-05-2020)“…Bmal1 is an essential component of the molecular clockwork, which drives circadian rhythms in cell function. In Bmal1‐deficient (Bmal1−/−) mice,…”
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Time‐dependent changes in proliferation, DNA damage and clock gene expression in hepatocellular carcinoma and healthy liver of a transgenic mouse model
Published in International journal of cancer (01-01-2021)“…Hepatocellular carcinoma (HCC) is highly resistant to anticancer therapy and novel therapeutic strategies are needed. Chronotherapy may become a promising…”
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Chronotype-Dependent Sleep Loss Is Associated with a Lower Amplitude in Circadian Rhythm and a Higher Fragmentation of REM Sleep in Young Healthy Adults
Published in Brain sciences (01-10-2023)“…In modern society, the time and duration of sleep on workdays are primarily determined by external factors, e.g., the alarm clock. This can lead to a…”
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Acute Circadian Disruption Due to Constant Light Promotes Caspase 1 Activation in the Mouse Hippocampus
Published in Cells (Basel, Switzerland) (01-07-2023)“…In mammals, the circadian system controls various physiological processes to maintain metabolism, behavior, and immune function during a daily 24 h cycle…”
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Sex-Dependent Effects of Bmal1-Deficiency on Mouse Cerebral Cortex Infarction in Response to Photothrombotic Stroke
Published in International journal of molecular sciences (11-10-2018)“…Stroke is a leading cause of disability and death worldwide. There is increasing evidence that occurrence of ischemic stroke is affected by circadian system…”
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Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis
Published in Brain (London, England : 1878) (01-04-2020)“…Chronic disability in multiple sclerosis is linked to neuroaxonal degeneration. 4-aminopyridine (4-AP) is used and licensed as a symptomatic treatment to…”
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Does a Red House Affect Rhythms in Mice with a Corrupted Circadian System?
Published in International journal of molecular sciences (25-02-2021)“…The circadian rhythms of body functions in mammals are controlled by the circadian system. The suprachiasmatic nucleus (SCN) in the hypothalamus orchestrates…”
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Deficiency of the clock gene Bmal1 affects neural progenitor cell migration
Published in Brain Structure and Function (01-01-2019)“…We demonstrate the impact of a disrupted molecular clock in Bmal1-deficient (Bmal1 −/− ) mice on migration of neural progenitor cells (NPCs). Proliferation of…”
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Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis
Published in Journal of neuroinflammation (04-11-2019)“…Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and…”
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Connexin30 and Connexin43 show a time-of-day dependent expression in the mouse suprachiasmatic nucleus and modulate rhythmic locomotor activity in the context of chronodisruption
Published in Cell communication and signaling (11-06-2019)“…The astroglial connexins Cx30 and Cx43 contribute to many important CNS functions including cognitive behaviour, motoric capacity and regulation of the…”
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The endogenous melatonin (MT) signal facilitates reentrainment of the circadian system to light-induced phase advances by acting upon MT2 receptors
Published in Chronobiology international (01-05-2012)“…The indolamine melatonin is an important rhythmic endocrine signal in the circadian system. Exogenous melatonin can entrain circadian rhythms in physiology and…”
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Impaired Photic Entrainment of Spontaneous Locomotor Activity in Mice Overexpressing Human Mutant α-Synuclein
Published in International journal of molecular sciences (03-06-2018)“…Parkinson's disease (PD) is characterized by distinct motor and non-motor symptoms. Sleep disorders are the most frequent and challenging non-motor symptoms in…”
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Impact of Targeted Deletion of the Circadian Clock Gene Bmal1 in Excitatory Forebrain Neurons on Adult Neurogenesis and Olfactory Function
Published in International journal of molecular sciences (19-02-2020)“…The circadian system is an endogenous timekeeping system that synchronizes physiology and behavior with the 24 h solar day. Mice with total deletion of the…”
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