Search Results - "VOLZ, Astrid"

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  1. 1

    Impact of endogenous esterase activity on in vitro p-glycoprotein profiling of dabigatran etexilate in Caco-2 monolayers by Ishiguro, Naoki, Kishimoto, Wataru, Volz, Astrid, Ludwig-Schwellinger, Eva, Ebner, Thomas, Schaefer, Olaf

    Published in Drug metabolism and disposition (01-02-2014)
    “…Dabigatran etexilate, a double prodrug of dabigatran, is a reversible, competitive, direct thrombin inhibitor that has been approved for use in many countries…”
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    Journal Article
  2. 2

    Compound profiling for ABCC2 (MRP2) using a fluorescent microplate assay system by Förster, Frank, Volz, Astrid, Fricker, Gert

    “…Purpose: To establish a fluorescent dye (Glutathione methylfluorescein, GSMF) based assay to rapidly screen compounds for drug efflux interactions with the…”
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    Journal Article
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    Altered drug disposition of the platelet activating factor antagonist apafant in mdr1a knockout mice by Leusch, Andreas, Volz, Astrid, Müller, Gabriele, Wagner, Andrea, Sauer, Achim, Greischel, Andreas, Roth, Willy

    “…The aim of the present study was to determine a potential impact of P-glycoprotein (P-gp) on the tissue distribution and disposition of apafant (WEB 2086, CAS…”
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    Journal Article
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    Longevity of adult ventricular rat heart muscle cells in serum-free primary culture by Volz, A, Piper, H M, Siegmund, B, Schwartz, P

    “…The study had two aims: first, to improve the longevity of isolated adult cardiomyocytes in serum-free culture, and, second, to investigate whether…”
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    Journal Article