Search Results - "VITO, G."
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C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation
Published in The EMBO journal (04-01-2022)“…Intronic GGGGCC (G4C2) hexanucleotide repeat expansion within the human C9orf72 gene represents the most common cause of familial forms of amyotrophic lateral…”
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2
RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?
Published in Journal of extracellular vesicles (01-12-2020)“…Extracellular vesicles (EVs) are heterogeneous membranous particles released from the cells through different biogenetic and secretory mechanisms. We now…”
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3
A novel high throughput biochemical assay to evaluate the HuR protein-RNA complex formation
Published in PloS one (12-08-2013)“…The RNA binding protein HuR/ELAVL1 binds to AU-rich elements (AREs) promoting the stabilization and translation of a number of mRNAs into the cytoplasm,…”
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4
EGCG Disrupts the LIN28B/Let-7 Interaction and Reduces Neuroblastoma Aggressiveness
Published in International journal of molecular sciences (01-05-2024)“…Neuroblastoma (NB) is the most commonly diagnosed extracranial solid tumor in children, accounting for 15% of all childhood cancer deaths. Although the 5-year…”
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5
High rate of subclinical chikungunya virus infection and association of neutralizing antibody with protection in a prospective cohort in the Philippines
Published in PLoS neglected tropical diseases (01-05-2015)“…Chikungunya virus (CHIKV) is a globally re-emerging arbovirus for which previous studies have indicated the majority of infections result in symptomatic…”
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6
Enzymatically active apurinic/apyrimidinic endodeoxyribonuclease 1 is released by mammalian cells through exosomes
Published in The Journal of biological chemistry (01-01-2021)“…The apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1), the main AP-endonuclease of the DNA base excision repair pathway, is a key molecule of interest to…”
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Interfering with HuR–RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors
Published in Journal of medicinal chemistry (22-02-2018)“…The human antigen R (HuR) is an RNA-binding protein known to modulate the expression of target mRNA coding for proteins involved in inflammation,…”
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Zebrafish Melanoma-Derived Interstitial EVs Are Carriers of ncRNAs That Induce Inflammation
Published in International journal of molecular sciences (14-05-2022)“…Extracellular vesicles (EVs) are membranous particles released by all cell types. Their role as functional carrier of bioactive molecules is boosted by cells…”
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Epidemiology of dengue disease in the Philippines (2000-2011): a systematic literature review
Published in PLoS neglected tropical diseases (01-11-2014)“…This literature analysis describes the available dengue epidemiology data in the Philippines between 2000 and 2011. Of 253 relevant data sources identified,…”
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10
Laser-written vapor cells for chip-scale atomic sensing and spectroscopy
Published in Optics express (18-07-2022)“…We report the fabrication of alkali-metal vapor cells using femtosecond laser machining. This laser-written vapor-cell (LWVC) technology allows…”
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Zika virus infection, Philippines, 2012
Published in Emerging infectious diseases (01-04-2015)Get full text
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Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases
Published in Scientific reports (10-03-2016)“…Neurodegenerative diseases (NDs) are often associated with the presence of misfolded protein inclusions. The chaperone HSPB8 is upregulated in mice, the human…”
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Editorial: RNA recognition landscapes and anticancer drug targeting
Published in Frontiers in oncology (19-06-2023)Get full text
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14
Spectral Analysis of Electromagnetic Diffraction Phenomena in Angular Regions Filled by Arbitrary Linear Media
Published in Applied sciences (01-10-2024)“…A general theory for solving electromagnetic diffraction problems with impenetrable/penetrable wedges immersed in/made of an arbitrary linear (bianistropic)…”
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15
Association between seasonal flu vaccination and COVID-19 among healthcare workers
Published in Occupational medicine (Oxford) (30-12-2020)“…Abstract Background In next fall and winter, SARS-CoV-2 could circulate in parallel with seasonal influenza. The dual epidemics will result in considerable…”
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16
Network representations of angular regions for electromagnetic scattering
Published in PloS one (17-08-2017)“…Network modeling in electromagnetics is an effective technique in treating scattering problems by canonical and complex structures. Geometries constituted of…”
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Physiological profile comparison between high intensity functional training, endurance and power athletes
Published in European journal of applied physiology (01-02-2022)“…Introduction High intensity functional trainings (HIFT), a recent development of high intensity trainings, includes in the same training session components of…”
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Prediction of high incidence of dengue in the Philippines
Published in PLoS neglected tropical diseases (01-04-2014)“…Accurate prediction of dengue incidence levels weeks in advance of an outbreak may reduce the morbidity and mortality associated with this neglected disease…”
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Reconstruction of 60 Years of Chikungunya Epidemiology in the Philippines Demonstrates Episodic and Focal Transmission
Published in The Journal of infectious diseases (15-02-2016)“…Proper understanding of the long-term epidemiology of chikungunya has been hampered by poor surveillance. Outbreak years are unpredictable and cases often…”
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Epidemiology of Japanese encephalitis in the Philippines: a systematic review
Published in PLoS neglected tropical diseases (01-03-2015)“…Japanese encephalitis virus (JEV) is an important cause of encephalitis in most of Asia, with high case fatality rates and often significant neurologic…”
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