Search Results - "VITAL, Maria A. B. F"

Decrease in Adult Neurogenesis and Neuroinflammation Are Involved in Spatial Memory Impairment in the Streptozotocin-Induced Model of Sporadic Alzheimer’s Disease in Rats by Bassani, Taysa Bervian, Bonato, Jéssica M., Machado, Meira M. F., Cóppola-Segovia, Valentín, Moura, Eric L. R., Zanata, Silvio M., Oliveira, Rúbia M. M. W., Vital, Maria A. B. F.

“…Early impairments in cerebral glucose metabolism and insulin signaling pathways may participate in the pathogenesis of the sporadic form of Alzheimer’s disease…”
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Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine by Santiago, Ronise M., Barbieiro, Janaína, Lima, Marcelo M.S., Dombrowski, Patrícia A., Andreatini, Roberto, Vital, Maria A.B.F.

“…Depression is a frequently encountered non-motor feature of Parkinson's disease (PD) and it can have a significant impact on patient's quality of life…”
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Synthesis, Characterization, and Low-Toxicity Study of a Magnesium(II) Complex Containing an Isovanillate Group by Marchi, Rafael C, Silva, Eldevan S, Santos, Josenilton J, Guiloski, Izonete C, de Jesus, Hugo Cesar R, de Aguiar, Inara, Kock, Flavio V. C, Venâncio, Tiago, da Silva, Maria Fátima G. F, Fernandes, João Batista, Vital, Maria A. B. F, Souza, Leonardo Castro, Silva de Assis, Helena C, Skibsted, Leif H, Carlos, Rose M

“…The beneficial effect of polyphenols and magnesium­(II) against oxidative stress motivated our research group to explore the antioxidant activity of phenMgIso,…”
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Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine by BARBIERO, Janaína K, SANTIAGO, Ronise M, PERSIKE, Daniele Suzete, DA SILVA FERNANDES, Maria José, TONIN, Fernanda S, DA CUNHA, Claudio, BOSCHEN, Suelen Lucio, LIMA, Marcelo M. S, VITAL, Maria A. B. F

“…A large body of evidence suggests that peroxisome proliferator-activated receptor (PPAR) agonists may improve some of the pathological features of Parkinson's…”
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Induction of depressive-like behavior by intranigral 6-OHDA is directly correlated with deficits in striatal dopamine and hippocampal serotonin by Santiago, Ronise M., Barbiero, Janaína, Gradowski, Raisa W., Bochen, Suelen, Lima, Marcelo M.S., Da Cunha, Cláudio, Andreatini, Roberto, Vital, Maria A.B.F.

“…•The intranigral infusion of 6-OHDA was able to promote a depressive-like behavior.•6-OHDA-lesioned rats exhibited a reduction in the levels of hippocampal…”
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PPAR-α agonist fenofibrate protects against the damaging effects of MPTP in a rat model of Parkinson's disease by Barbiero, Janaína K., Santiago, Ronise, Tonin, Fernanda S., Boschen, Suelen, da Silva, Luísa Mota, de Paula Werner, Maria Fernanda, da Cunha, Claudio, Lima, Marcelo M.S., Vital, Maria A.B.F.

“…Parkinson's disease (PD) is a chronic neurodegenerative disorder characterized by progressive loss of dopaminergic neurons in the substantia nigra pars…”
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Neuroprotective and antidepressant-like effects of melatonin in a rotenone-induced Parkinson’s disease model in rats by Bassani, Taysa B, Gradowski, Raisa W, Zaminelli, Tiago, Barbiero, Janaína K, Santiago, Ronise M, Boschen, Suelen L, da Cunha, Claudio, Lima, Marcelo M.S, Andreatini, Roberto, Vital, Maria A.B.F

“…Abstract Parkinson׳s disease (PD) is a neurodegenerative disorder characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars…”
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Ineffectiveness of saxagliptin as a neuroprotective drug in 6‐OHDA‐lesioned rats by Turnes, Joelle de Melo, Bassani, Taysa Bervian, Souza, Leonardo C., Vital, Maria A. B. F.

“…Objectives To determine whether the drug saxagliptin, a dipeptidyl peptidase‐4 (DPP‐4) inhibitor which is utilized for the treatment of Diabetes Mellitus, has…”
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The roles of the nucleus accumbens core, dorsomedial striatum, and dorsolateral striatum in learning: Performance and extinction of Pavlovian fear-conditioned responses and instrumental avoidance responses by Wendler, Etieli, Gaspar, Jessica C.C., Ferreira, Tatiana L., Barbiero, Janaína K., Andreatini, Roberto, Vital, Maria A.B.F., Blaha, Charles D., Winn, Philip, Da Cunha, Claudio

“…•Lesions of the NAc-co impair learning of the Pavlovian component of CARs.•Lesions of the NAc-co, DLS, and DMS impair learning of the instrumental…”
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Putative role of monoamines in the antidepressant-like mechanism induced by striatal MT2 blockade by Noseda, Ana Carolina D., Rodrigues, Lais S., Targa, Adriano D.S., Aurich, Mariana F., Vital, Maria A.B.F., Da Cunha, Cláudio, Lima, Marcelo M.S.

“…•Antidepressant effects triggered by MT2 blockade in the striatum.•Association of striatal MT2 blockade and REMSD generates decreases 5-HT.•4-P-PDOT increased…”
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Antidepressant-like effect of celecoxib piroxicam in rat models of depression by Santiago, Ronise M., Barbiero, Janaína, Martynhak, Bruno J., Boschen, Suelen L., da Silva, Luisa M., Werner, Maria F. P., Da Cunha, Claudio, Andreatini, Roberto, Lima, Marcelo M. S., Vital, Maria A. B. F.

“…Beyond the current hypothesis of depression, several new biological substrates have been proposed for this disorder. The present study investigated whether the…”
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The role of the substantia nigra pars compacta in regulating sleep patterns in rats by Lima, Marcelo M S, Andersen, Monica L, Reksidler, Angela B, Vital, Maria A B F, Tufik, Sergio

“…As of late, dopaminergic neurotransmission has been recognized to be involved in the generation of sleep disturbances. Increasing evidence shows that sleep…”
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Acute but not chronic administration of pioglitazone promoted behavioral and neurochemical protective effects in the MPTP model of Parkinson's disease by Barbiero, Janaína K., Santiago, Ronise M., Lima, Marcelo M.S., Ariza, Deborah, Morais, Lívia H., Andreatini, Roberto, Vital, Maria A.B.F.

“…▶ Beneficial effects of pioglitazone treatment on motor and neurochemical parameters. ▶ Pioglitazone was effective in reversing DA depletion at a dose of 30…”
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The COX-2 inhibitor parecoxib produces neuroprotective effects in MPTP-lesioned rats by Reksidler, Angela B., Lima, Marcelo M.S., Zanata, Sílvio M., Machado, Hidevaldo B., da Cunha, Cláudio, Andreatini, Roberto, Tufik, Sergio, Vital, Maria A.B.F.

“…The present study investigated the effects of the selective cyclooxygenase-2 (COX-2) inhibitor parecoxib (Bextra™) in the prevention of motor and cognitive…”
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Paradoxical sleep deprivation modulates tyrosine hydroxylase expression in the nigrostriatal pathway and attenuates motor deficits induced by dopaminergic depletion by Lima, Marcelo M S, Andersen, Monica L, Reksidler, Angela B, Ferraz, Anete C, Vital, Maria A B F, Tufik, Sergio

“…The nigrostriatal pathway is very likely involved in sleep regulation, considering the occurrence and high prevalence of sleep-related disorders in patients…”
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Intranigral LPS Administration Produces Dopamine, Glutathione but not Behavioral Impairment in Comparison to MPTP and 6-OHDA Neurotoxin Models of Parkinson’s Disease by Ariza, Deborah, Lima, Marcelo M. S., Moreira, Camila G., Dombrowski, Patrícia A., Avila, Thiago V., Allemand, Alexandra, B Mendes, Daniel A. G., Cunha, Claudio Da, Vital, Maria A. B. F.

“…The current investigation compared intranigral lipopolysaccharide (LPS), 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 6-hydroxydopamine (6-OHDA)…”
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Effects of curcumin on short-term spatial and recognition memory, adult neurogenesis and neuroinflammation in a streptozotocin-induced rat model of dementia of Alzheimer’s type by Bassani, Taysa B., Turnes, Joelle M., Moura, Eric L.R., Bonato, Jéssica M., Cóppola-Segovia, Valentín, Zanata, Silvio M., Oliveira, Rúbia M.M.W., Vital, Maria A.B.F.

“…•Streptozotocin caused deficits in short-term spatial and recognition memory.•Streptozotocin decreased adult neurogenesis and increased…”
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Anxiety-like behavior induced by 6-OHDA animal model of Parkinson’s disease may be related to a dysregulation of neurotransmitter systems in brain areas related to anxiety by Vieira, Jeane Cristina F., Bassani, Taysa B., Santiago, Ronise M., de O. Guaita, Gisele, Zanoveli, Janaína M., da Cunha, Claudio, Vital, Maria A.B.F.

“…•The model of 6-OHDA-induced parkinsonism in rats results in anxiety-like behaviour.•In contrast with dopamine and norepinephrine, serotonin significantly…”
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Fenofibrate promotes neuroprotection in a model of rotenone-induced Parkinson’s disease by Barbiero, Janaína K., Ramos, Daniele C., Boschen, Suelen, Bassani, Taysa, Da Cunha, Cláudio, Vital, Maria A. B. F.

“…Parkinson’s disease is a neurodegenerative disease, the etiology of which remains unknown, but some likely causes include oxidative stress, mitochondrial…”
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Andrographolide Attenuates Short-Term Spatial and Recognition Memory Impairment and Neuroinflammation Induced by a Streptozotocin Rat Model of Alzheimer’s Disease by Souza, Leonardo C., Andrade, Marcos K., Azevedo, Evellyn M., Ramos, Daniele C., Bail, Ellen L., Vital, Maria A. B. F.

“…Alzheimer’s disease (AD) is a neurodegenerative disorder clinically manifested by a gradual cognitive decline. Intracerebroventricular injection (ICV) of…”
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