Search Results - "VISO, Alma"

From Allylic Sulfoxides to Allylic Sulfenates: Fifty Years of a Never-Ending [2,3]-Sigmatropic Rearrangement by Colomer, Ignacio, Velado, Marina, Fernández de la Pradilla, Roberto, Viso, Alma

“…The [2,3]-sigmatropic rearrangement of allylic sulfoxides to allylic sulfenates is a reversible process, generally shifted toward the sulfoxide. In the…”
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Sulfoxide-Directed Enantioselective Synthesis of Functionalized Tetrahydropyridines by Fernández de la Pradilla, Roberto, Simal, Carmen, Bates, Robert H, Viso, Alma, Infantes, Lourdes

“…The highly selective base-promoted cyclization of enantiopure sulfinyl dienamines provides stereodefined sulfinyl 1,2,3,6-tetrahydropyridines (dr up to 99:1)…”
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Remote Stereocontrol in the Synthesis of Acyclic 1,4-Diols and 1,4‑Aminoalcohols from 2‑Sulfinyl Dienes by Fernández de la Pradilla, Roberto, Velado, Marina, Colomer, Ignacio, Simal, Carmen, Viso, Alma, Gornitzka, Heinz, Hemmert, Catherine

“…The highly diastereoselective conjugate addition of alcohols and amines (RXH) to enantiopure 2-sulfinyl dienes renders transient allylic sulfoxides which…”
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An Approach to the Stereoselective Synthesis of Enantiopure Dihydropyrroles and Aziridines from a Common Sulfinyl-Sulfinamide Intermediate by Viso, Alma, Fernández de la Pradilla, Roberto, Ureña, Mercedes, Bates, Robert H, del Águila, Miguel A, Colomer, Ignacio

“…The diastereoselective addition of lithiated vinyl sulfoxides to enantiopure sulfinimines provides direct access to a wide assortment of allylic sulfinamides…”
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Enantiopure 1,4-Diols and 1,4-Aminoalcohols via Stereoselective Acyclic Sulfoxide−Sulfenate Rearrangement by Fernández de la Pradilla, Roberto, Colomer, Ignacio, Ureña, Mercedes, Viso, Alma

“…Treatment of acyclic α-hydroxy and α-tosylamino sulfinyl dienes with amines affords enantiopure 1,4-diol or 1,4-hydroxysulfonamide derivatives in good yields…”
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The medicinal chemistry of agents targeting monoacylglycerol lipase by Viso, Alma, Cisneros, José A, Ortega-Gutiérrez, Silvia

“…Monoacylglycerol lipase (MAGL) has been recently proposed as the main enzymatic activity responsible for the in vivo hydrolysis of the most abundant…”
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Formal synthesis of ent-dysiherbaine from sulfinyl dihydropyrans by sigmatropic rearrangement and tethered aminohydroxylation by Fernández de la Pradilla, Roberto, Lwoff, Nadia, Viso, Alma

“…A stereospecific [2,3]-sigmatropic rearrangement of a sulfinyl dihydropyran, followed by a tethered aminohydroxylation reaction, are the key steps of a formal…”
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Highly Diastereoselective [3+2] Cycloadditions between Nonracemic p-Tolylsulfinimines and Iminoesters: An Efficient Entry to Enantiopure Imidazolidines and Vicinal Diaminoalcohols by Viso, Alma, Fernández de la Pradilla, Roberto, García, Ana, Guerrero-Strachan, Carlos, Alonso, Marta, Tortosa, Mariola, Flores, Aida, Martínez-Ripoll, Martín, Fonseca, Isabel, André, Isabelle, Rodríguez, Ana

“…A new procedure for the asymmetric synthesis of imidazolidines and vicinal diamines is reported. The 1,3‐dipolar cycloaddition between nonracemic…”
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Sulfur-Mediated Synthesis of Substituted Tetrahydrofurans: Application to the Synthesis of Goniofufurone by Fernández de la Pradilla, Roberto, Viso, Alma, Fernández, Jorge, Gómez, Antonio

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Site-Selective Functionalization of C(sp3) Vicinal Boronic Esters by Viso, Alma, Fernández de la Pradilla, Roberto, Tortosa, Mariola

“…Selective functionalization of the C–B bond in 1,2-bis­(boronate) esters has emerged as a powerful tool to prepare 1,2-difunctionalized compounds with…”
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Involvement of cannabinoids in cellular proliferation by López-Rodríguez, María L, Viso, Alma, Ortega-Gutiérrez, Silvia, Díaz-Laviada, Inés

“…The endogenous canabinoid system (ECS) is involved in the regulation of an important number of central and peripheral physiological effects. Among all these…”
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Synthesis of Tetrahydrofurfurylamines Related to Muscarine by Fernández de la Pradilla, Roberto, Manzano, Pilar, Viso, Alma, Fernández, Javier, Gómez, Antonio

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VR1 receptor modulators as potential drugs for neuropathic pain by López-Rodríguez, María L, Viso, Alma, Ortega-Gutiérrez, Silvia

“…The involvement of VR(1) in the endogenous pain signalling has converted this receptor into a promising therapeutic target for the development of a new family…”
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Enantioselective Suzuki cross-coupling of 1,2-diboryl cyclopropanes by Teresa, Javier, Velado, Marina, Fernández de la Pradilla, Roberto, Viso, Alma, Lozano, Blanca, Tortosa, Mariola

“…Herein, we describe the catalytic enantioselective cross-coupling of 1,2-bisboronic esters. Prior work on group specific cross coupling is limited to the use…”
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Diastereodivergent Synthesis of 2‑Ene-1,4-hydroxy Sulfides from 2‑Sulfinyl Dienes via Tandem Sulfa-Michael/Sulfoxide-Sulfenate Rearrangement by Velado, Marina, Fernández de la Pradilla, Roberto, Viso, Alma

“…The highly diastereoselective sulfa-Michael addition of thiolates to enantiopure 2-sulfinyl dienes leads to anti or syn 2-ene-1,4-hydroxy sulfides in good…”
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Base-Induced Sulfoxide-Sulfenate Rearrangement of 2‑Sulfinyl Dienes for the Regio- and Stereoselective Synthesis of Enantioenriched Dienyl Diols by Velado, Marina, Martinović, Manuel, Alonso, Inés, Tortosa, Mariola, Fernández de la Pradilla, Roberto, Viso, Alma

“…The base-induced [2,3]-sigmatropic rearrangement of a series of enantiopure 2-sulfinyl dienes has been examined and optimized using a combination of NaH and i…”
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Sulfinyl‐Mediated Stereoselective Functionalization of Acyclic Conjugated Dienes by Colomer, Ignacio, Ureña, Mercedes, Viso, Alma, Fernández de la Pradilla, Roberto

“…The chemo‐ and stereocontrolled functionalization of conjugated sulfinyl dienes in a cascade process that involves a conjugate addition, diastereoselective…”
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Enantiospecific Synthesis of 1,3‐Disubstituted Allenes from Propargylic Carbonates through a Borylation‐1,2‐Elimination Process by Jarava‐Barrera, Carlos, Parra, Alejandro, Quesada, Sergio, Orgaz‐Gordillo, Sergio, Fernández de la Pradilla, Roberto, Viso, Alma, Teresa, Javier, Alonso, Inés, Tortosa, Mariola

“…An array of enantioenriched vinyl boronates bearing an allylic carbonate moiety have been prepared through selective hydroboration of propargyl carbonates…”
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Update 1 of: α,β-Diamino Acids: Biological Significance and Synthetic Approaches by Viso, Alma, Fernández de la Pradilla, Roberto, Tortosa, Mariola, García, Ana, Flores, Aida

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Diastereodivergent Synthesis of 2-Ene-1,4-hydroxy Sulfides from 2-Sulfinyl Dienes via Tandem Sulfa-Michael/Sulfoxide-Sulfenate Rearrangement by Velado, Marina, Fernández de la Pradilla, Roberto, Viso, Alma

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