Search Results - "VISCONTE, Valeria"

Using machine learning to unravel the intricacy of acute myeloid leukemia by Guarnera, Luca, Visconte, Valeria

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Capturing the unpredictability of stem cells by Durmaz, Arda, Visconte, Valeria

“…A new mathematical model that can be applied to both single-cell and bulk DNA sequencing data sheds light on the processes governing population dynamics in…”
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Deciphering the Therapeutic Resistance in Acute Myeloid Leukemia by Gurnari, Carmelo, Pagliuca, Simona, Visconte, Valeria

“…Acute myeloid leukemia (AML) is a clonal hematopoietic disorder characterized by abnormal proliferation, lack of cellular differentiation, and infiltration of…”
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KMT2A Rearrangements in Leukemias: Molecular Aspects and Therapeutic Perspectives by Guarnera, Luca, D'Addona, Matteo, Bravo-Perez, Carlos, Visconte, Valeria

“…(alias: mixed-lineage leukemia [ ]) gene mapping on chromosome 11q23 encodes the lysine-specific histone N-methyltransferase 2A and promotes transcription by…”
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The Interactome between Metabolism and Gene Mutations in Myeloid Malignancies by Gurnari, Carmelo, Pagliuca, Simona, Visconte, Valeria

“…The study of metabolic deregulation in myeloid malignancies has led to the investigation of metabolic-targeted therapies considering that cells undergoing…”
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Disruption of Autophagic Degradation with ROC-325 Antagonizes Renal Cell Carcinoma Pathogenesis by Carew, Jennifer S, Espitia, Claudia M, Zhao, William, Han, Yingchun, Visconte, Valeria, Phillips, James, Nawrocki, Steffan T

“…Although autophagy plays important roles in malignant pathogenesis and drug resistance, there are few clinical agents that disrupt this pathway, and the…”
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Personalized Risk Schemes and Machine Learning to Empower Genomic Prognostication Models in Myelodysplastic Syndromes by Awada, Hussein, Gurnari, Carmelo, Durmaz, Arda, Awada, Hassan, Pagliuca, Simona, Visconte, Valeria

“…Myelodysplastic syndromes (MDS) are characterized by variable clinical manifestations and outcomes. Several prognostic systems relying on clinical factors and…”
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Individual HLA heterogeneity and its implications for cellular immune evasion in cancer and beyond by Pagliuca, Simona, Gurnari, Carmelo, Rubio, Marie Thérèse, Visconte, Valeria, Lenz, Tobias L.

“…Structural and functional variability of human leukocyte antigen (HLA) is the foundation for competent adaptive immune responses against pathogen and tumor…”
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Clinical and Molecular Determinants of Clonal Evolution in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria by Gurnari, Carmelo, Pagliuca, Simona, Prata, Pedro Henrique, Galimard, Jacques-Emmanuel, Catto, Luiz Fernando B, Larcher, Lise, Sebert, Marie, Allain, Vincent, Patel, Bhumika J, Durmaz, Arda, Pinto, Andre L, Inacio, Mariana C B, Hernandez, Lucie, Dhedin, Nathalie, Caillat-Zucman, Sophie, Clappier, Emmanuelle, Sicre de Fontbrune, Flore, Voso, Maria Teresa, Visconte, Valeria, Peffault de Latour, Régis, Soulier, Jean, Calado, Rodrigo T, Socié, Gérard, Maciejewski, Jaroslaw P

“…Secondary myeloid neoplasms (sMNs) remain the most serious long-term complications in patients with aplastic anemia (AA) and paroxysmal nocturnal…”
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Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis by Makishima, Hideki, Visconte, Valeria, Sakaguchi, Hirotoshi, Jankowska, Anna M., Abu Kar, Sarah, Jerez, Andres, Przychodzen, Bartlomiej, Bupathi, Manoj, Guinta, Kathryn, Afable, Manuel G., Sekeres, Mikkael A., Padgett, Richard A., Tiu, Ramon V., Maciejewski, Jaroslaw P.

“…Myelodysplastic syndromes (MDSs) are chronic and often progressive myeloid neoplasms associated with remarkable heterogeneity in the histomorphology and…”
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Immunotherapy in Acute Myeloid Leukemia: A Literature Review of Emerging Strategies by Guarnera, Luca, Bravo-Perez, Carlos, Visconte, Valeria

“…In the last twenty years, we have witnessed a paradigm shift in the treatment and prognosis of acute myeloid leukemia (AML), thanks to the introduction of new…”
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Machine learning integrates genomic signatures for subclassification beyond primary and secondary acute myeloid leukemia by Awada, Hassan, Durmaz, Arda, Gurnari, Carmelo, Kishtagari, Ashwin, Meggendorfer, Manja, Kerr, Cassandra M., Kuzmanovic, Teodora, Durrani, Jibran, Shreve, Jacob, Nagata, Yasunobu, Radivoyevitch, Tomas, Advani, Anjali S., Ravandi, Farhad, Carraway, Hetty E., Nazha, Aziz, Haferlach, Claudia, Saunthararajah, Yogen, Scott, Jacob, Visconte, Valeria, Kantarjian, Hagop, Kadia, Tapan, Sekeres, Mikkael A., Haferlach, Torsten, Maciejewski, Jaroslaw P.

“…Although genomic alterations drive the pathogenesis of acute myeloid leukemia (AML), traditional classifications are largely based on morphology, and…”
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Large granular lymphocytic leukemia coexists with myeloid clones and myelodysplastic syndrome by Durrani, Jibran, Awada, Hassan, Kishtagari, Ashwin, Visconte, Valeria, Kerr, Cassandra, Adema, Vera, Nagata, Yasunobu, Kuzmanovic, Teodora, Hong, Sanghee, Patel, Bhumika, Nazha, Aziz, Lichtin, Alan, Mukherjee, Sudipto, Saunthararajah, Yogen, Carraway, Hetty, Sekeres, Mikkael, Maciejewski, Jaroslaw P.

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Rational management approach to pure red cell aplasia by Balasubramanian, Suresh Kumar, Sadaps, Meena, Thota, Swapna, Aly, Mai, Przychodzen, Bartlomiej P, Hirsch, Cassandra M, Visconte, Valeria, Radivoyevitch, Tomas, Maciejewski, Jaroslaw P

“…Pure red cell aplasia is an orphan disease, and as such lacks rationally established standard therapies. Most cases are idiopathic; a subset is…”
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Therapy-Related Myeloid Neoplasm: Biology and Mechanistic Aspects of Malignant Progression by Travaglini, Serena, Marinoni, Massimiliano, Visconte, Valeria, Guarnera, Luca

“…Therapy-related myeloid neoplasms (t-MN) arise after a documented history of chemo/radiotherapy as treatment for an unrelated condition and account for 10-20%…”
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The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders by Pagliuca, Simona, Gurnari, Carmelo, Awada, Hassan, Kishtagari, Ashwin, Kongkiatkamon, Sunisa, Terkawi, Laila, Zawit, Misam, Guan, Yihong, LaFramboise, Thomas, Jha, Babal K., Patel, Bhumika J., Hamilton, Betty K., Majhail, Navneet S., Lundgren, Sofie, Mustjoki, Satu, Saunthararajah, Yogen, Visconte, Valeria, Chan, Timothy A., Yang, Chao-Yie, Lenz, Tobias L., Maciejewski, Jaroslaw P.

“…Idiopathic aplastic anemia (IAA) is a rare autoimmune bone marrow failure (BMF) disorder initiated by a human leukocyte antigen (HLA)-restricted T-cell…”
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Is nature truly healing itself? Spontaneous remissions in Paroxysmal Nocturnal Hemoglobinuria by Gurnari, Carmelo, Pagliuca, Simona, Kewan, Tariq, Bahaj, Waled, Mori, Minako, Patel, Bhumika J., Visconte, Valeria, Maciejewski, Jaroslaw P.

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The Genomics of Myelodysplastic Syndromes: Origins of Disease Evolution, Biological Pathways, and Prognostic Implications by Awada, Hassan, Thapa, Bicky, Visconte, Valeria

“…The molecular pathogenesis of myelodysplastic syndrome (MDS) is complex due to the high rate of genomic heterogeneity. Significant advances have been made in…”
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Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation by Pagliuca, Simona, Gurnari, Carmelo, Hercus, Colin, Hergalant, Sébastien, Hong, Sanghee, Dhuyser, Adele, D’Aveni, Maud, Aarnink, Alice, Rubio, Marie Thérèse, Feugier, Pierre, Ferraro, Francesca, Carraway, Hetty E., Sobecks, Ronald, Hamilton, Betty K., Majhail, Navneet S., Visconte, Valeria, Maciejewski, Jaroslaw P.

“…Graft-versus-leukemia (GvL) reactions are responsible for the effectiveness of allogeneic hematopoietic cell transplantation as a treatment modality for…”
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Novel invariant features of Good syndrome by Gurnari, Carmelo, Durrani, Jibran, Pagliuca, Simona, Kishtagari, Ashwin, Awada, Hassan, Kerr, Cassandra M., Adema, Vera, Kongkiatkamon, Sunisa, Lichtin, Alan E., Patel, Bhumika J., Visconte, Valeria, Sekeres, Mikkael A., Cook, James R., Maciejewski, Jaroslaw P.

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