Search Results - "VIRTANEN, A"

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human by Wu, Jun, Boström, Pontus, Sparks, Lauren M., Ye, Li, Choi, Jang Hyun, Giang, An-Hoa, Khandekar, Melin, Virtanen, Kirsi A., Nuutila, Pirjo, Schaart, Gert, Huang, Kexin, Tu, Hua, van Marken Lichtenbelt, Wouter D., Hoeks, Joris, Enerbäck, Sven, Schrauwen, Patrick, Spiegelman, Bruce M.

“…Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against hypothermia and obesity. Recent data suggest that there are two…”
Get full text

Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin by Orava, Janne, Nuutila, Pirjo, Lidell, Martin E., Oikonen, Vesa, Noponen, Tommi, Viljanen, Tapio, Scheinin, Mika, Taittonen, Markku, Niemi, Tarja, Enerbäck, Sven, Virtanen, Kirsi A.

“…We investigated the metabolism of human brown adipose tissue (BAT) in healthy subjects by determining its cold-induced and insulin-stimulated glucose uptake…”
Get full text

Revising the hygroscopicity of inorganic sea salt particles by Zieger, P., Väisänen, O., Corbin, J. C., Partridge, D. G., Bastelberger, S., Mousavi-Fard, M., Rosati, B., Gysel, M., Krieger, U. K., Leck, C., Nenes, A., Riipinen, I., Virtanen, A., Salter, M. E.

“…Sea spray is one of the largest natural aerosol sources and plays an important role in the Earth’s radiative budget. These particles are inherently…”
Get full text

Diverse functions for different forms of nuclear actin by Virtanen, Jori A, Vartiainen, Maria K

“…Highlights • Nuclear actin exists in both monomeric and polymeric forms. • Actin monomers have been mainly linked to regulation of gene expression. •…”
Get full text

Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis by U Din, Mueez, Saari, Teemu, Raiko, Juho, Kudomi, Nobu, Maurer, Stefanie F., Lahesmaa, Minna, Fromme, Tobias, Amri, Ez-Zoubir, Klingenspor, Martin, Solin, Olof, Nuutila, Pirjo, Virtanen, Kirsi A.

“…Human studies suggest that a meal elevates glucose uptake in brown adipose tissue (BAT). However, in postprandial state the thermogenic activity and the…”
Get full text

Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans by Orava, Janne, Nuutila, Pirjo, Noponen, Tommi, Parkkola, Riitta, Viljanen, Tapio, Enerbäck, Sven, Rissanen, Aila, Pietiläinen, Kirsi H., Virtanen, Kirsi A.

“…Objective Inactive brown adipose tissue (BAT) may predispose to weight gain. This study was designed to measure metabolism in the BAT of obese humans, and to…”
Get full text

Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation by Li, Yongguo, Schnabl, Katharina, Gabler, Sarah-Madeleine, Willershäuser, Monja, Reber, Josefine, Karlas, Angelos, Laurila, Sanna, Lahesmaa, Minna, u Din, Mueez, Bast-Habersbrunner, Andrea, Virtanen, Kirsi A., Fromme, Tobias, Bolze, Florian, O’Farrell, Libbey S., Alsina-Fernandez, Jorge, Coskun, Tamer, Ntziachristos, Vasilis, Nuutila, Pirjo, Klingenspor, Martin

“…The molecular mediator and functional significance of meal-associated brown fat (BAT) thermogenesis remains elusive. Here, we identified the gut hormone…”
Get full text

Brown Adipose Tissue Energy Metabolism in Humans by Carpentier, André C, Blondin, Denis P, Virtanen, Kirsi A, Richard, Denis, Haman, François, Turcotte, Éric E

“…The demonstration of metabolically active brown adipose tissue (BAT) in humans primarily using positron emission tomography coupled to computed tomography…”
Get full text

Brown Adipose Reporting Criteria in Imaging STudies (BARCIST 1.0): Recommendations for Standardized FDG-PET/CT Experiments in Humans by Chen, Kong Y., Cypess, Aaron M., Laughlin, Maren R., Haft, Carol R., Hu, Houchun Harry, Bredella, Miriam A., Enerbäck, Sven, Kinahan, Paul E., Lichtenbelt, Wouter van Marken, Lin, Frank I., Sunderland, John J., Virtanen, Kirsi A., Wahl, Richard L.

“…Human brown adipose tissue (BAT) presence, metabolic activity, and estimated mass are typically measured by imaging [18F]fluorodeoxyglucose (FDG) uptake in…”
Get full text

Functional Brown Adipose Tissue in Healthy Adults by Virtanen, Kirsi A, Lidell, Martin E, Orava, Janne, Heglind, Mikael, Westergren, Rickard, Niemi, Tarja, Taittonen, Markku, Laine, Jukka, Savisto, Nina-Johanna, Enerbäck, Sven, Nuutila, Pirjo

“…Brown adipose tissue helps maintain normal body temperature in newborn humans but was thought to be absent in healthy adults. This report shows the presence of…”
Get full text

Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver: a positron emission tomography study by Honka, Miikka-Juhani, Latva-Rasku, Aino, Bucci, Marco, Virtanen, Kirsi A, Hannukainen, Jarna C, Kalliokoski, Kari K, Nuutila, Pirjo

“…Objective Insulin resistance is reflected by the rates of reduced glucose uptake (GU) into the key insulin-sensitive tissues, skeletal muscle, liver and…”
Get full text

Human brown adipose tissue [15O]O2 PET imaging in the presence and absence of cold stimulus by u Din, Mueez, Raiko, Juho, Saari, Teemu, Kudomi, Nobu, Tolvanen, Tuula, Oikonen, Vesa, Teuho, Jarmo, Sipilä, Hannu T, Savisto, Nina, Parkkola, Riitta, Nuutila, Pirjo, Virtanen, Kirsi A.

“…Purpose Brown adipose tissue (BAT) is considered a potential target for combatting obesity, as it produces heat instead of ATP in cellular respiration due to…”
Get full text

BAT Thermogenesis: Linking Shivering to Exercise by Virtanen, Kirsi A.

“…The thermogenic capacity of brown adipose tissue (BAT) in response to cold is relatively well established in humans. Several hormones and factors are involved…”
Get full text

Evidence for two types of brown adipose tissue in humans by Lidell, Martin E, Betz, Matthias J, Leinhard, Olof Dahlqvist, Heglind, Mikael, Elander, Louise, Slawik, Marc, Mussack, Thomas, Nilsson, Daniel, Romu, Thobias, Nuutila, Pirjo, Virtanen, Kirsi A, Beuschlein, Felix, Persson, Anders, Borga, Magnus, Enerbäck, Sven

“…Brown fat is a thermogenically active organ that burns energy instead of storing it and has been the focus of intense research recently in the hopes of…”
Get full text

How threats inform conservation planning-A systematic review protocol by Virtanen, Elina A, Söderholm, Maria, Moilanen, Atte

“…Conservation planning addresses the development and expansion of protected areas and requires data on for instance species, habitats, and biodiversity. Data on…”
Get full text

Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity by Gnad, Thorsten, Navarro, Gemma, Lahesmaa, Minna, Reverte-Salisa, Laia, Copperi, Francesca, Cordomi, Arnau, Naumann, Jennifer, Hochhäuser, Aileen, Haufs-Brusberg, Saskia, Wenzel, Daniela, Suhr, Frank, Jespersen, Naja Zenius, Scheele, Camilla, Tsvilovskyy, Volodymyr, Brinkmann, Christian, Rittweger, Joern, Dani, Christian, Kranz, Mathias, Deuther-Conrad, Winnie, Eltzschig, Holger K., Niemi, Tarja, Taittonen, Markku, Brust, Peter, Nuutila, Pirjo, Pardo, Leonardo, Fleischmann, Bernd K., Blüher, Matthias, Franco, Rafael, Bloch, Wilhelm, Virtanen, Kirsi A., Pfeifer, Alexander

“…The combination of aging populations with the obesity pandemic results in an alarming rise in non-communicable diseases. Here, we show that the enigmatic…”
Get full text

Humidity-dependent phase state of SOA particles from biogenic and anthropogenic precursors by Saukko, E, Lambe, A. T, Massoli, P, Koop, T, Wright, J. P, Croasdale, D. R, Pedernera, D. A, Onasch, T. B, Laaksonen, A, Davidovits, P, Worsnop, D. R, Virtanen, A

“…The physical phase state (solid, semi-solid, or liquid) of secondary organic aerosol (SOA) particles has important implications for a number of atmospheric…”
Get full text

Potential of Climate Change and Herbivory to Affect the Release and Atmospheric Reactions of BVOCs from Boreal and Subarctic Forests by Yu, H, Holopainen, J K, Kivimäenpää, M, Virtanen, A, Blande, J D

“…Compared to most other forest ecosystems, circumpolar boreal and subarctic forests have few tree species, and are prone to mass outbreaks of herbivorous…”
Get full text

Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity by Chen, Yong, Buyel, Joschka J., Hanssen, Mark J. W., Siegel, Franziska, Pan, Ruping, Naumann, Jennifer, Schell, Michael, van der Lans, Anouk, Schlein, Christian, Froehlich, Holger, Heeren, Joerg, Virtanen, Kirsi A., van Marken Lichtenbelt, Wouter, Pfeifer, Alexander

“…Brown adipose tissue (BAT) dissipates energy and its activity correlates with leanness in human adults. 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission…”
Get full text

Hygroscopic properties and cloud condensation nuclei activation of limonene-derived organosulfates and their mixtures with ammonium sulfate by Hansen, A. M. K, Hong, J, Raatikainen, T, Kristensen, K, Ylisirniö, A, Virtanen, A, Petäjä, T, Glasius, M, Prisle, N. L

“…Organosulfates have been observed as constituents of atmospheric aerosols in a wide range of environments; however their hygroscopic properties remain…”
Get full text