Search Results - "VIROSTKO, JOHN"
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Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes
Published in Frontiers in endocrinology (Lausanne) (04-12-2020)“…Magnetic resonance imaging (MRI) has the potential to improve our understanding of diabetes and improve both diagnosis and monitoring of the disease. Although…”
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2
Bayesian calibration of a stochastic, multiscale agent-based model for predicting in vitro tumor growth
Published in PLoS computational biology (01-11-2021)“…Hybrid multiscale agent-based models (ABMs) are unique in their ability to simulate individual cell interactions and microenvironmental dynamics…”
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3
Testing a new platform to screen disease-modifying therapy in type 1 diabetes
Published in PloS one (14-12-2023)“…Studies of new therapies to preserve insulin secretion in early type 1 diabetes require several years to recruit eligible subjects and to see a treatment…”
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Evaluating patient-specific neoadjuvant regimens for breast cancer via a mathematical model constrained by quantitative magnetic resonance imaging data
Published in Neoplasia (New York, N.Y.) (01-12-2020)“…The ability to accurately predict response and then rigorously optimize a therapeutic regimen on a patient-specific basis, would transform oncology. Toward…”
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5
Repeatability, reproducibility, and accuracy of quantitative mri of the breast in the community radiology setting
Published in Journal of magnetic resonance imaging (01-09-2018)“…Background Quantitative diffusion‐weighted MRI (DW‐MRI) and dynamic contrast‐enhanced MRI (DCE‐MRI) have the potential to impact patient care by providing…”
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Use of the Electronic Medical Record to Assess Pancreas Size in Type 1 Diabetes
Published in PloS one (08-07-2016)“…This study harnessed the electronic medical record to assess pancreas volume in patients with type 1 diabetes (T1D) and matched controls to determine whether…”
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Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting
Published in Breast cancer research : BCR (27-11-2021)“…The purpose of this study was to determine whether advanced quantitative magnetic resonance imaging (MRI) can be deployed outside of large, research-oriented…”
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Development of a standardized MRI protocol for pancreas assessment in humans
Published in PloS one (24-08-2021)“…Magnetic resonance imaging (MRI) has detected changes in pancreas volume and other characteristics in type 1 and type 2 diabetes. However, differences in MRI…”
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Molecular Imaging of Therapeutic Response to Epidermal Growth Factor Receptor Blockade in Colorectal Cancer
Published in Clinical cancer research (15-11-2008)“…Purpose: To evaluate noninvasive molecular imaging methods as correlative biomarkers of therapeutic efficacy of cetuximab in human colorectal cancer cell line…”
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Deep learning-based pancreas volume assessment in individuals with type 1 diabetes
Published in BMC medical imaging (05-01-2022)“…Pancreas volume is reduced in individuals with diabetes and in autoantibody positive individuals at high risk for developing type 1 diabetes (T1D). Studies…”
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Bioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse model
Published in PloS one (06-03-2013)“…We generated a mouse model (MIP-Luc-VU-NOD) that enables non-invasive bioluminescence imaging (BLI) of beta cell loss during the progression of autoimmune…”
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Characterizing Errors in Pharmacokinetic Parameters from Analyzing Quantitative Abbreviated DCE-MRI Data in Breast Cancer
Published in Tomography (Ann Arbor) (23-06-2021)“…This study characterizes the error that results when performing quantitative analysis of abbreviated dynamic contrast-enhanced magnetic resonance imaging…”
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Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-2011)“…We combined multimodal imaging (bioluminescence, X-ray computed tomography, and PET), tomographic reconstruction of bioluminescent sources, and two unique,…”
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14
Non-invasive bioluminescence imaging of β-cell function in obese-hyperglycemic [ob/ob] mice
Published in PloS one (08-09-2014)“…Type 2 diabetes results from failure of the β-cells to compensate for increased insulin demand due to abnormal levels of metabolic factors. The ob/ob(lep-/-)…”
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15
Cross-sectional imaging of the pancreas in diabetes
Published in Abdominal radiology (New York) (01-06-2024)“…Diabetes mellitus presents a global health challenge characterized by dysregulated glucose metabolism and insulin resistance. Pancreas dysfunction contributes…”
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Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging
Published in Transplantation (15-04-2005)“…Pancreatic islet transplantation is an emerging therapy for type 1 diabetes, but it is difficult to assess islets after transplantation and thus to design…”
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Large language models in radiology: Fluctuating performance and decreasing discordance over time
Published in European journal of radiology (01-01-2025)“…•LLMs show > 70 % accuracy on radiology exams with fluctuating performance over 3 months.•GPT-4, the overall best performer, actually demonstrates decreasing…”
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Disparities in the Demographic Composition of The Cancer Imaging Archive
Published in Radiology. Imaging cancer (01-01-2024)“…Purpose To characterize the demographic distribution of The Cancer Imaging Archive (TCIA) studies and compare them with those of the U.S. cancer population…”
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Changes in Pancreas Volume in Living Donor Liver Transplant Recipients
Published in Transplantation (01-10-2024)“…Metabolic factors have a significant role in the morbidity and mortality associated with chronic liver disease. The pancreas has a central role in metabolism…”
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Recent trends in the age at diagnosis of colorectal cancer in the US National Cancer Data Base, 2004‐2015
Published in Cancer (01-11-2019)“…Background The incidence of colorectal cancer (CRC) in adults younger than 50 years has increased in the United States over the past decades according to…”
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