Search Results - "VINOGRADOVA, T. V"
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PDX1: A unique pancreatic master regulator constantly changes its functions during embryonic development and progression of pancreatic cancer
Published in Biochemistry (Moscow) (01-08-2017)“…Multifunctional activity of the PDX1 gene product is reviewed. The PDX1 protein is unique in that being expressed exclusively in the pancreas it exhibits…”
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Cancer Stem Cells: Plasticity Works against Therapy
Published in Actanaturae (01-10-2015)“…Great successes in identification and deciphering of mechanisms of the adult stem cells regulation have given rise to the idea that stem cells can also…”
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Functional significance of a putative Sp1 transcription factor binding site in the survivin gene promoter
Published in Biochemistry (Moscow) (01-11-2008)“…We sequenced 1500-bp genomic DNA regions upstream from the survivin gene (BIRC5). DNA was isolated from human placenta and tumors of patients with diagnosed…”
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Evaluation of the toxic effects evoked by the transient expression of protease genes from human pathogens in HEK293 cells
Published in Applied biochemistry and microbiology (01-12-2013)“…A method for the in vitro evaluation of the toxic effects occurring in human cell lines upon the expression of genes from a range of pathogens is proposed. The…”
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Core promoters as an example of the effect of whole-genome information on the evolution of views on molecular mechanisms of vital activity
Published in Molecular biology (New York) (01-10-2010)“…Complete DNA sequences of many animal genomes combined with the information on new classes of regulatory elements within the regions conventionally viewed as…”
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Downregulation of RBSP3/CTDSPL, NPRL2/G21, RASSF1A, ITGA9, HYAL1, and HYAL2 in non-small cell lung cancer
Published in Molecular biology (New York) (01-12-2008)“…Chromosomal and genome abnormalities of 3p are frequent in many epithelial tumors, including lung cancer. Several critical regions with a high frequency of…”
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Influtnce analysis of 09Г2С and 30MnB5 steels thermo cyclic treatment on strength characteristics of road construction machines working bodies
Published in Vestnik SibADI (Online) (20-05-2021)“…Introduction. The ways of increasing the reliability of road construction machinery operation are considered. As a result, an option is proposed to replace the…”
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Role of Cardiac Glycosides in Regulation of the Growth of Retinal Tissue Explants
Published in Bulletin of experimental biology and medicine (01-12-2008)“…We studied the role of cardiac glycosides in the regulation of the growth of retinal tissue explants from 10-12-day-old chicken embryos in organotypic culture…”
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About pathogenesis of depressive state of central nervous system in premature infants
Published in Детские инфекции (Москва) (21-03-2022)“…The study of the neurological status and heart rate variability (HRV) of 65 premature newborns was carried out, of which 25 children had no symptoms of central…”
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Functional analysis of the HERV-K LTR residing in the KIAA1245/NBPF subfamily genes
Published in Molecular biology (New York) (01-08-2010)“…Long terminal repeats (LTRs) of human endogenous retroviruses (HERVs) might affect transcription regulation of neighboring genes. In our previous study, we…”
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Effects of the Treatment of Mothers with Multiple Sclerosis Using Disease-Modifying Drugs on Child Development
Published in Neuroscience and behavioral physiology (01-09-2018)“…Objectives. To evaluate the effects of treating mothers with multiple sclerosis disease-modifying drugs (MS DMD) on the physical and mental development of…”
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Correlation between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer
Published in Doklady. Biochemistry and biophysics (01-07-2018)“…The mRNA content of the transcription factors KLF5 and ZEB1 was studied in pancreatic tumor tissues and in fetal and normal pancreas. Transcription of these…”
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Pediatric autoimmune neuropsychiatric disorder associated with Streptococcal infection (PANDAS syndrome): real-world practice and clinical case
Published in Детские инфекции (Москва) (08-10-2019)“…Group A beta-hemolytic streptococcus is one of the most important infectious agents leading to both direct damage to organs, and to various cross-reactions…”
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Pioneer transcription factors in normal development and carcinogenesis
Published in Russian journal of bioorganic chemistry (01-11-2015)“…Pioneer transcription factors constitute a heterogeneous group of regulatory animal proteins that, unlike other transcription factors, are able to recognize…”
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Cellular and molecular phenotypes of proliferating stromal cells from human carcinomas
Published in British journal of cancer (11-05-2010)“…Background: Stromal cells are a functionally important component of human carcinomas. The aim of this study was to obtain and characterise primary cultures of…”
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Master transcription regulators specifying cell-lineage fates in development as possible therapeutic targets in oncology
Published in Russian journal of genetics (01-11-2015)“…The transformation of normal precursors into cancer cells is an intricately regulated, multistep process. The master regulatory genes that play a crucial role…”
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Master Transcription Regulators Specifying Cell-Lineage Fates in Development As Possible Therapeutic Targets in Oncology
Published in Genetika (01-11-2015)“…The transformation of normal precursors into cancer cells is an intricately regulated, multistep process. The master regulatory genes that play a crucial role…”
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Dependence of expression of regulatory master genes of embryonic development in pancreatic cancer cells on the intracellular concentration of the master regulator PDX1
Published in Doklady. Biochemistry and biophysics (01-07-2017)“…Exogenous expression of the gene encoding the pancreatic master regulator PDX1 in cell lines with different degrees of differentiation of pancreatic cancer…”
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Quantitative comparison of gene co-expression in a bicistronic vector harboring IRES or coding sequence of porcine teschovirus 2A peptide
Published in Russian journal of bioorganic chemistry (01-07-2013)“…In biotechnology, simultaneous expression of more than one target gene is often required. Multicistronic vectors encoding several proteins are being actively…”
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The NOLA2 and RPS3A genes as highly informative markers of human squamous cell carcinoma of lung
Published in Russian journal of bioorganic chemistry (01-03-2005)“…cDNA libraries enriched with sequences that are differentially transcribed in normal and tumor tissues were prepared using the subtractive hybridization of…”
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