Search Results - "VINOGRADOV, Sergei A."

Oxyphor 2P: A High-Performance Probe for Deep-Tissue Longitudinal Oxygen Imaging by Esipova, Tatiana V., Barrett, Matthew J.P., Erlebach, Eva, Masunov, Artëm E., Weber, Bruno, Vinogradov, Sergei A.

“…Quantitative imaging of oxygen distributions in tissue can provide invaluable information about metabolism in normal and diseased states. Two-photon…”
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Direct measurement of local oxygen concentration in the bone marrow of live animals by Spencer, Joel A., Ferraro, Francesca, Roussakis, Emmanuel, Klein, Alyssa, Wu, Juwell, Runnels, Judith M., Zaher, Walid, Mortensen, Luke J., Alt, Clemens, Turcotte, Raphaël, Yusuf, Rushdia, Côté, Daniel, Vinogradov, Sergei A., Scadden, David T., Lin, Charles P.

“…Here, using two-photon phosphorescence lifetime microscopy, the local oxygen tension in the bone marrow of live mice is found to be quite low, with…”
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Correlation Between Intraluminal Oxygen Gradient and Radial Partitioning of Intestinal Microbiota by Albenberg, Lindsey, Esipova, Tatiana V, Judge, Colleen P, Bittinger, Kyle, Chen, Jun, Laughlin, Alice, Grunberg, Stephanie, Baldassano, Robert N, Lewis, James D, Li, Hongzhe, Thom, Stephen R, Bushman, Frederic D, Vinogradov, Sergei A, Wu, Gary D

“…Background & Aims The gut microbiota is a complex and densely populated community in a dynamic environment determined by host physiology. We investigated how…”
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Live-animal imaging of native haematopoietic stem and progenitor cells by Christodoulou, Constantina, Spencer, Joel A., Yeh, Shu-Chi A., Turcotte, Raphaël, Kokkaliaris, Konstantinos D., Panero, Riccardo, Ramos, Azucena, Guo, Guoji, Seyedhassantehrani, Negar, Esipova, Tatiana V., Vinogradov, Sergei A., Rudzinskas, Sarah, Zhang, Yi, Perkins, Archibald S., Orkin, Stuart H., Calogero, Raffaele A., Schroeder, Timm, Lin, Charles P., Camargo, Fernando D.

“…The biology of haematopoietic stem cells (HSCs) has predominantly been studied under transplantation conditions 1 , 2 . It has been particularly challenging to…”
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Microbes vs. chemistry in the origin of the anaerobic gut lumen by Friedman, Elliot S., Bittinger, Kyle, Esipova, Tatiana V., Hou, Likai, Chau, Lillian, Jiang, Jack, Mesaros, Clementina, Lund, Peder J., Liang, Xue, FitzGerald, Garret A., Goulian, Mark, Lee, Daeyeon, Garcia, Benjamin A., Blair, Ian A., Vinogradov, Sergei A., Wu, Gary D.

“…The succession from aerobic and facultative anaerobic bacteria to obligate anaerobes in the infant gut along with the differences between the compositions of…”
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Quantification of Oxygen Depletion During FLASH Irradiation In Vitro and In Vivo by Cao, Xu, Zhang, Rongxiao, Esipova, Tatiana V., Allu, Srinivasa Rao, Ashraf, Ramish, Rahman, Mahbubur, Gunn, Jason R., Bruza, Petr, Gladstone, David J., Williams, Benjamin B., Swartz, Harold M., Hoopes, P. Jack, Vinogradov, Sergei A., Pogue, Brian W.

“…Delivery of radiation at ultrahigh dose rates (UHDRs), known as FLASH, has recently been shown to preferentially spare normal tissues from radiation damage…”
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CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere by Falk, Samantha J., Guo, Lucie Y., Sekulic, Nikolina, Smoak, Evan M., Mani, Tomoyasu, Logsdon, Glennis A., Gupta, Kushol, Jansen, Lars E. T., Van Duyne, Gregory D., Vinogradov, Sergei A., Lampson, Michael A., Black, Ben E.

“…Inheritance of each chromosome depends upon its centromere. A histone H3 variant, centromere protein A (CENP-A), is essential for epigenetically marking…”
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Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue by Ruvinskaya, Svetlana, Lo, Eng H, Vinogradov, Sergei A, Devor, Anna, Arai, Ken, Sakad i, Sava, Roussakis, Emmanuel, Mandeville, Emiri T, Srinivasan, Vivek J, Boas, David A, Yaseen, Mohammad A

“…Two-photon excitation of a phosphorescent nanoprobe that is quenched by molecular oxygen permits high-resolution measurements of oxygen in both the vasculature…”
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Spin–Orbit versus Hyperfine Coupling-Mediated Intersystem Crossing in a Radical Pair by May, Sam R., Climent, Clàudia, Tao, Zhen, Vinogradov, Sergei A., Subotnik, Joseph E.

“…While spin–orbit coupling (SOC) is typically the dominant interaction that couples singlet and triplet states within individual chromophores, hyperfine…”
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Two New “Protected” Oxyphors for Biological Oximetry: Properties and Application in Tumor Imaging by Esipova, Tatiana V, Karagodov, Alexander, Miller, Joann, Wilson, David F, Busch, Theresa M, Vinogradov, Sergei A

“…We report the synthesis, calibration, and examples of application of two new phosphorescent probes, Oxyphor R4 and Oxyphor G4, optimized specifically for in…”
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Electrospun Fiber Mesh for High-Resolution Measurements of Oxygen Tension in Cranial Bone Defect Repair by Schilling, Kevin, El Khatib, Mirna, Plunkett, Shane, Xue, Jiajia, Xia, Younan, Vinogradov, Sergei A, Brown, Edward, Zhang, Xinping

“…Tissue oxygenation is one of the key determining factors in bone repair and bone tissue engineering. Adequate tissue oxygenation is essential for survival and…”
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Gold Tris(carboxyphenyl)corroles as Multifunctional Materials: Room Temperature Near-IR Phosphorescence and Applications to Photodynamic Therapy and Dye-Sensitized Solar Cells by Alemayehu, Abraham B, Day, Nicholas U, Mani, Tomoyasu, Rudine, Alexander B, Thomas, Kolle E, Gederaas, Odrun A, Vinogradov, Sergei A, Wamser, Carl C, Ghosh, Abhik

“…Two amphiphilic corroles5,10,15-tris­(3-carboxy­phenyl)­corrole (H3[mTCPC]) and 5,10,15-tris­(4-carboxy­phenyl)­corrole (H3[pTCPC])and their gold complexes…”
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Magnetic Field Effects on Triplet–Triplet Annihilation in Solutions: Modulation of Visible/NIR Luminescence by Mani, Tomoyasu, Vinogradov, Sergei A

“…Photon upconversion based on sensitized triplet–triplet annihilation (TTA) presents interest for such areas as photovoltaics and imaging. Usually, energy…”
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More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction by Li, Baoqiang, Esipova, Tatiana V, Sencan, Ikbal, Kılıç, Kıvılcım, Fu, Buyin, Desjardins, Michele, Moeini, Mohammad, Kura, Sreekanth, Yaseen, Mohammad A, Lesage, Frederic, Østergaard, Leif, Devor, Anna, Boas, David A, Vinogradov, Sergei A, Sakadžić, Sava

“…Our understanding of how capillary blood flow and oxygen distribute across cortical layers to meet the local metabolic demand is incomplete. We addressed this…”
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Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy by Cao, Xu, Rao Allu, Srinivasa, Jiang, Shudong, Jia, Mengyu, Gunn, Jason R., Yao, Cuiping, LaRochelle, Ethan P., Shell, Jennifer R., Bruza, Petr, Gladstone, David J., Jarvis, Lesley A., Tian, Jie, Vinogradov, Sergei A., Pogue, Brian W.

“…Hypoxia in solid tumors is thought to be an important factor in resistance to therapy, but the extreme microscopic heterogeneity of the partial pressures of…”
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Endothermic and Exothermic Energy Transfer Made Equally Efficient for Triplet–Triplet Annihilation Upconversion by Isokuortti, Jussi, Allu, Srinivasa Rao, Efimov, Alexander, Vuorimaa-Laukkanen, Elina, Tkachenko, Nikolai V, Vinogradov, Sergei A, Laaksonen, Timo, Durandin, Nikita A

“…Expanding the anti-Stokes shift for triplet–triplet annihilation upconversion (TTA-UC) systems with high quantum yields without compromising power density…”
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In vivo imaging and analysis of cerebrovascular hemodynamic responses and tissue oxygenation in the mouse brain by Kisler, Kassandra, Lazic, Divna, Sweeney, Melanie D, Plunkett, Shane, El Khatib, Mirna, Vinogradov, Sergei A, Boas, David A, Sakadži´, Sava, Zlokovic, Berislav V

“…A series of diverse in vivo imaging protocols for evaluating hemodynamic response and tissue oxygenation in mouse models of neurological and vascular disorders…”
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Frontiers in Optical Imaging of Cerebral Blood Flow and Metabolism by Devor, Anna, Sakadžić, Sava, Srinivasan, Vivek J, Yaseen, Mohammad A, Nizar, Krystal, Saisan, Payam A, Tian, Peifang, Dale, Anders M, Vinogradov, Sergei A, Franceschini, Maria Angela, Boas, David A

“…In vivo optical imaging of cerebral blood flow (CBF) and metabolism did not exist 50 years ago. While point optical fluorescence and absorption measurements of…”
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Dendritic upconverting nanoparticles enable in vivo multiphoton microscopy with low-power continuous wave sources by Esipova, Tatiana V., Ye, Xingchen, Collins, Joshua E., Sakadžić, Sava, Mandeville, Emiri T., Murray, Christopher B., Vinogradov, Sergei A.

“…We report a group of optical imaging probes, comprising upconverting lanthanide nanoparticles (UCNPs) and polyanionic dendrimers. Dendrimers with rigid cores…”
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Disruption of intestinal oxygen balance in acute colitis alters the gut microbiome by Zong, Wenjing, Friedman, Elliot S, Allu, Srinivasa Rao, Firrman, Jenni, Tu, Vincent, Daniel, Scott G, Bittinger, Kyle, Liu, LinShu, Vinogradov, Sergei A, Wu, Gary D

“…The juxtaposition of well-oxygenated intestinal colonic tissue with an anerobic luminal environment supports a fundamentally important relationship that is…”
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