Search Results - "VINCZAN, A"

The cytotoxicity of melphalan and its relationship to pH, hypoxia and drug uptake by Skarsgard, L D, Skwarchuk, M W, Vinczan, A, Kristl, J, Chaplin, D J

“…In the present in vitro studies we examined the effect of hypoxia and acidic pH, two important consequences of reduced blood flow in vivo, on the cytotoxicity…”
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The effect of pH on the aerobic and hypoxic cytotoxicity of SR4233 in HT-29 cells by SKARSGARD, L. D, SKWARCHUK, M. W, VINCZAN, A, CHAPLIN, D. J

“…We have observed that low pH can substantially potentiate the cytotoxic effect of the bioreductive drug SR4233 in aerobic HT-29 human tumour cells. No such…”
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Cytotoxic effect of RB 6145 in human tumour cell lines: dependence on hypoxia, extra- and intracellular pH and drug uptake by SKARSGARD, L. D, ACHESON, D. K, VINCZAN, A, WOUTERS, B. G, HEINRICHS, B. E, LOBLAW, D. A, MINCHINTON, A. I, CHAPLIN, D. J

“…Low pH and hypoxia are a common feature of many solid tumours. This study examined the effect of these two conditions on the cytotoxic properties of the…”
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The effect of low pH and hypoxia on the cytotoxic effects of SR4233 and mitomycin C in vitro by Skarsgard, L D, Vinczan, A, Skwarchuk, M W, Chaplin, D J

“…We examined the effect of acidic pH and hypoxia on the cytotoxicity of SR4233 and mitomycin C in vitro. The importance of tumor microenvironment to the…”
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The effect of hypoxia and low pH on the cytotoxicity of chlorambucil by Skarsgard, L D, Chaplin, D J, Wilson, D J, Skwarchuk, M W, Vinczan, A, Kristl, J

“…Studies with mouse tumors have shown that the effectiveness of certain chemotherapeutic agents can be enhanced if they are used in appropriate combination with…”
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