Search Results - "VINATZER, Ursula"
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The Pro allele of the p53 codon 72 polymorphism is associated with decreased intratumoral expression of BAX and p21, and increased breast cancer risk
Published in PloS one (10-10-2012)“…The TP53 Arg72Pro polymorphism encodes two p53 variants with different biochemical properties. Here we investigated the impact of this polymorphism on the…”
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Mucosa-Associated Lymphoid Tissue Lymphoma: Novel Translocations Including Rearrangements of ODZ2, JMJD2C, and CNN3
Published in Clinical cancer research (15-10-2008)“…Purpose: The well-known translocations identified in MALT lymphomas include t(11;18)/ API2-MALT1 , t(1;14)/ IGH-BCL10 , and t(14;18)/ IGH-MALT1 . Molecular…”
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Novel Clinically Relevant Genes in Gastrointestinal Stromal Tumors Identified by Exome Sequencing
Published in Clinical cancer research (01-10-2013)“…Chromosomal gains and losses resulting in altered gene dosage are known to be recurrent in gastrointestinal stromal tumors (GIST). The aim of our study was the…”
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Expression of HER2 and the Coamplified Genes GRB7 and MLN64 in Human Breast Cancer: Quantitative Real-time Reverse Transcription-PCR as a Diagnostic Alternative to Immunohistochemistry and Fluorescence In situ Hybridization
Published in Clinical cancer research (01-12-2005)“…Purpose: Accurate testing of HER2 is centrally important for breast cancer therapy and prognosis. Immunohistochemistry (IHC) and fluorescence in situ…”
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Impact of constitutive IGF1/IGF2 stimulation on the transcriptional program of human breast cancer cells
Published in Carcinogenesis (New York) (01-01-2007)“…Insulin-like growth factor (IGF) signaling is a key regulator of breast development and breast cancer. We have analyzed the expression of the IGF signaling…”
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Regulation of the expression of the oncogene EVI1 through the use of alternative mRNA 5′-ends
Published in Gene (15-08-2005)“…The EVI1 gene plays important roles in development and leukemogenesis. Recently, human EVI1 has been shown to give rise to at least six different mRNA variants…”
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Biochemical and Genetic Testing of GAA in Over 30.000 Symptomatic Patients Suspected to Be Affected With Pompe Disease
Published in Human mutation (01-01-2024)“…Pompe disease (PD) is a rare autosomal recessive lysosomal disorder caused by loss‐of‐function of the α ‐glucosidase ( GAA ) gene. The deficient GAA enzyme…”
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Comparative Expression Analysis of the Antagonistic Transcription Factors EVI1 and MDS1-EVI1 in Murine Tissues and duringin VitroHematopoietic Differentiation
Published in Biochemical and biophysical research communications (01-11-1998)“…An alternative form of the transcription factor EVI1, MDS1-EVI1, which previously had been believed to exist only in the context of leukemic fusion mRNAs, has…”
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MAPKAP Kinase 2 Overexpression Influences Prognosis in Gastrointestinal Stromal Tumors and Associates with Copy Number Variations on Chromosome 1 and Expression of p38 MAP Kinase and ETV1
Published in Clinical cancer research (01-04-2012)“…ETV1 has been proposed to be activated by KIT mutations in gastrointestinal stromal tumors (GIST). The aim of the study was to evaluate the clinical role of…”
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Global and single gene DNA methylation in umbilical cord blood cells after elective caesarean: a pilot study
Published in European journal of obstetrics & gynecology and reproductive biology (01-08-2014)“…Abstract Objective To evaluate global and single gene methylation patterns as a sign for epigenetic modulation of the immune system in infants born by elective…”
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t(11;14)(q23;q32) involving IGH and DDX6 in nodal marginal zone lymphoma
Published in Genes chromosomes & cancer (01-01-2013)“…Nodal marginal zone lymphoma (NMZL) is a primary nodal B‐cell lymphoma that shares morphological and immunophenotypic characteristics with extranodal and…”
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Growth phase-regulated induction of Salmonella-induced macrophage apoptosis correlates with transient expression of SPI-1 genes
Published in Journal of bacteriology (01-06-1999)“…Invasive Salmonella has been reported to induce apoptosis in a fraction of infected macrophages within 2 to 14 h from the time of infection by a mechanism…”
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The leukaemia‐associated transcription factors EVI‐1 and MDS1/EVI1 repress transcription and interact with histone deacetylase
Published in British journal of haematology (01-09-2001)“…EVI‐1 and its variant form, MDS1/EVI1, have been reported to act in an antagonistic manner and be differentially regulated in samples from patients with acute…”
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t(3;14)(P14.1;Q32) Involving IGH and FOXP1 Is a Recurrent Chromosomal Aberration in MALT Lymphoma
Published in Blood (16-11-2004)“…Translocations t(11;18)(q21;q21), t(14;18)(q32;q21), and t(1;14)(p22;q32) are known to occur in MALT lymphoma. In a patient with MALT lymphoma of the thyroid a…”
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Quantitative comparison of the expression of EVI1 and its presumptive antagonist, MDS1/EVI1, in patients with myeloid leukemia
Published in Genes chromosomes & cancer (01-01-2003)“…The EVI1 gene in chromosome band 3q26 exhibits a number of properties consistent with a role as an oncogene, and its expression is activated in most myeloid…”
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Transcription Factor GATA-2 Gene Is Located Near 3q21 Breakpoints in Myeloid Leukemia
Published in Biochemical and biophysical research communications (24-06-2000)“…Rearrangements affecting chromosome band 3q21 are observed in a subgroup of patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)…”
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Comparative expression analysis of the antagonistic transcription factors EVI1 and MDS1-EVI1 in murine tissues and during in vitro hematopoietic differentiation
Published in Biochemical and biophysical research communications (27-11-1998)“…An alternative form of the transcription factor EVI1, MDS1-EVI1, which previously had been believed to exist only in the context of leukemic fusion mRNAs, has…”
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Growth Phase-Regulated Induction ofSalmonella-Induced Macrophage Apoptosis Correlates with Transient Expression of SPI-1 Genes
Published in Journal of Bacteriology (01-06-1999)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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