Search Results - "VILLAR, Ana"

Organizational innovation as an enabler of technological innovation capabilities and firm performance by Camisón, César, Villar-López, Ana

“…This study assesses the relationship between organizational innovation and technological innovation capabilities, and analyzes their effect on firm performance…”
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Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX by Lacoste, Nicolas, Woolfe, Adam, Tachiwana, Hiroaki, Garea, Ana Villar, Barth, Teresa, Cantaloube, Sylvain, Kurumizaka, Hitoshi, Imhof, Axel, Almouzni, Geneviève

“…Centromeres are essential for ensuring proper chromosome segregation in eukaryotes. Their definition relies on the presence of a centromere-specific H3 histone…”
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An examination of the relationship between manufacturing flexibility and firm performance: The mediating role of innovation by Camison, Cesar, Lopez, Ana Villar

“…Purpose - The purpose of this paper is to test the mediating role of three types of innovation (product, process, and organizational) in the relationship…”
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PARP1 expression predicts PARP inhibitor sensitivity and correlates with metastatic potential and overall survival in melanoma by Fröhlich, Lisa Marie, Villar‐Miyar, Ana, Heintze, Tamara, Sauer, Birgit, Schittek, Birgit

“…Metastatic melanoma is still a difficult‐to‐treat cancer type owing to its frequent resistance mechanisms to targeted and immunotherapy. Therefore, we aimed to…”
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Epigenetic alterations of TGFβ and its main canonical signaling mediators in the context of cardiac fibrosis by Algeciras, Luis, Palanca, Ana, Maestro, David, RuizdelRio, Jorge, Villar, Ana V.

“…Cardiac fibrosis is a pathological process that presents a continuous overproduction of extracellular matrix (ECM) components in the myocardium, which…”
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Long‐term outcomes in chronic hypersensitivity pneumonitis by Ojanguren, Iñigo, Morell, Ferran, Ramón, María‐Antonia, Villar, Ana, Romero, Christian, Cruz, María Jesús, Muñoz, Xavier

“…Introduction The objective of this study was to analyze mortality, possible predictors of long‐term survival, and health‐related quality of life of a large…”
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Clinical and economic burden of acute exacerbations of idiopathic pulmonary fibrosis: a prospective observational study in Spain (OASIS study) by Gómez, Ana Villar, Rodríguez-Nieto, M J, Cano-Jiménez, E, Ortiz, A Romero, Morros, M, Ramon, A, Armengol, S

“…Idiopathic pulmonary fibrosis (IPF) is a fatal progressive lung disease entailing significant impairment in health-related quality of life (HRQoL) and high…”
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Chronic hypersensitivity pneumonitis in patients diagnosed with idiopathic pulmonary fibrosis: a prospective case-cohort study by Morell, Ferran, Prof, Villar, Ana, MD, Montero, María-Ángeles, MD, Muñoz, Xavier, MD, Colby, Thomas V, Prof, Pipvath, Sudhakar, MD, Cruz, María-Jesús, MD, Raghu, Ganesh, Prof

“…Summary Background The clinical features of idiopathic pulmonary fibrosis (IPF) and chronic hypersensitivity pneumonitis can be indistinguishable; the need to…”
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Impact of the SARS-CoV-2 pandemic on pancreatic cancer: diagnosis and short-term survival by Tejedor-Tejada, Javier, Gómez-Díez, César, Robles Gaitero, Samuel, Villar Caamaño, Ana, Hermida Pérez, Benito, Olmos, Jose Manuel, Álvarez Álvarez, Aránzazu, Tojo González, Rafael

“…The COVID-19 pandemic has delayed medical consultation, possibly leading to the diagnosis of gastrointestinal cancer. The aim of the study was to analyze the…”
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Photoinduced Decarboxylative Radical Addition Reactions for Late Stage Functionalization of Peptide Substrates by Fernandez‐Rodriguez, Patricia, Legros, Fabien, Maier, Thomas, Weber, Angelika, Méndez, María, Derdau, Volker, Hessler, Gerhard, Kurz, Michael, Villar‐Garea, Ana, Ruf, Sven

“…Photoredox chemistry has greatly stimulated the application of radical based transformations in medicinal chemistry and early drug discovery in recent years…”
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BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery by Merino, David, Villar, Ana V, García, Raquel, Tramullas, Mónica, Ruiz, Luis, Ribas, Catalina, Cabezudo, Sofía, Nistal, Juan Francisco, Hurlé, María A

“…TGF-β regulates tissue fibrosis: TGF-β promotes fibrosis, whereas bone morphogenetic protein (BMP)-7 is antifibrotic. To demonstrate that (i) left ventricular…”
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Fibroblast-derived extracellular vesicles as trackable efficient transporters of an experimental nanodrug with fibrotic heart and lung targeting by RuizdelRio, Jorge, Guedes, Gabriela, Novillo, Danielle, Lecue, Elena, Palanca, Ana, Cortajarena, Aitziber L, Villar, Ana V

“…The discovery of extracellular vesicles (EVs) as efficient exogenous biotransporters of therapeutic agents into cells across biological membranes is an…”
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Engineering multifunctional metal/protein hybrid nanomaterials as tools for therapeutic intervention and high-sensitivity detection by Aires, Antonio, Maestro, David, Ruiz del Rio, Jorge, Palanca, Ana R, Lopez-Martinez, Elena, Llarena, Irantzu, Geraki, Kalotina, Sanchez-Cano, Carlos, Villar, Ana V, Cortajarena, Aitziber L

“…Protein-based hybrid nanomaterials have recently emerged as promising platforms to fabricate tailored multifunctional biologics for biotechnological and…”
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Extracellular heat shock protein 90 binding to TGFβ receptor I participates in TGFβ-mediated collagen production in myocardial fibroblasts by García, Raquel, Merino, David, Gómez, Jenny M, Nistal, J Francisco, Hurlé, María A, Cortajarena, Aitziber L, Villar, Ana V

“…The pathological remodeling heart shows an increase in left ventricular mass and an excess of extracellular matrix deposition that can over time cause heart…”
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Design and optimization of self-nanoemulsifying drug delivery systems (SNEDDS) for enhanced dissolution of gemfibrozil by Villar, Ana Maria Sierra, Naveros, Beatriz Clares, Campmany, Ana Cristina Calpena, Trenchs, Monserrat Aróztegui, Rocabert, Coloma Barbé, Bellowa, Lyda Halbaut

“…Self-nanoemulsifying drug delivery systems of gemfibrozil were developed under Quality by Design approach for improvement of dissolution and oral absorption…”
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Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients by Villar, Ana V, García, Raquel, Merino, David, Llano, Miguel, Cobo, Manuel, Montalvo, Cecilia, Martín-Durán, Rafael, Hurlé, María A, Nistal, J. Francisco

“…Abstract Background Various human cardiovascular pathophysiological conditions associate aberrant expression of microRNAs (miRNAs) and circulating miRNAs are…”
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Usefulness of FDG PET/CT in the management of tuberculosis by Sánchez-Montalvá, Adrián, Barios, Marta, Salvador, Fernando, Villar, Ana, Tórtola, Teresa, Molina-Morant, Daniel, Lorenzo-Bosquet, Carles, Espinosa-Pereiro, Juan, Molina, Israel

“…The aim of our study is to describe the FDG-PET/CT findings in patients with tuberculosis and to correlate them with the patient's prognosis. We…”
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Profibrotic Role of Inducible Heat Shock Protein 90α Isoform in Systemic Sclerosis by RuizdelRio, Jorge, Muñoz, Pedro, Carreira, Patricia, Maestro, David, Pablos, Jose L., Palanca, Ana, Merino, Jesus, Serrano-Mollar, Anna, Merino, Ramon, Tamayo, Esther, Lopez-Hoyos, Marcos, Diaz-Gonzalez, Federico, Martinez-Taboada, Victor, Villar, Ana V.

“…Systemic sclerosis (SSc) is an autoimmune disease that affects skin and multiple internal organs. TGF-β, a central trigger of cutaneous fibrosis, activates…”
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EEG Waveform Analysis of P300 ERP with Applications to Brain Computer Interfaces by Ramele, Rodrigo, Villar, Ana Julia, Santos, Juan Miguel

“…The Electroencephalography (EEG) is not just a mere clinical tool anymore. It has become the de-facto mobile, portable, non-invasive brain imaging sensor to…”
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Androgens contribute to sex differences in myocardial remodeling under pressure overload by a mechanism involving TGF-β by Montalvo, Cecilia, Villar, Ana V, Merino, David, García, Raquel, Ares, Miguel, Llano, Miguel, Cobo, Manuel, Hurlé, María A, Nistal, J Francisco

“…In clinical studies, myocardial remodeling in aortic valve stenosis appears to be more favorable in women than in men, even after menopause. In the present…”
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