Search Results - "VILLA, R"
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1
The Neurobiology of Depression: an Integrated Overview from Biological Theories to Clinical Evidence
Published in Molecular neurobiology (01-09-2017)“…Depressive disorders are heterogeneous diseases, and the complexity of symptoms has led to the formulation of several aethiopathological hypotheses. This…”
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2
Onset and Evolution of Southern Annular Mode-Like Changes at Centennial Timescale
Published in Scientific reports (22-02-2018)“…The Southern Westerly Winds (SWW) are the surface expression of geostrophic winds that encircle the southern mid-latitudes. In conjunction with the Southern…”
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3
Blood flow restricted resistance training in older adults at risk of mobility limitations
Published in Experimental gerontology (01-12-2017)“…High-load resistance training (HL) may be contraindicated in older adults due to pre-existing health conditions (e.g. osteoarthritis). Low-load blood flow…”
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4
An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers
Published in Cancer cell (14-11-2016)“…Small-molecule inhibitors targeting growth factor receptors have failed to show efficacy for brain cancers, potentially due to their inability to achieve…”
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5
mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc
Published in Cell metabolism (05-11-2013)“…Aerobic glycolysis (the Warburg effect) is a core hallmark of cancer, but the molecular mechanisms underlying it remain unclear. Here, we identify an…”
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6
Color tunable pressure sensors based on polymer nanostructured membranes for optofluidic applications
Published in Scientific reports (01-03-2019)“…We demonstrate an integrated optical pressure sensing platform for multiplexed optofluidics applications. The sensing platform consists in an array of…”
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7
Characterisation of food service establishment wastewater and its implication for treatment
Published in Journal of environmental management (15-12-2019)“…Essential for the selection of a reliable treatment system is the characterisation of the effluent to treat. Kitchen wastewater (KWW) from food service…”
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8
Understanding why fat, oil and grease (FOG) bioremediation can be unsuccessful
Published in Journal of environmental management (01-08-2020)“…Commercial kitchen wastewaters are typically strong organic and fat-rich effluents, often identified as major contributors to fatberg formation and associated…”
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9
Reactivity in cement pastes bearing fine fraction concrete and glass from construction and demolition waste: Microstructural analysis of viability
Published in Cement and concrete research (01-10-2021)“…Converting construction and demolition waste (CDW) into secondary raw materials is one of the priorities of environmental policy and circular economy strategy…”
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10
Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
Published in Cell metabolism (03-09-2019)“…Advances in DNA sequencing technologies have reshaped our understanding of the molecular basis of cancer, providing a precise genomic view of tumors…”
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11
New scientific evidence of the effect of high temperatures and long curing times on MK-blended cement paste mineralogy
Published in Cement and concrete research (01-02-2022)“…This article reports new scientific evidence on the hydrated phases present in blended cement pastes formulated with 10%, 20% or 25% metakaolin (MK) and stored…”
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12
mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
Published in Molecular cell (06-07-2017)“…Mutations in cancer reprogram amino acid metabolism to drive tumor growth, but the molecular mechanisms are not well understood. Using an unbiased proteomic…”
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13
Southern Annular Mode-like changes in southwestern Patagonia at centennial timescales over the last three millennia
Published in Nature communications (10-07-2014)“…Late twentieth-century instrumental records reveal a persistent southward shift of the Southern Westerly Winds during austral summer and autumn associated with…”
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14
EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling
Published in Molecular cell (15-10-2015)“…Epidermal growth factor receptor (EGFR) gene amplification and mutations are the most common oncogenic events in glioblastoma (GBM), but the mechanisms by…”
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15
Zika, or the burden of uncertainty
Published in Clinica terapeutica (2016)“…In the first phases of an infectious outbreak, health authorities have to face the challenge of communicating uncertainty. Just when the attention of the…”
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16
Hydrogen sulfide and sulfaceutic or sulfanutraceutic agents: Classification, differences and relevance in preclinical and clinical studies
Published in Pharmacological research (01-10-2023)“…Hydrogen sulfide (H2S) has been extensively studied as a signal molecule in the body for the past 30 years. Researchers have conducted studies using both…”
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17
Seawater effect on durability of ternary cements. Synergy of chloride and sulphate ions
Published in Composites. Part B, Engineering (01-03-2013)“…The durability of a new cementing composite (ternary cement pastes), containing thermally activated paper sludge, fly ash, and Portland cement was evaluated in…”
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18
Online oxygen monitoring using integrated inkjet-printed sensors in a liver-on-a-chip system
Published in Lab on a chip (01-01-2018)“…The demand for real-time monitoring of cell functions and cell conditions has dramatically increased with the emergence of organ-on-a-chip (OOC) systems…”
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19
EGFR Mutation-Induced Alternative Splicing of Max Contributes to Growth of Glycolytic Tumors in Brain Cancer
Published in Cell metabolism (04-06-2013)“…Alternative splicing contributes to diverse aspects of cancer pathogenesis including altered cellular metabolism, but the specificity of the process or its…”
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20
Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance
Published in Proceedings of the National Academy of Sciences - PNAS (28-07-2015)“…Cancer cells adapt their signaling in response to nutrient availability. To uncover the mechanisms regulating this process and its functional consequences, we…”
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