Search Results - "VILCEK, J"

Interferon research BC (before cloning) by Vilcek, J

“…As we approach the 50th anniversary of the publications describing the discovery of interferon, it is appropriate to look back at some of the trials and…”
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IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice by Aderka, D, Le, JM, Vilcek, J

“…Incubation of the human U937 histiocytic lymphoma cell line with granulocyte-macrophage colony stimulating factor (GM-CSF) rendered the cells responsive to…”
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TSG-14 transgenic mice have improved survival to endotoxemia and to CLP-induced sepsis by Dias, Adriana A. M., Goodman, Adam R., Dos Santos, Jane Lima, Gomes, Rachel Novaes, Altmeyer, Anne, Bozza, Patrícia T., de Fátima Horta, Maria, Vilcek, Jan, Reis, Luiz F. L.

“…Tumor necrosis factor‐stimulated gene 14 (TSG‐14)/PTX3 was identifiedoriginally as a TNF‐α and IL‐1β‐stimulated gene from normal, humanforeskin fibroblasts and…”
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TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-alpha-inhibitor and exerts a strong anti-inflammatory effect in vivo by Wisniewski, HG, Hua, JC, Poppers, DM, Naime, D, Vilcek, J, Cronstein, BN

“…TNF-stimulated gene 6 (tsg6), encoding a 35-kDa secretory glycoprotein (TSG-6), is induced in fibroblasts, chondrocytes, synovial cells, and mononuclear cells…”
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Differential regulation of TSG-14 expression in murine fibroblasts and peritoneal macrophages by Goodman, Adam R., Levy, David E., Reis, Luiz F. L., Vilçek, Jan

“…Tumor necrosis factor (TNF)‐stimulated gene 14 (TSG‐14, also termed PTX3) encodes a secreted glycoprotein whose carboxyterminal half shares sequence similarity…”
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Critical role of a common transcription factor, IRF‐1, in the regulation of IFN‐beta and IFN‐inducible genes by Reis, L.F., Harada, H., Wolchok, J.D., Taniguchi, T., Vilcek, J.

“…Interferon regulatory factor 1 (IRF‐1) is a protein that binds to cis‐elements within the promoter of interferon (IFN)‐beta and some IFN‐inducible genes. We…”
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Induction of the Transcription Factor IRF-1 and Interferon-β mRNAs by Cytokines and Activators of Second-Messenger Pathways by Fujita, Takashi, Luiz F. L. Reis, Watanabe, Nobumasa, Kimura, Yoko, Taniguchi, Tadatsugu, Vilček, Jan

“…Nuclear protein IRF-1 (interferon regulatory factor 1) was earlier shown to bind to cis-acting regulatory elements present on interferon (IFN)-α /β genes and…”
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TSG-14, a tumor necrosis factor- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteins by Lee, GW, Lee, TH, Vilcek, J

“…TNF-stimulated gene (TSG)-14 was originally identified as a TNF-inducible gene in a differentially screened cDNA library derived from TNF-treated normal human…”
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Interleukin 6: a multifunctional cytokine regulating immune reactions and the acute phase protein response by Le, J M, Vilcek, J

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Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities by Le, J, Vilcek, J

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A Novel Secretory Tumor Necrosis Factor-Inducible Protein (TSG-6) Is a Member of the Family of Hyaluronate Binding Proteins, Closely Related to the Adhesion Receptor CD44 by Lee, Tae H., Wisniewski, Hans-Georg, Vilček, Jan

“…TSG-6 cDNA was isolated by differential screening of a λ cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts. We show…”
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Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts by Vietor, I., Schwenger, P., Li, W., Schlessinger, J., Vilcek, J.

“…Tumor necrosis factor (TNF) is a pleiotropic cytokine whose many demonstrated actions include effects on cell growth and differentiation. TNF treatment of…”
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Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP by Zhang, Y, Lin, J X, Vilcek, J

“…Interleukin 6 (IL-6; also referred to as interferon-beta 2, 26-kDa protein, and B cell stimulatory factor 2) is a cytokine whose actions include a stimulation…”
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Enhancement of cAMP Levels and of Protein Kinase Activity by Tumor Necrosis Factor and Interleukin 1 in Human Fibroblasts: Role in the Induction of Interleukin 6 by Zhang, Yihong, Lin, Jian-Xin, Yip, Yum Keung, Vilček, Jan

“…Although tumor necrosis factor (TNF) and interleukin 1 (IL-1) affect many cell functions, the molecular mechanisms of TNF and IL-1 action are not understood…”
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Tumor Necrosis Factor: Specific Binding and Internalization in Sensitive and Resistant Cells by Tsujimoto, M., Yip, Y. K., Vilcek, J.

“…Highly purified, Escherichia coli-derived recombinant human tumor necrosis factor (TNF) was labeled with125I and employed to determine receptor binding,…”
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Soil Environmental Index For Slovak Agricultural Land by Vilcek, J, BUJNOVSKY, R

“…The soil environmental index （SEI）, which is a four digit code system, represents relatively homogenous spatial unit with specific soil capacity to provide…”
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Interferon-gamma enhances expression of cellular receptors for tumor necrosis factor by Tsujimoto, M, Yip, YK, Vilcek, J

“…Incubation of several human tumor cell lines with human interferon-gamma (IFN-gamma) increased the specific binding of subsequently added 125I-labeled…”
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Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence by Zhang, Y H, Lin, J X, Vilcek, J

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Mitogenic and cytotoxic actions of tumor necrosis factor in BALB/c 3T3 cells. Role of phospholipase activation by Palombella, V J, Vilcek, J

“…In addition to its cytotoxic/cytostatic action on many tumor cells in vitro, tumor necrosis factor (TNF) was recently shown to stimulate the growth of some…”
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Transcriptional inhibition of the interleukin-8 gene by interferon is mediated by the NF-kappa B site by Oliveira, I C, Mukaida, N, Matsushima, K, Vilcek, J

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