Search Results - "VILARO, Senén"
-
1
Human adipose tissue as a source of Flk-1+ cells: new method of differentiation and expansion
Published in Cardiovascular research (01-02-2005)“…The low number of postnatal endothelial progenitor cells (EPC) in the circulation limits their therapeutic application in cardiovascular medicine. Processed…”
Get full text
Journal Article -
2
Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition
Published in Journal of cell science (01-11-2006)“…Podoplanin is a small membrane mucin expressed in tumors associated with malignant progression. It is enriched at cell-surface protrusions where it colocalizes…”
Get full text
Journal Article -
3
Syndecan-2 downregulation impairs angiogenesis in human microvascular endothelial cells
Published in Experimental cell research (10-03-2009)“…The formation of new blood vessels, or angiogenesis, is a necessary process during development but also for tumour growth and other pathologies. It is promoted…”
Get full text
Journal Article -
4
The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells
Published in Biochemical journal (01-03-2006)“…Claudin-1 is an integral membrane protein component of tight junctions. The Snail family of transcription factors are repressors that play a central role in…”
Get full text
Journal Article -
5
Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy: Intermediate Filament Protein Expression in Retinal Pigment Epithelial Cells
Published in Investigative ophthalmology & visual science (01-08-1999)“…To improve our understanding of how retinal pigment epithelial (RPE) cells behave in vivo and to establish similarities with dedifferentiation and adaptive…”
Get full text
Journal Article -
6
PDGF-stimulated cell proliferation and migration of human arterial smooth muscle cells. Colocalization of PDGF isoforms with glycosaminoglycans
Published in The international journal of biochemistry & cell biology (2007)“…Platelet-derived growth factor (PDGF) has been implicated in vascular smooth muscle cell proliferation and migration, a key process in vascular disease. PDGF…”
Get full text
Journal Article -
7
Identification of a novel Ezrin-binding site in syndecan-2 cytoplasmic domain
Published in FEBS letters (17-07-2003)“…ERM (Ezrin/Radixin/Moesin) proteins are crosslinkers between plasma membrane proteins and the actin cytoskeleton, thereby involved in the formation of cell…”
Get full text
Journal Article -
8
Comparative study of tube assembly in three-dimensional collagen matrix and on Matrigel coats
Published in Angiogenesis (London) (2002)“…This study compares phenotypic changes of human umbilical endothelial vein cells cultured in three-dimensional collagen matrixes in the presence of basic…”
Get full text
Journal Article -
9
Use of Western blotting filtration to detect UV-cross-linked protein: RNA complexes
Published in Analytical biochemistry (01-06-2006)Get full text
Journal Article -
10
Circulating Endothelial Progenitor Cells After Kidney Transplantation
Published in American journal of transplantation (01-09-2005)“…Circulating endothelial progenitor cells (EPCs) promote vascular repair and maintain integrity of the endothelial monolayer. Reduced EPCs number has been…”
Get full text
Journal Article -
11
Syndecan-2 expression increases serum-withdrawal-induced apoptosis, mediated by re-distribution of Fas into lipid rafts, in stably transfected Swiss 3T3 cells
Published in Apoptosis (London) (01-11-2006)“…To examine the function of syndecan-2, one of the most abundant heparan sulfate proteoglycans in fibroblasts, we obtained stably transfected Swiss 3T3 clones…”
Get full text
Journal Article -
12
Anti-migratory and anti-angiogenic effect of p16 : A novel localization at membrane ruffles and lamellipodia in endothelial cells
Published in Angiogenesis (London) (01-12-2004)“…Recent evidence has established different functions for the tumor suppressor protein, p16(INK4A) aside from controlling the cell cycle. Here we report that…”
Get full text
Journal Article -
13
Effects of heparin on the uptake of lipoprotein lipase in rat liver
Published in BMC physiology (15-11-2004)“…Lipoprotein lipase (LPL) is anchored at the vascular endothelium through interaction with heparan sulfate. It is not known how this enzyme is turned over but…”
Get full text
Journal Article -
14
Evolutionary combinatorial chemistry, a novel tool for SAR studies on peptide transport across the blood-brain barrier. Part 2. Design, synthesis and evaluation of a first generation of peptides
Published in Journal of peptide science (01-12-2005)“…The use of high‐throughput methods in drug discovery allows the generation and testing of a large number of compounds, but at the price of providing redundant…”
Get full text
Journal Article -
15
Fibronectin regulates morphology, cell organization and gene expression of rat fetal hepatocytes in primary culture
Published in Journal of hepatology (01-02-2000)“…Background/Aims: The extracellular matrix regulates hepatic development and regeneration, modulating the maintenance of liver architecture in the…”
Get full text
Journal Article -
16
Lipoprotein lipase-dependent binding and uptake of low density lipoproteins by THP-1 monocytes and macrophages: possible involvement of lipid rafts
Published in Biochimica et biophysica acta (08-11-2004)“…Lipoprotein lipase (LPL) is produced by cells in the artery wall and can mediate binding of lipoproteins to cell surface heparan sulfate proteoglycans (HSPG),…”
Get full text
Journal Article -
17
Effects of growth and differentiation factors on the epithelial-mesenchymal transition in cultured neonatal rat hepatocytes
Published in Journal of hepatology (01-11-1999)“…Background/Aims: Loss of specific differentiation markers, adoption of a migrating morphology and progressive replacement of the cytokeratin network by…”
Get full text
Journal Article -
18
Vimentin Filaments Follow the Preexisting Cytokeratin Network during Epithelial–Mesenchymal Transition of Cultured Neonatal Rat Hepatocytes
Published in Experimental cell research (01-02-1996)“…Changes in cell cytoskeleton are known to play an important role in differentiation and embryogenesis and also in carcinogenesis. Previous studies indicated…”
Get full text
Journal Article -
19
RGD Peptides and Monoclonal Antibodies, Antagonists of αv-Integrin, Enter the Cells by Independent Endocytic Pathways
Published in Laboratory investigation (01-12-2001)“…Cyclic synthetic peptides containing the arginine-glycine-aspartate motif (cRGD) and monoclonal antibodies (mAbs) targeted for individual integrins have been…”
Get full text
Journal Article -
20
Binding and intracellular trafficking of lipoprotein lipase and triacylglycerol-rich lipoproteins by liver cells
Published in Journal of lipid research (01-04-1998)“…The cellular mechanisms and pathways by which lipoprotein lipase (LPL) enhances the binding and uptake of lipoproteins remains unknown. Confocal and…”
Get full text
Journal Article