Search Results - "VILA, M. R"

Defects of intergenomic communication: autosomal disorders that cause multiple deletions and depletion of mitochondrial DNA by Hirano, Michio, Marti, Ramon, Ferreiro-Barros, Claudia, Vilà, Maya R, Tadesse, Saba, Nishigaki, Yutaka, Nishino, Ichizo, Vu, Tuan H

“…Depletion and multiple deletions of mitochondrial DNA (mtDNA) have been associated with a growing number of autosomal diseases that have been classified as…”
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Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein by MÜELLER-PILLASCH, F, LACHER, U, VILA, M. R, ADLER, G, GRESS, T. M, WALLRAPP, C, MICHA, A, ZIMMERHACKL, F, HAMEISTER, H, VARGA, G, FRIESS, H, BÜCHLER, M, BEGERS, H. G

“…In a previous large scale screen for differentially expressed genes in pancreatic cancer, we identified a gene highly overexpressed in cancer encoding a novel…”
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Normal human pancreas cultures display functional ductal characteristics by Vila, M R, Lloreta, J, Real, F X

“…Normal cell cultures are invaluable in the analysis of cell differentiation and neoplastic transformation. We have developed methods to reproducibly culture…”
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Increased glyceraldehyde‐3‐phosphate dehydrogenase expression in renal cell carcinoma identified by RNA‐based, arbitrarily primed polymerase chain reaction by Vilà, Maya R., Nicolás, Antoni, Morote, Joan, de Torres, Inés, Meseguer, Anna

“…BACKGROUND Renal cell carcinoma (RCC) comprises 85% of renal tumors and displays a great capacity to metastasize. The lack of diagnostic and prognostic markers…”
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The effect of non-ionic surfactant vesicle (niosome) entrapment on the absorption and distribution of methotrexate in mice by Azmin, M N, Florence, A T, Handjani-Vila, R M, Stuart, J F, Vanlerberghe, G, Whittaker, J S

“…Non-ionic surfactant vesicles (niosomes) prepared from a non-ionic surfactant, cholesterol and dicetyl phosphate and containing methotrexate (MTX) have been…”
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Molecular insight into mitochondrial DNA depletion syndrome in two patients with novel mutations in the deoxyguanosine kinase and thymidine kinase 2 genes by Wang, Liya, Limongelli, Anna, Vila, Maya R., Carrara, Franco, Zeviani, Massimo, Eriksson, Staffan

“…Thymidine kinase 2 (TK2) and deoxyguanosine kinase (dGK) are the two key enzymes in mitochondrial DNA (mtDNA) precursor synthesis. Deficiencies in TK2 or dGK…”
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Reversion of mtDNA depletion in a patient with TK2 deficiency by VILA, M. R, SEGOVIA-SILVESTRE, T, ANDREU, A. L, GAMEZ, J, MARINA, A, NAINI, A. B, MESEGUER, A, LOMBES, A, BONILLA, E, DIMAURO, S, HIRANO, M

“…Mutations in the thymidine kinase 2 (TK2) gene cause a myopathic form of the mitochondrial DNA depletion syndrome (MDS). Here, the authors report the unusual…”
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JAK2 V617F mutation analysis in different myeloid lineages (granulocytes, platelets, CFU-MK, BFU-E and CFU-GM) in essential thrombocythemia patients by Florensa, L, Bellosillo, B, Besses, C, Puigdecanet, E, Espinet, B, Pérez-Vila, E, Longarón, R, Vilà, R M, Solé, F, Serrano, S

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The use of ITS1 rDNA PCR in detecting pathogenic African trypanosomes by NJIRU, Z. K, CONSTANTINE, C. C, GUYA, S, CROWTHER, J, KIRAGU, J. M, THOMPSON, R. C. A, DAVILA, A. M. R

“…There are 11 different pathogenic trypanosomes in trypanosomiasis endemic regions of Africa. Their detection and characterisation by molecular methods relies…”
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A novel autosomal dominant limb-girdle muscular dystrophy (LGMD 1F) maps to 7q32.1-32.2 by Palenzuela, L, Andreu, A L, Gàmez, J, Vilà, M R, Kunimatsu, T, Meseguer, A, Cervera, C, Fernandez Cadenas, I, van der Ven, P F M, Nygaard, T G, Bonilla, E, Hirano, M

“…In 2001, the authors described the clinical features of a genetically distinct autosomal dominant limb-girdle muscular dystrophy (LGMD; LGMD 1F). Using a…”
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Immunocytochemical investigation of normal and chronic lymphocytic leukaemia lymphocytes reveals unexpectedly frequent reactivity with some myelomonocytic associated antibodies by Woessner, S, Florensa, L, Besses, C, Vilà, R M, Gallés, C, Palou, L, Sabrafen, J S

“…Information about the expression of some myelomonocytic markers in lymphocytes of patients with B-CLL is scarce. We studied the CD13, CD14, CD11c and CD68…”
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Role of UEV-1, an inactive variant of the E2 ubiquitin-conjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29-M6 intestinal mucosecretory cells by Sancho, E, Vilá, M R, Sánchez-Pulido, L, Lozano, J J, Paciucci, R, Nadal, M, Fox, M, Harvey, C, Bercovich, B, Loukili, N, Ciechanover, A, Lin, S L, Sanz, F, Estivill, X, Valencia, A, Thomson, T M

“…By means of differential RNA display, we have isolated a cDNA corresponding to transcripts that are down-regulated upon differentiation of the goblet cell-like…”
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Hepatocyte growth factor is a potent mitogen for normal human pancreas cells in vitro by Vilá, M R, Nakamura, T, Real, F X

“…Little is known regarding the mechanisms that regulate cell proliferation in the exocrine pancreas. The aim of this study was to analyze the effect of growth…”
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Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System and Redistribution of E-Cadherin Are Associated with Hepatocyte Growth Factor-Induced Motility of Pancreas Tumor Cells Overexpressing Met by Paciucci, Rosanna, Vilá, Maya R., Adell, Teresa, Díaz, Víctor M., Torà, Montserrat, Nakamura, Toshikazu, Real, Francisco X.

“…Because hepatocyte growth factor (HGF) is a potent mitogen for normal human exocrine pancreas cells (NPCs) in vitro, we have analyzed the expression of HGF and…”
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Uncoupling Protein-1 mRNA Expression in Lipomas from Patients Bearing Pathogenic Mitochondrial DNA Mutations by Vilà, Maya R., Gámez, Josep, Solano, Abelardo, Playán, Ana, Schwartz, Simó, Santorelli, Filippo M., Cervera, Carles, Casali, Carlo, Montoya, Julio, Villarroya, Francesc

“…Multiple symmetric lipomatosis (MSL) is a rare disorder characterised by large subcutaneous fat masses in some parts of the trunk. Mitochondrial disfunction is…”
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The effect of niosomes and polysorbate 80 on the metabolism and excretion of methotrexate in the mouse by Azmin, M N, Florence, A T, Handjani-Vila, R M, Stuart, J F, Vanlerberghe, G, Whittaker, J S

“…The effect of non-ionic surfactant vesicle (niosome) encapsulation on the metabolism and urinary and faecal excretion of methotrexate (MTX) in mice has been…”
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Trisomy 12 is a rare cytogenetic finding in typical chronic lymphocytic leukemia by Woessner, S., Solé, F., Pérez-Losada, A., Florensa, L., Vilá, R.M.

“…We have studied 61 cases of B-chronic lymphocytic leukemia (CLL), combining cytological features, conventional cytogenetics and in situ hybridization (ISH)…”
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Glycosyl phosphatidylinositol membrane anchoring of melanotransferrin (p97) : apical compartmentalization in intestinal epithelial cells by ALEMANY, R, VILA, M. R, FRANCI, C, EGEA, G, REAL, F. X, THOMSON, T. M

“…Melanotransferrin (p97) is an iron-binding membrane glycoprotein with 40% homology to transferrin and lactoferrin. It was first identified on the basis of its…”
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Anatomical study of the ulnar nerve in the hand by Bonnel, F, Vila, R M

“…This anatomical study is based on the dissection of fifty adult hands. The classic configuration of the ulnar nerve was found in thirty-nine cases out of…”
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An in vitro tool to assess cytochrome P450 drug biotransformation-dependent cytotoxicity in engineered HepG2 cells generated by using adenoviral vectors by Lahoz, Agustín, Vilà, Maya R., Fabre, Myriam, Miquel, Josep M., Rivas, Manuel, Maines, Jessica, Castell, José V., Gómez-Lechón, M. José

“…► We have developed an in vitro tool to detect bioactivation-dependent toxicity. ► We can identify CYP enzymes involved in metabolism-based toxicity. ► We are…”
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