Search Results - "VIEGAS, T. X"

Pharmacokinetics and Pharmacodynamics of Peldesine (BCX-34), a Purine Nucleoside Phosphorylase Inhibitor, following Single and Multiple Oral Doses in Healthy Volunteers by Viegas, Tacey X., Omura, George A., Stoltz, Randall R., Kisicki, James

“…The pharmacokinetic parameters of peldesine (BCX‐34) were investigated after single and multiple oral doses in two groups of healthy adult volunteers. The…”
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Relative bioavailability of danazol in dogs from liquid-filled hard gelatin capsules by Erlich, LuAnn, Yu, Danny, Pallister, David A., Levinson, R.Saul, Gole, Dilip G., Wilkinson, Paul A., Erlich, Ronald E., Reeve, Lorraine E., Viegas, Tacey X.

“…Danazol was dissolved in non-aqueous mixtures containing either polyethylene glycol 400 or polysorbate 80, and filled into hard gelatin capsules at 50 mg…”
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Evaluation of creams and ointments as suitable formulations for peldesine by Viegas, Tacey X, Van Winkle, Lise L, Lehman, Paul A, Franz, Sue F, Franz, Thomas J

“…In-vitro studies were conducted to study the efficacy of mixed and self-emulsifying creams and hydrophobic ointment formulations in delivering peldesine…”
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Osmotic behavior of poloxamer 407 and other non-ionic surfactants in aqueous solutions by Viegas, Tacey X, Henry, Raymond L

“…Solutions of non-ionic surfactants were prepared in water and buffer. The osmotic behavior of these solutions were studied by measuring their osmolality, using…”
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Percutaneous absorption of bendroflumethiazide from gel and membrane-controlled gel systems: an in vitro and in vivo study by Viegas, Tacey X, Hikal, Ahmed H, Jones, Alan B

“…A number of gel formulations were developed for bendroflumethiazide (BFTZ). The gels were composed of BFTZ dissolved in an alcohol–polyol–water medium and…”
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Preformulation studies for the development of a parenteral liquid formulation of the immunomodulator, peldesine by Viegas, T X, Van Winkle, L L

“…Peldesine (BCX-34) is a potent inhibitor of the enzyme purine nucleoside phosphorylase (PNP). The object of this study was to determine the preformulation…”
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An in vitro method of evaluating tolnaftate release from topical powder by VIEGAS, T. X, KIBBE, A. H, HIKAL, A. H, CLEARY, R. W, JONES, A. B

“…A dissolution apparatus was constructed to evaluate tolnaftate release from topical powders. It consisted of a mesh unit to support the powder, a receptor…”
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