Search Results - "VICTORINO, Francisco"

HIF1α is required for NK cell metabolic adaptation during virus infection by Victorino, Francisco, Bigley, Tarin M, Park, Eugene, Yao, Cong-Hui, Benoit, Jeanne, Yang, Li-Ping, Piersma, Sytse J, Lauron, Elvin J, Davidson, Rebecca M, Patti, Gary J, Yokoyama, Wayne M

“…Natural killer (NK) cells are essential for early protection against virus infection and must metabolically adapt to the energy demands of activation. Here, we…”
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Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes by SARKAR, Suparna A, LEE, Catherine E, VICTORINO, Francisco, NGUYEN, Tom T, WALTERS, Jay A, BURRACK, Adam, EBERLEIN, Jens, HILDEMANN, Steven K, HOMANN, Dirk

“…More than one-half of the ~50 human chemokines have been associated with or implicated in the pathogenesis of type 1 diabetes, yet their actual expression…”
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NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury by Hoegl, Sandra, Ehrentraut, Heidi, Brodsky, Kelley S., Victorino, Francisco, Golden‐Mason, Lucy, Eltzschig, Holger K., McNamee, Eóin N.

“…A critical step in the pathogenesis of acute lung injury (ALI) is excessive recruitment of polymorphonuclear neutrophils (PMNs) into the lungs, causing…”
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Aging boosts antiviral CD8+T cell memory through improved engagement of diversified recall response determinants by Davenport, Bennett, Eberlein, Jens, Nguyen, Tom T, Victorino, Francisco, Jhun, Kevin, Abuirqeba, Haedar, van der Heide, Verena, Heeger, Peter, Homann, Dirk

“…The determinants of protective CD8+ memory T cell (CD8+TM) immunity remain incompletely defined and may in fact constitute an evolving agency as aging CD8+TM…”
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High efficiency of antiviral CD4(+) killer T cells by Hildemann, Steven K, Eberlein, Jens, Davenport, Bennett, Nguyen, Tom T, Victorino, Francisco, Homann, Dirk

“…The destruction of infected cells by cytotxic T lymphocytes (CTL) is integral to the effective control of viral and bacterial diseases, and CTL function at…”
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Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response by Hu, Jiancheng, Oda, Shannon K, Shotts, Kristin, Donovan, Erin E, Strauch, Pamela, Pujanauski, Lindsey M, Victorino, Francisco, Al-Shami, Amin, Fujiwara, Yuko, Tigyi, Gabor, Oravecz, Tamas, Pelanda, Roberta, Torres, Raul M

“…Lysophospholipids have emerged as biologically important chemoattractants capable of directing lymphocyte development, trafficking, and localization…”
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Multiple Layers of CD80/86-Dependent Costimulatory Activity Regulate Primary, Memory, and Secondary Lymphocytic Choriomeningitis Virus-Specific T Cell Immunity by EBERLEIN, Jens, DAVENPORT, Bennett, NGUYEN, Tom T, VICTORINO, Francisco, SPARWASSER, Tim, HOMANN, Dirk

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Low‐Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells by House, John S., Bouzos, Evangelia, Fahy, Kira M., Francisco, Victorino Miguel, Lloyd, Dillon T., Wright, Fred A., Motsinger‐Reif, Alison A., Asuri, Prashanth, Wheeler, Korin E.

“…Silver nanoparticles (AgNPs) are widely incorporated into consumer and biomedical products for their antimicrobial and plasmonic properties with limited risk…”
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Isotype-Specific Autoantibody Signatures in Cancer and Sepsis Samples through Multiplex Profiling by Gilliam, Brooke, Pfeifer, Justin, McDonald, John, Victorino, Francisco, Qiang, Xiao, Hoberg, James, Lie, Wen-Rong

“…Many diseases can be characterized by specific autoantibodies. The Luminex™ multi-analyte profiling platform enables simultaneous detection a panel of…”
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222: NEONATAL MURINE ROSEOLOVIRUS INFECTION DISRUPTS IMMUNE TOLERANCE AND INDUCES AUTOIMMUNE GASTRITIS by Bigley, Tarin M., Yang, Liping, Kang, Liang-I, Saenz, Jose, Victorino, Francisco, Yokoyama, Wayne

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Chemokine Signatures of Pathogen-Specific T Cells I: Effector T Cells by Eberlein, Jens, Davenport, Bennett, Nguyen, Tom T, Victorino, Francisco, Jhun, Kevin, van der Heide, Verena, Kuleshov, Maxim, Ma'ayan, Avi, Kedl, Ross, Homann, Dirk

“…The choreography of complex immune responses, including the priming, differentiation, and modulation of specific effector T cell populations generated in the…”
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Disruption of thymic central tolerance by infection with murine roseolovirus induces autoimmune gastritis by Bigley, Tarin M, Yang, Liping, Kang, Liang-I, Saenz, Jose B, Victorino, Francisco, Yokoyama, Wayne M

“…Infections with herpesviruses, including human roseoloviruses, have been proposed to cause autoimmune disease, but defining a causal relationship and mechanism…”
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Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody by Victorino, Francisco, Sojka, Dorothy K, Brodsky, Kelley S, McNamee, Eoin N, Masterson, Joanne C, Homann, Dirk, Yokoyama, Wayne M, Eltzschig, Holger K, Clambey, Eric T

“…NK cells are innate lymphoid cells important for immune surveillance, identifying and responding to stress, infection, and/or transformation. Whereas…”
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Chemokine Signatures of Pathogen-Specific T Cells II: Memory T Cells in Acute and Chronic Infection by Davenport, Bennett, Eberlein, Jens, Nguyen, Tom T, Victorino, Francisco, van der Heide, Verena, Kuleshov, Maxim, Ma'ayan, Avi, Kedl, Ross, Homann, Dirk

“…Pathogen-specific memory T cells (T ) contribute to enhanced immune protection under conditions of reinfection, and their effective recruitment into a recall…”
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Identifying novel spatiotemporal regulators of innate immunity by Victorino, Francisco, Alper, Scott

“…The innate immune response plays a critical role in pathogen clearance. However, dysregulation of innate immunity contributes to acute inflammatory diseases…”
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Hypoxia inducible factor-1a drives metabolic adaptation of natural killer cells during pathogen infection by Victorino, Francisco, Bigley, Tarin, Park, Eugene, Yao, Conghui, Benoit, Jeanne, Yang, Li-Ping, Plougastel-Douglas, Beatrice, Piersma, Sytse, Lauron, Elvin, Davidson, Rebecca, Patti, Gary, Yokoyama, Wayne

“…Natural killer (NK) cells provide an early response to pathogen infection, limiting host morbidity and lethality. This response requires NK cells to adapt due…”
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Aging of Antiviral CD8 + Memory T Cells Fosters Increased Survival, Metabolic Adaptations, and Lymphoid Tissue Homing by Davenport, Bennett, Eberlein, Jens, van der Heide, Verena, Jhun, Kevin, Nguyen, Tom T, Victorino, Francisco, Trotta, Andrew, Chipuk, Jerry, Yi, Zhengzi, Zhang, Weijia, Clambey, Eric T, Scott, Donald K, Homann, Dirk

“…Aging of established antiviral T cell memory can foster a series of progressive adaptations that paradoxically improve rather than compromise protective CD8 T…”
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Aging promotes acquisition of naive-like CD8+ memory T cell traits and enhanced functionalities by Eberlein, Jens, Davenport, Bennett, Nguyen, Tom, Victorino, Francisco, Haist, Kelsey, Jhun, Kevin, Karimpour-Fard, Anis, Hunter, Lawrence, Kedl, Ross, Clambey, Eric T, Homann, Dirk

“…Protective T cell memory is an acquired trait that is contingent upon the preservation of its constituents and therefore vulnerable to the potentially…”
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Viral MHCI inhibition evades tissue-resident memory T cell formation and responses by Lauron, Elvin J, Yang, Liping, Harvey, Ian B, Sojka, Dorothy K, Williams, Graham D, Paley, Michael A, Bern, Michael D, Park, Eugene, Victorino, Francisco, Boon, Adrianus C M, Yokoyama, Wayne M

“…Tissue-resident memory CD8 T cells (T s) confer rapid protection and immunity against viral infections. Many viruses have evolved mechanisms to inhibit MHCI…”
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Comprehensive assessment of chemokine expression profiles by flow cytometry by Eberlein, Jens, Nguyen, Tom T, Victorino, Francisco, Golden-Mason, Lucy, Rosen, Hugo R, Homann, Dirk

“…The chemokines are a large family of mainly secreted molecules involved in the regulation of numerous physiological and pathophysiological processes. Despite…”
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