Search Results - "VERWEIJ, W"
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Preparation of Colloidal Organosilica Spheres through Spontaneous Emulsification
Published in Langmuir (22-08-2017)“…Colloidal particles of controlled size are promising building blocks for the self-assembly of functional materials. Here, we systematically study a method to…”
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Homogeneous, Real-Time NanoBRET Binding Assays for the Histamine H 3 and H 4 Receptors on Living Cells
Published in Molecular pharmacology (01-12-2018)“…Receptor-binding affinity and ligand-receptor residence time are key parameters for the selection of drug candidates and are routinely determined using…”
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3
Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology
Published in Journal of the American Chemical Society (28-03-2018)“…Noninvasive methods to modulate G protein-coupled receptors (GPCRs) with temporal and spatial precision are in great demand. Photopharmacology uses photons to…”
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BRET-Based Biosensors to Measure Agonist Efficacies in Histamine H1 Receptor-Mediated G Protein Activation, Signaling and Interactions with GRKs and β-Arrestins
Published in International journal of molecular sciences (16-03-2022)“…The histamine H1 receptor (H1R) is a G protein-coupled receptor (GPCR) and plays a key role in allergic reactions upon activation by histamine which is locally…”
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Identification of TSPAN4 as Novel Histamine H4 Receptor Interactor
Published in Biomolecules (Basel, Switzerland) (30-07-2021)“…The histamine H4 receptor (H4R) is a G protein-coupled receptor that is predominantly expressed on immune cells and considered to be an important drug target…”
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Bacterial Colonization of the Lower Airways in Children With Esophageal Atresia
Published in The Pediatric infectious disease journal (01-08-2023)“…Esophageal atresia (EA) is most often accompanied by some degree of tracheomalacia (TM), which negatively influences the airway by ineffective clearance of…”
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Distribution of the glucocorticoid receptor in the human amygdala; changes in mood disorder patients
Published in Brain Structure and Function (01-09-2014)“…Exposure to stress activates the hypothalamic–pituitary–adrenal (HPA) axis that stimulates glucocorticoid (GC) release from the adrenal. These hormones exert…”
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HPV DNA testing in population-based cervical screening (VUSA-Screen study): results and implications
Published in British journal of cancer (28-02-2012)“…Background: Human papillomavirus (HPV) testing is more sensitive than cytology for detecting high-grade cervical intraepithelial neoplasia (CIN). We evaluated…”
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Ektacytometry Analysis of Post-splenectomy Red Blood Cell Properties Identifies Cell Membrane Stability Test as a Novel Biomarker of Membrane Health in Hereditary Spherocytosis
Published in Frontiers in physiology (25-03-2021)“…Hereditary spherocytosis (HS) is the most common form of hereditary chronic hemolytic anemia. It is caused by mutations in red blood cell (RBC) membrane and…”
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Differential Role of Serines and Threonines in Intracellular Loop 3 and C-Terminal Tail of the Histamine H 4 Receptor in β-Arrestin and G Protein-Coupled Receptor Kinase Interaction, Internalization, and Signaling
Published in ACS pharmacology & translational science (10-04-2020)“…The histamine H receptor (H R) activates Gα -mediated signaling and recruits β-arrestin2 upon stimulation with histamine. β-Arrestins play a regulatory role in…”
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Primary Posterior Tracheopexy in Esophageal Atresia Decreases Respiratory Tract Infections
Published in Frontiers in pediatrics (09-09-2021)“…Background: Esophageal atresia (EA) is often accompanied by tracheomalacia (TM). TM can lead to severe respiratory complaints requiring invasive treatment…”
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Differential Role of Serines and Threonines in Intracellular Loop 3 and C‑Terminal Tail of the Histamine H4 Receptor in β‑Arrestin and G Protein-Coupled Receptor Kinase Interaction, Internalization, and Signaling
Published in ACS pharmacology & translational science (10-04-2020)“…The histamine H4 receptor (H4R) activates Gαi-mediated signaling and recruits β-arrestin2 upon stimulation with histamine. β-Arrestins play a regulatory role…”
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Airway Epithelial Cultures of Children with Esophageal Atresia as a Model to Study Respiratory Tract Disorders
Published in Children (Basel) (01-06-2023)“…Esophageal atresia (EA) is a rare birth defect in which respiratory tract disorders are a major cause of morbidity. It remains unclear whether respiratory…”
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Adenoviruses from Human Immunodeficiency Virus-Infected Individuals, Including Two Strains That Represent New Candidate Serotypes Ad50 and Ad51 of Species B1 and D, Respectively
Published in Journal of Clinical Microbiology (01-12-1999)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Dumbbell Impurities in 2D Crystals of Repulsive Colloidal Spheres Trap Dislocations
Published in Physical review letters (11-10-2024)“…Impurity-induced defects play a crucial role for the properties of crystals, but little is known about impurities with anisotropic shape. Here, we study how…”
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The association between intelligence scores and family history of psychiatric disorder in schizophrenia patients, their siblings and healthy controls
Published in PloS one (09-10-2013)“…The degree of intellectual impairment in schizophrenia patients and their relatives has been suggested to be associated with the degree of familial loading for…”
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Self-Assembly Dynamics of Reconfigurable Colloidal Molecules
Published in ACS nano (22-02-2022)“…Colloidal molecules are designed to mimic their molecular analogues through their anisotropic shape and interactions. However, current experimental…”
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Flexible Colloidal Molecules with Directional Bonds and Controlled Flexibility
Published in ACS nano (11-07-2023)“…Colloidal molecules are ideal model systems for mimicking real molecules and can serve as versatile building blocks for the bottom-up self-assembly of flexible…”
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Colloidal Recycling: Reconfiguration of Random Aggregates into Patchy Particles
Published in ACS nano (26-04-2016)“…The key ingredients to the successful bottom-up construction of complex materials are believed to be colloids with anisotropic shapes and directional, or…”
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Flexibility-induced effects in the Brownian motion of colloidal trimers
Published in Physical review research (24-07-2020)“…Shape changes resulting from segmental flexibility are ubiquitous in molecular and biological systems, and are expected to affect both the diffusive motion and…”
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