Search Results - "VERSTAPPEN, Suzanne M. M"

Differential DNA methylation correlates with response to methotrexate in rheumatoid arthritis by Nair, Nisha, Plant, Darren, Verstappen, Suzanne M, Isaacs, John D, Morgan, Ann W, Hyrich, Kimme L, Barton, Anne, Wilson, Anthony G

“…Abstract Objectives Identifying blood-based biomarkers that predict treatment response in RA is a clinical priority. We investigated differential DNA…”
Get full text

Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS) by Sergeant, Jamie C, Hyrich, Kimme L, Anderson, James, Kopec-Harding, Kamilla, Hope, Holly F, Symmons, Deborah P M, Barton, Anne, Verstappen, Suzanne M M

“…Methotrexate (MTX) remains the disease-modifying anti-rheumatic drug of first choice in rheumatoid arthritis (RA) but response varies. Predicting non-response…”
Get full text

Low-Dose Prednisone Inclusion in a Methotrexate-Based, Tight Control Strategy for Early Rheumatoid Arthritis: A Randomized Trial by BAKKER, Marije F, JACOBS, Johannes W. G, VAN DER VEEN, Maaike J, VERHOEF, Catharina M, LAFEBER, Floris P. J. G, BIJLSMA, Johannes W. J, WELSING, Paco M. J, VERSTAPPEN, Suzanne M. M, TEKSTRA, Janneke, TON, Evelien, GEURTS, Monique A. W, VAN DER WERF, Jacobine H, VAN ALBADA-KUIPERS, Grietje A, JAHANGIER-DE VEEN, Zalima N

“…Treatment strategies for tight control of early rheumatoid arthritis (RA) are highly effective but can be improved. To investigate whether adding prednisone,…”
Get full text

Predicting presenteeism using measures of health status by Jones, Cheryl, Payne, Katherine, Thompson, Alexander, Verstappen, Suzanne M. M.

“…Objectives To identify whether it is feasible to develop a mapping algorithm to predict presenteeism using multiattribute measures of health status. Methods…”
Get full text

Using qualitative methods for a conceptual analysis of measures of health status and presenteeism prior to a mapping study by Jones, Cheryl, Payne, Katherine, Verstappen, Suzanne M. M.

“…Objectives The inclusion of productivity in economic evaluations is a contentious issue. Methods are currently being developed to assess how it may feasibly be…”
Get full text

In patients with early rheumatoid arthritis, the new ACR/EULAR definition of remission identifies patients with persistent absence of functional disability and suppression of ultrasonographic synovitis by Sakellariou, Garifallia, Scirè, Carlo Alberto, Verstappen, Suzanne M M, Montecucco, Carlomaurizio, Caporali, Roberto

“…To test the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) and disease activity score in 44 and 28 joints (DAS, DAS28)…”
Get more information

A general framework for selecting work participation outcomes in intervention studies among persons with health problems: a concept paper by Ravinskaya, Margarita, Verbeek, Jos H, Langendam, Miranda W, Madan, Ira, Verstappen, Suzanne M. M, Kunz, Regina, Hulshof, Carel T. J, Hoving, Jan L

“…Abstract Background Work participation is important for health and can be considered as engagement in a major area of life which is of significance for most…”
Get full text

Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register by Verstappen, Suzanne M M, King, Yvonne, Watson, Kath D, Symmons, Deborah P M, Hyrich, Kimme L

“…The British Society for Rheumatology Biologics Register (BSRBR) has collected data on adverse events including pregnancies in patients with rheumatoid…”
Get more information

Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA study by Sokka, Tuulikki, Kautiainen, Hannu, Pincus, Theodore, Verstappen, Suzanne M M, Aggarwal, Amita, Alten, Rieke, Andersone, Daina, Badsha, Humeira, Baecklund, Eva, Belmonte, Miguel, Craig-Müller, Jürgen, da Mota, Licia Maria Henrique, Dimic, Alexander, Fathi, Nihal A, Ferraccioli, Gianfranco, Fukuda, Wataru, Géher, Pál, Gogus, Feride, Hajjaj-Hassouni, Najia, Hamoud, Hisham, Haugeberg, Glenn, Henrohn, Dan, Horslev-Petersen, Kim, Ionescu, Ruxandra, Karateew, Dmitry, Kuuse, Reet, Laurindo, Ieda Maria Magalhaes, Lazovskis, Juris, Luukkainen, Reijo, Mofti, Ayman, Murphy, Eithne, Nakajima, Ayako, Oyoo, Omondi, Pandya, Sapan C, Pohl, Christof, Predeteanu, Denisa, Rexhepi, Mjellma, Rexhepi, Sylejman, Sharma, Banwari, Shono, Eisuke, Sibilia, Jean, Sierakowski, Stanislaw, Skopouli, Fotini N, Stropuviene, Sigita, Toloza, Sergio, Valter, Ivo, Woolf, Anthony, Yamanaka, Hisashi

“…Work disability is a major consequence of rheumatoid arthritis (RA), associated not only with traditional disease activity variables, but also more…”
Get full text

Risk factors for oral methotrexate failure in patients with inflammatory polyarthritis: results from a UK prospective cohort study by Bluett, James, Sergeant, Jamie C, MacGregor, Alex J, Chipping, Jacqueline R, Marshall, Tarnya, Symmons, Deborah P M, Verstappen, Suzanne M M

“…Oral methotrexate (MTX) is the first-line therapy for patients with rheumatoid arthritis (RA). However, approximately one quarter of patients discontinue MTX…”
Get full text

Systematic review of the predictors of statin adherence for the primary prevention of cardiovascular disease by Hope, Holly F, Binkley, George M, Fenton, Sally, Kitas, George D, Verstappen, Suzanne M M, Symmons, Deborah P M

“…Previous research has shown that statin adherence for the primary prevention of CVD is lower compared to secondary prevention populations. Therefore the aim of…”
Get full text

Proteomic analysis to define predictors of treatment response to adalimumab or methotrexate in rheumatoid arthritis patients by Ling, Stephanie F., Nair, Nisha, Verstappen, Suzanne M. M., Barton, Anne, Zucht, Hans-Dieter, Budde, Petra, Schulz-Knappe, Peter, Plant, Darren

“…Seropositivity for anti-citrullinated peptide antibodies (ACPA) in patients with rheumatoid arthritis (RA), a chronic autoimmune arthritis, is associated with…”
Get full text

Preferred Methods of Measuring Work Participation: An International Survey Among Trialists and Cochrane Systematic Reviewers by Ravinskaya, Margarita, Verbeek, Jos H., Langendam, Miranda W., Madan, Ira, Verstappen, Suzanne M. M., Kunz, Regina, Hulshof, Carel T. J., Hoving, Jan L.

“…Purpose Heterogeneity in work participation (WP) outcomes measurements hampers large scale evidence synthesis in systematic reviews of trials. In this survey…”
Get full text

How to develop, validate, and update clinical prediction models using multinomial logistic regression by Gehringer, Celina K., Martin, Glen P., Van Calster, Ben, Hyrich, Kimme L., Verstappen, Suzanne M.M., Sergeant, Jamie C.

“…Multicategory prediction models (MPMs) can be used in health care when the primary outcome of interest has more than two categories. The application of MPMs is…”
Get full text

Conceptual model for the health technology assessment of current and novel interventions in rheumatoid arthritis by Alemao, Evo, Al, Maiwenn J, Boonen, Annelies A, Stevenson, Matthew D, Verstappen, Suzanne M M, Michaud, Kaleb, Weinblatt, Michael E, Rutten-van Mölken, Maureen P M H

“…The objective of this study was to evaluate current approaches to economic modeling in rheumatoid arthritis (RA) and propose a new conceptual model for…”
Get full text

Developing and externally validating multinomial prediction models for methotrexate treatment outcomes in patients with rheumatoid arthritis: results from an international collaboration by Gehringer, Celina K., Martin, Glen P., Hyrich, Kimme L., Verstappen, Suzanne M.M., Sexton, Joseph, Kristianslund, Eirik K., Provan, Sella A., Kvien, Tore K., Sergeant, Jamie C.

“…In rheumatology, there is a clinical need to identify patients at high risk (>50%) of not responding to the first-line therapy methotrexate (MTX) due to lack…”
Get full text

Correction: Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity by Pan, Yi, Norton, Sam, Gwinnutt, James M, Kearsley-Fleet, Lianne, Symmons, Deborah P M, Lunt, Mark, Young, Adam, Hyrich, Kimme L, Verstappen, Suzanne M M

“…[This corrects the article DOI: 10.1371/journal.pone.0215999.]…”
Get full text

Predictors of presenteeism, absenteeism and job loss in patients commencing methotrexate or biologic therapy for rheumatoid arthritis by Gwinnutt, James M, Leggett, Sarah, Lunt, Mark, Barton, Anne, Hyrich, Kimme L, Walker-Bone, Karen, Verstappen, Suzanne M M

“…Abstract Objectives Work is an important health outcome. This study aimed to identify predictors of work loss, absenteeism and presenteeism over 1 year in RA…”
Get full text

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study by van Wesemael, Tineke J, Ajeganova, Sofia, Humphreys, Jennifer, Terao, Chikashi, Muhammad, Ammar, Symmons, Deborah P M, MacGregor, Alex J, Hafström, Ingiäld, Trouw, Leendert A, van der Helm-van Mil, Annette H M, Huizinga, Tom W J, Mimori, Tsuneyo, Toes, René E M, Matsuda, Fumihiko, Svensson, Björn, Verstappen, Suzanne M M, van der Woude, Diane

“…The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA). In…”
Get full text

Has the Severity of Rheumatoid Arthritis at Presentation Diminished Over Time? by DIFFIN, Janet G, LUNT, Mark, MARSHALL, Tarnya, CHIPPING, Jacqueline R, SYMMONS, Deborah P. M, VERSTAPPEN, Suzanne M. M

“…To examine the pattern of disease severity in patients with rheumatoid arthritis (RA) at presentation to the Norfolk Arthritis Register (NOAR) over 20 years…”
Get full text