Search Results - "VENNSTROM, B"

Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area by Harder, L., Dudazy‐Gralla, S., Müller‐Fielitz, H., Hjerling Leffler, J., Vennström, B., Heuer, H., Mittag, J.

“…Thyroid hormone (TH) is crucial for brain development and function. This becomes most evident in untreated congenital hypothyroidism, leading to irreversible…”
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Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation by Göthe, S, Wang, Z, Ng, L, Kindblom, J M, Barros, A C, Ohlsson, C, Vennström, B, Forrest, D

“…Thyroid hormone (T3) has widespread functions in development and homeostasis, although the receptor pathways by which this diversity arises are unclear…”
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Functions of thyroid hormone receptors in mice by Forrest, D, Vennström, B

“…Thyroid hormone receptors (TRs) play a central role in mediating the actions of thyroid hormone in development and homeostasis in vertebrate species. The TRs…”
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A thyroid hormone receptor that is required for the development of green cone photoreceptors by Reh, Thomas A, Forrest, Douglas, Ng, Lily, Hurley, James B, Dierks, Blair, Srinivas, Maya, Saltó, Carmen, Vennström, Björn

“…Color vision is facilitated by distinct populations of cone photoreceptors in the retina. In rodents, cones expressing different opsin photopigments are…”
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Lack of thyroid hormone receptor α1 is associated with selective alterations in behavior and hippocampal circuits by GUADANO-FERRAZ, A, BENAVIDES-PICCIONE, R, VENERO, C, LANCHA, C, VENNSTRÖM, B, SANDI, C, DEFELIPE, J, BERNAL, J

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Depressed Thermogenesis but Competent Brown Adipose Tissue Recruitment in Mice Devoid of All Hormone-Binding Thyroid Hormone Receptors by Golozoubova, Valeria, Gullberg, Hjalmar, Matthias, Anita, Cannon, Barbara, Vennström, Björn, Nedergaard, Jan

“…We have examined the metabolic role of hormone-binding nuclear thyroid hormone receptors (TRs). Mice devoid of all hormone-binding TRs [TRα1(−/−)β(−/−)…”
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Thyroid hormone receptor α can control action potential duration in mouse ventricular myocytes through the KCNE1 ion channel subunit by Mansén, A, Tiselius, C, Sand, P, Fauconnier, J, Westerblad, H, Rydqvist, B, Vennström, B

“…The reduced heart rate and prolonged QTend duration in mice deficient in thyroid hormone receptor (TR) α1 may involve aberrant expression of the K⁺ channel…”
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A unified nomenclature system for the nuclear receptor superfamily by Auwerx, J, Baulieu, E, Beato, M, Becker-Andre, M, Burbach, PH, Camerino, G, Chambon, P, Cooney, A, Dejean, A, Dreyer, C, Evans, RM, Gannon, F, Giguere, V, Gronemeyer, H, Gustafson, JA, Laudet, V, Lazar, MA, Mangelsdorf, DJ, Milbrandt, J, Milgrom, E, Moore, DD, O'Malley, B, Parker, M, Parker, K, Perlmann, T, Pfahl, M, Rosenfeld, MG, Samuels, H, Schutz, G, Sladek, FM, Stunnenberg, HG, Spedding, M, Thummel, C, Tsai, MJ, Umesono, K, Vennstrom, B, Wahli, W, Weinberger, C, Willson, TM, Yamamoto, K

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Selective Thyroid Hormone Receptor-β Activation: A Strategy for Reduction of Weight, Cholesterol, and Lipoprotein (a) with Reduced Cardiovascular Liability by Grover, Gary J., Mellström, Karin, Ye, Liu, Malm, Johan, Li, Yi-Lin, Bladh, Lars-Göran, Sleph, Paul G., Smith, Mark A., George, Rocco, Vennström, Björn, Mookhtiar, Kasim, Horvath, Ryan, Speelman, Jessica, Egan, Donald, Baxter, John D.

“…Few treatments for obesity exist and, whereas efficacious therapeutics for hyperlipidemia are available, further improvements are desirable. Thyroid hormone…”
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Requirement for Thyroid Hormone Receptor β in T 3 Regulation of Cholesterol Metabolism in Mice by Gullberg, Hjalmar, Rudling, Mats, Saltó, Carmen, Forrest, Douglas, Angelin, Bo, Vennström, Björn

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Lack of thyroid hormone receptor A is associated with selective alterations in behavior and hippocampal circuits by Guadaño-Ferraz, A, Benavides-Piccione, R, Venero, C, Lancha, C, Vennström, B, Sandi, C, DeFelipe, J, Bernal, J

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Identification of Rev-erbα as a physiological repressor of apoC-III gene transcription by Raspé, Eric, Duez, Hélène, Mansén, Anethe, Fontaine, Coralie, Fiévet, Catherine, Fruchart, Jean-Charles, Vennström, Bjorn, Staels, Bart

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Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1 by Wikström, L, Johansson, C, Saltó, C, Barlow, C, Campos Barros, A, Baas, F, Forrest, D, Thorén, P, Vennström, B

“…Thyroid hormone, acting through several nuclear hormone receptors, plays important roles in thermogenesis, lipogenesis and maturation of the neonatal brain…”
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Retardation of Cochlear Maturation and Impaired Hair Cell Function Caused by Deletion of All Known Thyroid Hormone Receptors by Rusch, Alfons, Ng, Lily, Goodyear, Richard, Oliver, Dominik, Lisoukov, Igor, Vennstrom, Bjorn, Richardson, Guy, Kelley, Matthew W, Forrest, Douglas

“…The deafness caused by early onset hypothyroidism indicates that thyroid hormone is essential for the development of hearing. We investigated the underlying…”
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Normal timing of oligodendrocyte development depends on thyroid hormone receptor alpha 1 (TRα1) by Billon, Nathalie, Jolicoeur, Christine, Tokumoto, Yasuhito, Vennström, Björn, Raff, Martin

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Thyroid Hormone Receptor Expression in the Human Hypothalamus and Anterior Pituitary by Alkemade, Anneke, Vuijst, Chrétienne L., Unmehopa, Unga A., Bakker, Onno, Vennström, Björn, Wiersinga, Wilmar M., Swaab, Dick F., Fliers, Eric

“…In the present study, we describe for the first time the distribution of thyroid hormone receptor (TR) isoforms in the human postmortem hypothalamus and…”
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Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbAα orphan receptor by Chomez, Patrick, Neveu, Isabelle, Mansén, Anethe, Kiesler, Eva, Larsson, Lars, Vennström, Björn, Arenas, Ernest

“…ABSTRACT The rev-erbAα gene, belonging to the steroid receptor superfamily of transcription factors, is highly conserved during evolution but little is known…”
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Increased adipogenesis in bone marrow but decreased bone mineral density in mice devoid of thyroid hormone receptors by Kindblom, Jenny M., Gevers, Evelien F., Skrtic, Sofia Movérare, Lindberg, Marie K., Göthe, Sten, Törnell, Jan, Vennström, Björn, Ohlsson, Claes

“…Mice deficient for all known thyroid hormone receptors, TRα1−/−β−/− mice, display a clear skeletal phenotype characterized by growth retardation, delayed…”
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Zonal expression of the thyroid hormone receptor alpha isoforms in rodent liver by Zandieh-Doulabi, B, Dop, E, Schneiders, M, Schiphorst, MP, Mansen, A, Vennstrom, B, Dijkstra, CD, Bakker, O, Wiersinga, WM

“…Many metabolic processes occur simultaneously in the liver in different locations along the porto-central axis of the liver units. These processes are often…”
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Thyroid Hormone Receptor β -dependent Expression of a Potassium Conductance in Inner Hair Cells at the Onset of Hearing by Rusch, Alfons, Erway, Lawrence C., Oliver, Dominik, Vennstrom, Bjorn, Forrest, Douglas

“…To elucidate the role of thyroid hormone receptors (TRs) α 1 and β in the development of hearing, cochlear functions have been investigated in mice lacking TRα…”
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