Search Results - "VENKATACHALAM, T"

NMR and DFT investigations of structure of colchicine in various solvents including density functional theory calculations by Pierens, Gregory K., Venkatachalam, T. K., Reutens, David C.

“…A detailed NMR investigation of the chemical shifts of hydrogen and carbon atoms associated with the structure of the naturally occurring alkaloid colchicine…”
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Computational investigation of binding mechanism of substituted pyrazinones targeting corticotropin releasing factor-1 receptor deliberated for anti-depressant drug design by Shekhar, Mishra Shashank, Venkatachalam, T., Sharma, Chandra Shekhar, Pratap Singh, Hemendra, Kalra, Sourav, Kumar, Neeraj

“…In spite of various research investigations towards anti-depressant drug discovery program, no one drug has not yet launched last 20 years…”
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Effect of stereochemistry on the anti-HIV activity of chiral thiourea compounds by Venkatachalam, T.K, Mao, C, Uckun, Fatih.M

“…Chiral derivatives of several substituted halopyridyl and thiazolyl PETT compounds were synthesized as non-nucleoside inhibitors of the reverse transcriptase…”
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BIN1 in the Pursuit of Ousting the Alzheimer’s Reign: Impact on Amyloid and Tau Neuropathology by Kaur, Ishnoor, Behl, Tapan, Sundararajan, G., Panneerselvam, P., Vijayakumar, A. R., Senthilkumar, G. P., Venkatachalam, T., Jaglan, Dharmender, Yadav, Shivam, Anwer, Khalid, Fuloria, Neeraj Kumar, Sehgal, Aayush, Gulati, Monica, Chigurupati, Sridevi

“…Alzheimer’s disease contributes to 60–70% of all dementia cases in the general population. Belonging to the BIN1/amphiphysin/RVS167 (BAR) superfamily, the…”
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Synthesis, NMR structural characterization and molecular modeling of substituted thiosemicarbazones and semicarbazones using DFT calculations to prove the syn/anti isomer formation by Venkatachalam, T. K., Pierens, Gregory K., Reutens, David C.

“…Thiosemicarbazones possessing electron‐donating and electron‐withdrawing groups were prepared, and their spectral characteristics determined. In all cases, the…”
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Structural, optical, morphological and thermal properties of TiO 2 –Al and TiO 2 –Al 2 O 3 composite powders by ball milling by Mahalingam, T., Selvakumar, C., Ranjith Kumar, E., Venkatachalam, T.

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Genetic Variants in PHACTR1 & LPL Mediate Restenosis Risk in Coronary Artery Patients by Al Hageh, Cynthia, Chacar, Stephanie, Venkatachalam, Thenmozhi, Gauguier, Dominique, Abchee, Antoine, Chammas, Elie, Hamdan, Hamdan, O'Sullivan, Siobhan, Zalloua, Pierre, Nader, Moni

“…Coronary artery disease (CAD) is a major cause of death worldwide. Revascularization via stent placement or coronary artery bypass grafting (CABG) are standard…”
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Molecular pathways and therapeutic strategies in dermatofibrosarcoma protuberans (DFSP): unravelling the tumor's genetic landscape by Singh, Harpreet, Choudhary, Heena Bholaram, Mandlik, Deepa Satish, Magre, Manoj Subhash, Mohanto, Sourav, Ahmed, Mohammed Gulzar, Singh, Bhuvnesh Kumar, Mishra, Arun Kumar, Kumar, Arvind, Mishra, Amrita, Venkatachalam, T, Chopra, Hitesh

“…Dermatofibrosarcoma Protuberans (DFSP) is a rare soft tissue sarcoma distinguished by its infiltrative growth pattern and recurrence potential. Understanding…”
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Comparison of experimental and DFT-calculated NMR chemical shifts of 2-amino and 2-hydroxyl substituted phenyl benzimidazoles, benzoxazoles and benzothiazoles in four solvents using the IEF-PCM solvation model by Pierens, Gregory K., Venkatachalam, T. K., Reutens, David C.

“…A comparative study of experimental and calculated NMR chemical shifts of six compounds comprising 2‐amino and 2‐hydroxy phenyl…”
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Experimental and theoretical investigations of structural and optical properties of CIGS thin films by Chandramohan, M., Velumani, S., Venkatachalam, T.

“…Experimental and theoretical studies of the structural and optical properties of Copper Indium Gallium diSelenide thin films have been performed. Thin films of…”
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The Design, Synthesis, and Evaluation of Diaminopimelic Acid Derivatives as Potential dapF Inhibitors Preventing Lysine Biosynthesis for Antibacterial Activity by Shaikh, Mohd Sayeed, Kale, Mayura A., Muralidharan, V., Venkatachalam, T., Ali, Syed Sarfaraz, Islam, Fahadul, Khan, Sharuk L., Siddiqui, Falak A., Urmee, Humaira, Tapadiya, Ganesh G., Dhawale, Sachin A., Ming, Long Chiau, Ibrahim, Ibrahim Abdel Aziz, Alzahrani, Abdullah R., Sarker, Md. Moklesur Rahman, Azlina, Mohd Fahami Nur

“…We created thiazole and oxazole analogues of diaminopimelic acid (DAP) by replacing its carboxyl groups and substituting sulphur for the central carbon atom…”
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Structural and thermo-optic studies on linear double hydrogen bonded ferroelectric liquid crystal homologous series by Mahalingam, T., Venkatachalam, T., Jayaprakasam, R., Vijayakumar, V. N.

“…A novel series of supramolecular hydrogen bonded ferroelectric liquid crystal (HBFLC) is formed through hydrogen bonding interaction between nonmesogenic…”
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Design and synthesis of hydrogen bonded binary mixture liquid crystals by Mahalingam, T, Venkatachalam, T, Jayaprakasam, R, Vijayakumar, V N

“…An intermolecular hydrogen bond is formed between 4-undecyloxy benzoic acid (11BAO) and cholesteryl acetate (CHA) which has been confirmed by Fourier transform…”
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Radiolabeling of protected tryptophan with [18F]fluoromethyl tosylate: Formation of [18F]fluoromethyl ester of tryptophan instead of 1-N-[18F]fluoromethyl tryptophan methylester by Venkatachalam, T.K., Stimson, D.H.R., Frisch, K., Pierens, G.K., Bhalla, R., Reutens, D.C.

“…The reaction of [18F]fluoromethyl tosylate with methyl(tert-butoxycarbonyl)-l-tryptophanate results in formation the O-alkylated ester of the tryptophan…”
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A comparative study between para-aminophenyl and ortho-aminophenyl benzothiazoles using NMR and DFT calculations by Pierens, G. K., Venkatachalam, T. K., Reutens, D.

“…Ortho‐substituted and para‐substituted aminophenyl benzothiazoles were synthesised and characterised using NMR spectroscopy. A comparison of the proton…”
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NMR, X-Ray Crystal Structure Studies and Mechanism for Formation of a Novel Di-gallium Complex and 5-Methoxy-4,5,6-triphenyl-4,5-dihydro-1,2,4-triazene-3(2H)-thione by Venkatachalam, T. K., Bernhardt, Paul V., Pierens, G. K., Reutens, D. C.

“…Gallium complexes of bis-thiosemicarbazones were prepared and characterized using NMR and X-ray crystallography. Formation of a gallium nitrate complex was…”
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Challenges in the automated synthesis of [ 18 F]-1-fluoroethyl tryptophan: Formation of both O- and N-alkylated products by Venkatachalam, T K, Stimson, D H R, Pierens, G K, Bhalla, R, Reutens, D C

“…[ F]Fluoroethyl tosylate was synthesized using an automated "Synthra" module using ethylene di-tosylate and [ F]fluoride/K /K CO in acetonitrile. […”
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Heteronuclear NMR spectroscopic investigations of hydrogen bonding in 2-(benzo[d]thiazole-2′-yl)-N-alkylanilines by Venkatachalam, T. K., Pierens, G. K., Bernhardt, P. V., Reutens, D. C.

“…The 2‐(benzo[d]thiazole‐2′‐yl)‐N‐alkylanilines have previously revealed the presence of a strong intramolecular hydrogen bond. This in turn gives rise to a…”
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Synthesis and X-ray Crystal Structure of 2 and 4-Trifluoromethyl Substituted Phenyl Semicarbazone and Thiosemicarbazone by Venkatachalam, T. K., Bernhardt, Paul V., Pierens, Gregory K., Reutens, David C.

“…NMR and single crystal X-ray structure data for four structurally similar semicarbazones and thiosemicarbazones were compared. In solution, proton NMR showed…”
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Band structure calculations of Cu(In1−xGax)Se2 by Chandramohan, M., S.Velumani, Venkatachalam, T.

“…First principles density calculations of the band structure, and density of states of the Cu(In1ax Ga x )Se2 in the chalcopyrite type structure have been…”
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