Search Results - "VELAYUDHAN, Jyoti"

Fosfomycin Enhances the Active Transport of Tobramycin in Pseudomonas aeruginosa by MACLEOD, David L, VELAYUDHAN, Jyoti, KENNEY, Thomas F, THERRIEN, Joseph H, SUTHERLAND, Jennifer L, BARKER, Lynn M, BAKER, William R

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l-Serine Catabolism via an Oxygen-Labile l-Serine Dehydratase Is Essential for Colonization of the Avian Gut by Campylobacter jejuni by VELAYUDHAN, Jyoti, JONES, Michael A, BARROW, Paul A, KELLY, David J

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Analysis of gluconeogenic and anaplerotic enzymes in Campylobacter jejuni: an essential role for phosphoenolpyruvate carboxykinase by Velayudhan, Jyoti, Kelly, David J

“…Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK 1 Author for correspondence: David…”
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Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high‐affinity ferrous iron transporter by Velayudhan, Jyoti, Hughes, Nicky J., McColm, Andrew A., Bagshaw, Julie, Clayton, Chris L., Andrews, Simon C., Kelly, David J.

“…The genome sequence of Helicobacter pylori suggests that this bacterium possesses several Fe acquisition systems, including both Fe2+‐ and Fe3+‐citrate…”
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Essential Role of Ferritin Pfr in Helicobacter pylori Iron Metabolism and Gastric Colonization by WAIDNER, Barbara, GREINER, Stefan, KUSTERS, Johannes G, KELLY, David J, HAAS, Rainer, KIST, Manfred, BERESWILL, Stefan, ODENBREIT, Stefan, KAVERMANN, Holger, VELAYUDHAN, Jyoti, STÄHLER, Frank, GUHL, Johannes, BISSE, Emmenuel, VAN VLIET, Arnoud H. M, ANDREWS, Simon C

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Demonstration of Functional Similarity of Proposed Biosimilar ABP 501 to Adalimumab by Velayudhan, Jyoti, Chen, Yuh-feng, Rohrbach, Amanda, Pastula, Christina, Maher, Gwen, Thomas, Heather, Brown, Ryan, Born, Teresa L.

“…Background Due to the complex molecular structure and proprietary manufacturing processes of monoclonal antibodies (mAbs), differences in structure and…”
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Abstract 221: Tisotumab vedotin induces anti-tumor activity through MMAE-mediated, Fc-mediated, and Fab-mediated effector functions in vitro by Alley, Stephen C., Harris, Jeffrey R., Cao, Anthony, Heuvel, Elke Gresnigt-van den, Velayudhan, Jyoti, Satijn, David, Verploegen, Sandra, Dominguez, Teresa, Breij, Esther C.

“…Abstract Tisotumab vedotin is an antibody-drug conjugate composed of a human IgG targeting tissue factor (TF), a valine citruline linker, and the microtubule…”
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Distinct roles of the Salmonella enterica serovar Typhimurium CyaY and YggX proteins in the biosynthesis and repair of iron-sulfur clusters by Velayudhan, Jyoti, Karlinsey, Joyce E, Frawley, Elaine R, Becker, Lynne A, Nartea, Margaret, Fang, Ferric C

“…Labile [4Fe-4S](2+) clusters found at the active sites of many dehydratases are susceptible to damage by univalent oxidants that convert the clusters to an…”
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Characterizing the effect of multiple Fc glycan attributes on the effector functions and FcγRIIIa receptor binding activity of an IgG1 antibody by Pace, Danielle, Lewis, Nathaniel, Wu, Tina, Gillespie, Ron, Leiske, Dan, Velayudhan, Jyoti, Rohrbach, Amanda, Connell-Crowley, Lisa

“…N‐linked Fc glycosylation of IgG1 monoclonal antibody therapeutics can directly influence their mechanism of action by impacting IgG effector functions such as…”
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role of ferritins in the physiology of Salmonella enterica sv. Typhimurium: a unique role for ferritin B in iron-sulphur cluster repair and virulence by Velayudhan, Jyoti, Castor, Margaret, Richardson, Anthony, Main-Hester, Kara L, Fang, Ferric C

“…Ferritins are ubiquitous iron (Fe) storage proteins that play a fundamental role in cellular Fe homeostasis. The enteric pathogen Salmonella enterica serovar…”
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Characterizing the effect of multiple Fc glycan attributes on the effector functions and Fc[gamma]RIIIa receptor binding activity of an IgG1 antibody by Pace, Danielle, Lewis, Nathaniel, Wu, Tina, Gillespie, Ron, Leiske, Dan, Velayudhan, Jyoti, Rohrbach, Amanda, Connell-Crowley, Lisa

“…N-linked Fc glycosylation of IgG1 monoclonal antibody therapeutics can directly influence their mechanism of action by impacting IgG effector functions such as…”
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Acid stress activation of the sigma(E) stress response in Salmonella enterica serovar Typhimurium by Muller, Cécile, Bang, Iel-Soo, Velayudhan, Jyoti, Karlinsey, Joyce, Papenfort, Kai, Vogel, Jörg, Fang, Ferric C

“…The alternative sigma factor sigma(E) is activated by unfolded outer membrane proteins (OMPs) and plays an essential role in Salmonella pathogenesis. The…”
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Results of functional testing and pharmacokinetics comparing ABP 215 to bevacizumab by Markus, Richard, Kaur, Primal, Chow, Vincent, Zhang, Nan, Born, Teresa, Huynh, Quyen, Maher, Gwen, Velayudhan, Jyoti, Howard, Monique, Reynhardt, Kaz, Goletz, Theresa

“…Abstract only 711 Background: ABP 215 is a biosimilar candidate to bevacizumab (BEV), a monoclonal antibody (mAb) that binds and inhibits vascular endothelial…”
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The criticality of high-resolution N-linked carbohydrate assays and detailed characterization of antibody effector function in the context of biosimilar development by Brady, Lowell J, Velayudhan, Jyoti, Visone, Devi B, Daugherty, Ken C, Bartron, Jeff L, Coon, Michael, Cornwall, Cabot, Hinckley, Peter J, Connell-Crowley, Lisa

“…Accurate measurement and functional characterization of antibody Fc domain N-linked glycans is critical to successful biosimilar development. Here, we describe…”
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Alternative sigma factor interactions in Salmonella: sigma and sigma promote antioxidant defences by enhancing sigma levels by Bang, Iel-Soo, Frye, Jonathan G, McClelland, Michael, Velayudhan, Jyoti, Fang, Ferric C

“…Hierarchical interactions between alternative sigma factors control sequential gene expression in Gram-positive bacteria, whereas alternative sigma factors in…”
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Acid stress activation of the sE stress response in Salmonella enterica serovar Typhimurium by Muller, Cecile, Bang, Iel-Soo, Velayudhan, Jyoti, Karlinsey, Joyce, Papenfort, Kai, Vogel, Joerg, Fang, Ferric C

“…SummaryThe alternative sigma factor sE is activated by unfolded outer membrane proteins (OMPs) and plays an essential role in Salmonella pathogenesis. The…”
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Acid stress activation of the [sigma]^sup E^ stress response in Salmonella enterica serovar Typhimurium by Muller, Cécile, Bang, Iel-Soo, Velayudhan, Jyoti, Karlinsey, Joyce, Papenfort, Kai, Vogel, Jörg, Fang, Ferric C

“…The alternative sigma factor ... is activated by unfolded outer membrane proteins (OMPs) and plays an essential role in Salmonella pathogenesis. The canonical…”
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Acid stress activation of the [sigma]^sup E^ stress response in Salmonella enterica serovar Typhimurium by Muller, Cécile, Bang, Iel-Soo, Velayudhan, Jyoti, Karlinsey, Joyce, Papenfort, Kai, Vogel, Jörg, Fang, Ferric C

“…The alternative sigma factor ... is activated by unfolded outer membrane proteins (OMPs) and plays an essential role in Salmonella pathogenesis. The canonical…”
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Acid stress activation of the σE stress response in Salmonella enterica serovar Typhimurium by Muller, Cécile, Bang, Iel-Soo, Velayudhan, Jyoti, Karlinsey, Joyce, Papenfort, Kai, Vogel, Jörg, Fang, Ferric C

“…The alternative sigma factor σE is activated by unfolded outer membrane proteins (OMPs) and plays an essential role in Salmonella pathogenesis. The canonical…”
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Alternative sigma factor interactions in Salmonella: [sigma]^sup E^ and [sigma]^sup H^ promote antioxidant defences by enhancing [sigma]^sup S^ levels by Iel-Soo Bang, Frye, Jonathan G, McClelland, Michael, Velayudhan, Jyoti, Fang, Ferric C

“…Hierarchical interactions between alternative sigma factors control sequential gene expression in Gram-positive bacteria, whereas alternative sigma factors in…”
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