Search Results - "VAZQUEZ, VINÍCIUS DE LIMA"
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Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation
Published in Pharmacological research (01-09-2016)“…[Display omitted] The BRAFV600E mutation confers constitutive kinase activity and accounts for >90% of BRAF mutations in melanoma. This genetic alteration is a…”
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Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure
Published in Nature communications (15-07-2022)“…Ultraviolet radiation (UV) is causally linked to cutaneous melanoma, yet the underlying epigenetic mechanisms, known as molecular sensors of exposure, have not…”
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3
Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line
Published in Human cell : official journal of Human Cell Research Society (2024)“…Cutaneous squamous cell carcinoma (cSCC) is a common type of skin cancer that can result in significant morbidity, although it is usually well-managed and…”
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Circulating tumor DNA (ctDNA) detection is associated with shorter progression-free survival in advanced melanoma patients
Published in Scientific reports (29-10-2020)“…BRAF , NRAS and TERT mutations occur in more than 2/3 of melanomas. Its detection in patient’s blood, as circulating tumor DNA (ctDNA), represents a…”
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Caution is needed in interpreting the results of comparative studies regarding oncological operations by minimally invasive versus laparotomic access
Published in Revista do Colégio Brasileiro de Cirurgiões (2020)“…ABSTRACT We aim to alert the difference between groups while comparing studies of abdominal oncological operations performed either by minimally invasive or…”
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Is the gastrointestinal stromal tumor arising in the rectovaginal septum an extragastrointestinal entity? A time for reflection
Published in International journal of colorectal disease (01-03-2011)Get full text
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Association of Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Genetic Variants with Risk and Outcome of Cutaneous Melanoma
Published in International journal of molecular sciences (17-11-2024)“…This study aimed to verify whether germline single nucleotide variants (SNV) in CTLA-4 gene, c.-1765C>T, c.-1661A>G, c.-1577G>A, and c.-1478G>A, influence the…”
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Clinical characterization of the Dermatofibrosarcomas at Barretos Cancer Hospital in São Paulo
Published in Brazilian Journal of Oncology (01-12-2022)“…Introduction: Dermatofibrosarcoma (DFSP) is a rare neoplasia from mesenchymal tissues in the skin. It has a high potential for local invasion and a high rate…”
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PD-1/PD-L1 and VEGF-A/VEGF-C expression in lymph node microenvironment and association with melanoma metastasis and survival
Published in Melanoma research (01-12-2017)“…Regional lymph nodes are affected frequently by melanoma metastasis. Its microenvironment may be associated with tumor progression. We investigated sentinel…”
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TNFRSF1B Gene Variants in Clinicopathological Aspects and Prognosis of Patients with Cutaneous Melanoma
Published in International journal of molecular sciences (01-03-2024)“…Regulatory T lymphocytes play a critical role in immune regulation and are involved in the aberrant cell elimination by facilitating tumor necrosis factor…”
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Indoleamine 2,3-dioxygenase in melanoma progression and BRAF inhibitor resistance
Published in Pharmacological research (01-09-2020)“…[Display omitted] Indoleamine 2,3-dioxygenase (IDO) is associated with the progression of many types of tumors, including melanoma. However, there is limited…”
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Prognostic factors for lymph node metastasis from advanced squamous cell carcinoma of the skin of the trunk and extremities
Published in World journal of surgical oncology (04-07-2008)“…Squamous cell carcinoma (SCC) of the skin of the trunk and extremities may present lymph node metastasis with difficult disease control and poor survival. The…”
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Brazilian Society of Surgical Oncology recommendations on Merkel cell carcinoma surgical treatment
Published in Journal of surgical oncology (01-09-2024)“…Background Merkel cell carcinoma (MCC) is a rare neuroendocrine skin cancer with poor 5‐year survival rates. Surgery and radiation are the current first‐line…”
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14
Síndrome de Boerhaave: relato de caso
Published in Revista do Colégio Brasileiro de Cirurgiões (01-02-2013)“…Spontaneous esophageal rupture carries high morbidity and mortality. The main prognostic factor is early diagnosis, before 12 hours, and appropriate treatment…”
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Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas
Published in Melanoma research (01-04-2016)“…Acral lentiginous melanoma (ALM) is the less common subtype with singular characterization. TERT (human telomerase reverse transcriptase) promoter mutations…”
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PD-L1 Tumor Expression as a Predictive Biomarker of Immune Checkpoint Inhibitors' Response and Survival in Advanced Melanoma Patients in Brazil
Published in Diagnostics (Basel) (01-03-2023)“…Immune checkpoint blockade (ICB) agents are prominent immunotherapies for the treatment of advanced melanoma. However, they fail to promote any durable…”
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TNFRSF1B GENE VARIANTS IN RISK AND CLINICOPATHOLOGICAL ASPECTS OF PATIENTS WITH CUTANEOUS MELANOMA
Published in Hematology, Transfusion and Cell Therapy (01-04-2024)“…Introduction/Justification: Cutaneous melanoma (CM) is a low incidence tumor worldwide but is associated with high mortality. Skin exposure to ultraviolet…”
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Sociodemographic effect on stage at diagnosis of melanoma patients treated in a public cancer center in Brazil
Published in Brazilian Journal of Oncology (01-10-2023)“…INTRODUCTION: Melanoma is the most aggressive type of skin cancer, with a continuous increase in its incidence worldwide. The prognosis of patients is…”
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Characteristics of Brazilian melanomas: real-world results before and after the introduction of new therapies
Published in BMC research notes (28-05-2019)“…This study is a characterization of the treatment patterns and outcomes of a Brazilian melanoma cohort collected of 1848 patients enrolled between 1996 and…”
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20
Xiphoidectomy
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-06-2003)“…Complex surgical procedures in the upper abdomen required ear exposure. To improve exposure xiphoidectomy is indicated; however, in the past there was an…”
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