Search Results - "VAUGHAN, D. E."

PAI‐1 and atherothrombosis by VAUGHAN, D. E.

“…Plasminogen activator inhibitor‐1 (PAI‐1) is the major physiologic inhibitor of tissue‐type plasminogen activator in plasma, and is elevated in a variety of…”
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Anatomic Restoration Technique of Continence Mechanism and Preservation of Puboprostatic Collar: A Novel Modification to Achieve Early Urinary Continence in Men Undergoing Robotic Prostatectomy by Tewari, Ashutosh K, Bigelow, Kevin, Rao, Sandhya, Takenaka, Atsushi, El-Tabi, Nasr, Te, Alex, Vaughan, E.D

“…Objectives The puboprostatic ligaments, puboperinealis muscle, and arcus tendineus are all recognized as important for continence in men and women. This…”
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Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury by Ma, J., Weisberg, A., Griffin, J.P., Vaughan, D.E., Fogo, A.B., Brown, N.J.

“…This study tests the hypothesis that plasminogen activator inhibitor-1 (PAI-1) contributes to aldosterone-induced renal and cardiac injury. The effects of…”
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Cervical lymph node metastasis in oral cancer: the importance of even microscopic extracapsular spread by Woolgar, J.A., Rogers, S.N., Lowe, D., Brown, J.S., Vaughan, E.D.

“…The prognostic significance of extracapsular spread of cervical metastases in oral cancer is still controversial. To investigate the importance of extent of…”
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Promoter methylation of P16, RARβ, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing by Shaw, R J, Liloglou, T, Rogers, S N, Brown, J S, Vaughan, E D, Lowe, D, Field, J K, Risk, J M

“…Methylation profiling of cancer tissues has identified this mechanism as an important component of carcinogenesis. Epigenetic silencing of tumour suppressor…”
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Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction by El Chaar, Maher, Chen, Jie, Seshan, Surya V, Jha, Sharda, Richardson, Ingride, Ledbetter, Steven R, Vaughan, Jr, E D, Poppas, Dix P, Felsen, Diane

“…In unilateral ureteral obstruction (UUO), the kidney is characterized by increased fibrosis and apoptosis. Both transforming growth factor-beta (TGF-beta) and…”
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New Synthesis and Insight into the Structure of Blue Ultramarine Pigments by Arieli, D, Vaughan, D. E. W, Goldfarb, D

“…A new and easy method for preparing blue sodalite pigments which involves high-temperature calcination of sodalite samples synthesized with aluminum sulfate…”
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Diagnosis of renal tumors on needle biopsy specimens by histological and molecular analysis by Barocas, D A, Rohan, S M, Kao, J, Gurevich, R D, Del Pizzo, J J, Vaughan, Jr, E D, Akhtar, M, Chen, Y-T, Scherr, D S

“…We diagnosed the subtypes of renal cell carcinoma on needle core biopsies using a combination of histopathology and a molecular diagnostic algorithm. Core…”
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Angiotensin-converting enzyme inhibitors by BROWN, N. J, VAUGHAN, D. E

“…ACE inhibitors have achieved widespread usage in the treatment of cardiovascular and renal disease. ACE inhibitors alter the balance between the…”
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The influence of allogenic blood transfusion in patients having free-flap primary surgery for oral and oropharyngeal squamous cell carcinoma by SZAKMANY, T, DODD, M, DEMPSEY, G. A, LOWE, D, BROWN, I. S, VAUGHAN, E. D, ROGERS, S. N

“…The influence of perioperative blood transfusion in oral and oropharyngeal squamous cell carcinoma remains uncertain. It is believed that blood transfusion…”
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Factors that influence the outcome of salvage in free tissue transfer by Brown, J.S, Devine, J.C, Magennis, P, Sillifant, P, Rogers, S.N, Vaughan, E.D

“…Introduction: The success of salvage techniques for free tissue transfer is well documented. The aim of this study was to identify factors that influenced the…”
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Angiotensin receptor blockade decreases fibrosis and fibroblast expression in a rat model of unilateral ureteral obstruction by Kellner, Daniel, Chen, Jie, Richardson, Ingride, Seshan, Surya V, El Chaar, Maher, Vaughan, Jr, E D, Poppas, Dix, Felsen, Diane

“…Unilateral ureteral obstruction is characterized by histopathological changes including interstitial fibrosis, fibroblast specific protein expression, tubular…”
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The prognostic implications of the surgical margin in oral squamous cell carcinoma by Sutton, D.N, Brown, J.S, Rogers, S.N, Vaughan, E.D, Woolgar, J.A

“…The prime objective of tumour ablation in oral squamous cell carcinoma (OSCC) is the removal, with a ‘margin’ of normal tissue, of the whole tumour. Definition…”
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An assessment of deprivation as a factor in the delays in presentation, diagnosis and treatment in patients with oral and oropharyngeal squamous cell carcinoma by Rogers, S.N, Pabla, R, McSorley, A, Lowe, D, Brown, J.S, Vaughan, E.D

“…Summary This study explores the relationship between deprivation and patient and professional delays in presentation and treatment of oral and oropharyngeal…”
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A comparison of outcomes for patients with oral squamous cell carcinoma at intermediate risk of recurrence treated by surgery alone or with post-operative radiotherapy by Brown, J.S, Blackburn, T.K, Woolgar, J.A, Lowe, D, Errington, R.D, Vaughan, E.D, Rogers, S.N

“…Summary Controversy remains about which patients at intermediate risk of recurrence of oral squamous cell carcinoma would benefit from radiotherapy. A…”
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Transgenic over-expression of plasminogen activator inhibitor-1 results in age-dependent and gender-specific increases in bone strength and mineralization by Nordstrom, S.M, Carleton, S.M, Carson, W.L, Eren, M, Phillips, C.L, Vaughan, D.E

“…Abstract The plasminogen activation system (PAS) and its principal inhibitor, plasminogen activator inhibitor-1 (PAI-1), are recognized modulators of matrix…”
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Prognostic importance of site in squamous cell carcinoma of the buccal mucosa by Shaw, R.J, McGlashan, G, Woolgar, J.A, Lowe, D, Brown, J.S, Vaughan, E.D, Rogers, S.N

“…Abstract While stage and grade of oral cancer have a profound and well-recognised influence on outcome, the effect of site is less clear and there have been…”
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Trends in head and neck microvascular reconstructive surgery in Liverpool (1992–2001) by Brown, J.S., Magennis, P., Rogers, S.N., Cawood, J.I., Howell, R., Vaughan, E.D.

“…Microvascular reconstructive techniques in head and neck surgery are well established, but we are now entering an era of modification exemplified by perforator…”
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Survival and patterns of recurrence in 200 oral cancer patients treated by radical surgery and neck dissection by Woolgar, J.A, Rogers, S, West, C.R, Errington, R.D, Brown, J.S, Vaughan, E.D

“…The outcome of 200 patients with squamous cell carcinoma of the oral/oropharyngeal mucosa managed by primary radical surgery and simultaneous neck dissection…”
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Male-female differences in the genetic regulation of t-PA and PAI-1 levels in a Ghanaian population by Schoenhard, J. A, Asselbergs, F. W, Poku, K. A, Stocki, S. A, Gordon, S, Vaughan, D. E, Brown, N. J, Moore, J. H, Williams, Scott M

“…Tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) directly influence thrombus formation and degradation, and have been…”
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