Search Results - "VASANDANI, V. M"

Engineering receptor-mediated cytotoxicity into human ribonucleases by steric blockade of inhibitor interaction by Youle, Richard J, Suzuki, Motoshi, Saxena, Shailendra K, Boix, Ester, Prill, Robert J, Vasandani, Veena M, Ladner, Jane E, Sung, Cynthia

“…Several nonmammalian members of the RNase A superfamily exhibit anticancer activity that appears to correlate with resistance to the cytosolic ribonuclease…”
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Reversible nephrotoxicity of onconase and effect of lysine pH on renal onconase uptake by VASANDANI, V. M, BURRIS, J. A, SUNG, C

“…To examine the histopathology of the kidney in mice following repeated injections of the antitumor drug onconase, and to determine whether lysine, which…”
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Molecular determinants in the plasma clearance and tissue distribution of ribonucleases of the ribonuclease A superfamily by VASANDANI, V. M, WU, Y.-N, MIKULSKI, S. M, YOULE, R. J, SUNG, C

“…The similarities and differences among members of the RNase A superfamily provide an ideal opportunity to examine the molecular basis for differences in their…”
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Role of the N Terminus in RNase A Homologues: Differences in Catalytic Activity, Ribonuclease Inhibitor Interaction and Cytotoxicity by Boix, Ester, Wu, YouNeng, Vasandani, Veena M., Saxena, Shailendra K., Ardelt, Wojciech, Ladner, Jane, Youle, Richard J.

“…A number of biochemical properties differ dramatically among homologues within the pancreatic ribonuclease superfamily. Human pancreatic ribonuclease (hRNase)…”
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Liposome immune lysis assay (LILA) for gelonin by Paul, A, Madan, S, Vasandani, V M, Ghosh, P C, Bachhawat, B K

“…A complement-mediated liposome immune lysis assay using entrapped calcein was developed for a plant toxin gelonin. Gelonin was covalently coupled to DPPE, and…”
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Potentiation of ricin cytotoxicity by liposomal monensin under in vitro and in vivo conditions by Madan, S, Vasandani, V M, Ghosh, P C

“…Effect of monensin, intercalated in liposomes on the cytotoxicities of ricin, Pseudomonas exotoxin A and diphtheria toxin in phagocytic and non-phagocytic…”
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Interferon enhances the activity of the anticancer ribonuclease, onconase by Vasandani, V M, Castelli, J C, Hott, J S, Saxena, S, Mikulski, S M, Youle, R J

“…Interferons (IFN) are biologic agents involved in the antiviral response and the inhibition of tumor growth. Biochemical pathways of IFN action include the…”
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In vivo potentiation of ricin toxicity by monensin delivered through liposomes by Vasandani, V M, Madan, S, Ghosh, P C

“…Monensin, a carboxylic ionophore, which is known to raise intravesicular pH, was intercalated in liposomes and its effect on the toxicity of ricin in mice was…”
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