Search Results - "VANEKER, M."

The in vitro mechanisms and in vivo efficacy of intravenous lidocaine on the neuroinflammatory response in acute and chronic pain by van der Wal, S.E.I., van den Heuvel, S.A.S., Radema, S.A., van Berkum, B.F.M., Vaneker, M., Steegers, M.A.H., Scheffer, G.J., Vissers, K.C.P.

“…Introduction The neuroinflammatory response plays a key role in several pain syndromes. Intravenous (iv) lidocaine is beneficial in acute and chronic pain…”
Get full text

Lidocaine increases the anti-inflammatory cytokine IL-10 following mechanical ventilation in healthy mice by VAN DER WAL, S., VANEKER, M., STEEGERS, M., VAN BERKUM, B., KOX, M., VAN DER LAAK, J., VAN DER HOEVEN, J., VISSERS, K., SCHEFFER, G. J.

“…Background Mechanical ventilation (MV) induces an inflammatory response that may result in (acute) lung injury. Lidocaine, an amide local anesthetic, has…”
Get full text

α7 Nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced tumour necrosis factor-α production and lung injury by Kox, M., Pompe, J.C., Peters, E., Vaneker, M., van der Laak, J.W., van der Hoeven, J.G., Scheffer, G.J., Hoedemaekers, C.W., Pickkers, P.

“…Mechanical ventilation (MV) induces an inflammatory response that can lead to lung injury. The vagus nerve can limit the inflammatory response through the…”
Get full text

Cytokines and biotrauma in ventilator-induced lung injury : a critical review of the literature by HALBERTSMA, F. J. J, VANEKER, M, SCHEFFER, C. J, VAN DER HOEVEN, J. G

“…Mechanical ventilation is known to induce and aggravate lung injury. One of the underlying mechanisms is biotrauma, an inflammatory response in which cytokines…”
Get full text

Resveratrol attenuates NF-[kappa]B-binding activity but not cytokine production in mechanically ventilated mice by Wal, S E I, Vaneker, M, Kox, M, Braak, G, Hees, H W H, Brink, I A, Pol, F M, Heunks, L M, Hoeven, J G, Joosten, L A B, Vissers, K C P, Scheffer, G J

“…Background Mechanical ventilation (MV) can result in inflammation and subsequent lung injury. Toll-like receptor (TLR)4 and NF-[kappa]B are proposed to play a…”
Get full text

Polytrauma at the Emergency Department; can we relate arterial blood gas analysis to a shock classification? by Evers, M. J., Vaneker, M., Biert, J.

“…Objective Shock is defined as a change of circulation which results in hypoxia at the tissue level. Lactate and base deficit (BD) are associated with a high…”
Get full text

Patients initially diagnosed as ‘warm’ or ‘cold’ CRPS 1 show differences in central sensory processing some eight years after diagnosis: a quantitative sensory testing study by Vaneker, Michiel, Wilder-Smith, Oliver H.G., Schrombges, Patrick, de Man-Hermsen, Irene, Oerlemans, H. Magreet

“…We used quantitative sensory testing (QST) to gain further insight into mechanisms underlying pain in CRPS 1. Specific goals were: (1) to identify altered…”
Get full text

Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice by VAN DER WAL, S. E. I., VANEKER, M., KOX, M., BRAAK, G., VAN HEES, H. W. H., VAN DEN BRINK, I. A., VAN DE POL, F. M., HEUNKS, L. M., VAN DER HOEVEN, J. G., JOOSTEN, L. A. B., VISSERS, K. C. P., SCHEFFER, G. J.

“…Background Mechanical ventilation (MV) can result in inflammation and subsequent lung injury. Toll‐like receptor (TLR)4 and NF‐κB are proposed to play a…”
Get full text

Isoflurane attenuates pulmonary interleukin-1β and systemic tumor necrosis factor-α following mechanical ventilation in healthy mice by VANEKER, M., SANTOSA, J. P., HEUNKS, L. M., HALBERTSMA, F. J., SNIJDELAAR, D. G., VAN EGMOND, J., VAN DEN BRINK, I. A., VAN DE POL, F. M., VAN DER HOEVEN, J. G., SCHEFFER, G. J.

“…Background: Mechanical ventilation (MV) induces an inflammatory response in healthy lungs. The resulting pro‐inflammatory state is a risk factor for…”
Get full text

Primary respiratory failure in inclusion body myositis by VOERMANS, N. C, VANEKER, M, HENGSTMAN, G. J. D, TER LAAK, H. J, ZIMMERMAN, C, SCHELHAAS, H. J, ZWARTS, M. J

Get full text

Effects of intravenous lidocaine on alfentanil consumption during procedural sedation for colonoscopy in patients with inflammatory bowel disease: a randomized controlled trial by Aalbers, T.T.J., van den Heuvel, S.A.S., Bronkhorst, E.M., van Esch, A.A.J., Scheffer, G.J., Vaneker, M

“…Background: Procedural sedation and analgesia (PSA) is used during colonoscopy to facilitate the procedure and relieve patient’s discomfort. The foremost risk…”
Get full text

Innate immune response-mediated late increase in SuPAR in multi-trauma patients by Timmermans, K, Kox, M, Vaneker, M, Pickkers, P

Get full text

Immune paralysis in trauma patients; implications for prehospital intervention by Kox, M, Timmermans, K, Vaneker, M, Scheffer, GJ, Pickkers, P

Get full text

Toll-like Receptor 4 Signaling in Ventilator-induced Diaphragm Atrophy by SCHELLEKENS, Willem-Jan M, VAN HEES, Hieronymus W. H, VANEKER, Michiel, LINKELS, Marianne, RICHARD DEKHUIJZEN, P. N, JAN SCHEFFER, Gert, DER HOEVEN, Johannes G. Van, HEUNKS, Leo M. A

“…Mechanical ventilation induces diaphragm muscle atrophy, which plays a key role in difficult weaning from mechanical ventilation. The signaling pathways…”
Get full text

Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity : An in vivo model using clinical relevant ventilation settings by VANEKER, Michiel, HALBERTSMA, Feico J, VAN EGMOND, Jan, NETEA, Mihai G, DIJKMAN, Henry B, SNIJDELAAR, Dirk G, JOOSTEN, Leo A, VAN DER HOEVEN, Johannes G, JAN SCHEFFER, Gert

“…Mechanical ventilation (MV) may activate the innate immune system, causing the release of cytokines. The resulting proinflammatory state is a risk factor for…”
Get full text

Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice by Vaneker, Michiel, Joosten, Leo A, Heunks, Leo M A, Snijdelaar, Dirk G, Halbertsma, Feico J, van Egmond, Jan, Netea, Mihai G, van der Hoeven, Johannes G, Scheffer, Gert Jan

“…Mechanical ventilation (MV) can induce ventilator-induced lung injury. A role for proinflammatory pathways has been proposed. The current studies analyzed the…”
Get full text

Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice: Resveratrol in a mouse model of MV by VAN DER WAL, S. E. I., VANEKER, M., KOX, M., BRAAK, G., VAN HEES, H. W. H., VAN DEN BRINK, I. A., VAN DE POL, F. M., HEUNKS, L. M., VAN DER HOEVEN, J. G., JOOSTEN, L. A. B., VISSERS, K. C. P., SCHEFFER, G. J.

Get full text

PS2-044. Bypassing the inflammasome: crucial role for neutrophil serine proteases in ventilator-induced lung injury by Timmermans, K., van der Wal, S.E.I., Vaneker, M., Kox, M., Braak, G.J.J., van der Laak, J.A.W.M., Netea, M.G., van der Hoeven, J.G., Joosten, L.A.B., Scheffer, G.J.

Get full text

Impairments as measured by ISS do not greatly change between one and eight years after CRPS 1 diagnosis by Vaneker, Michiel, Wilder-Smith, Oliver H.G., Schrombges, Patrick, Oerlemans, H. Margreet

“…Complex Regional Pain Syndrome type 1 (CRPS 1) is a potentially incapacitating complication in which pain seems to be the most disabling factor. We performed a…”
Get full text

The selective α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced inflammation and lung injury by Kox, M, Pompe, JC, Vaneker, M, Heunks, LM, Hoeven, JG, Hoedemaekers, CW, Pickkers, P

Get full text