Search Results - "VANDERVOORT, M. K"

Development of interim patient‐reported outcome measures for the assessment of ulcerative colitis disease activity in clinical trials by Jairath, V., Khanna, R., Zou, G. Y., Stitt, L., Mosli, M., Vandervoort, M. K., D'Haens, G., Sandborn, W. J., Feagan, B. G., Levesque, B. G.

“…Summary Background Patient‐reported outcomes (PROs) have an increasingly important role in the evaluation of new therapies for inflammatory bowel disease. The…”
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A retrospective analysis: the development of patient reported outcome measures for the assessment of Crohn's disease activity by Khanna, R., Zou, G., D'Haens, G., Feagan, B. G., Sandborn, W. J., Vandervoort, M. K., Rolleri, R. L., Bortey, E., Paterson, C., Forbes, W. P., Levesque, B. G.

“…Summary Background The Crohn's Disease Activity Index (CDAI) is a measure of disease activity based on symptoms, signs and a laboratory test. The US Food and…”
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Plasma-exchange therapy in chronic inflammatory demyelinating polyneuropathy : A double-blind, sham-controlled, cross-over study by HAHN, A. F, BOLTON, C. F, PILLAY, N, CHALK, C, BENSTEAD, T, BRIL, V, SHUMAK, K, VANDERVOORT, M. K, FEASBY, T. E

“…Eighteen patients with definite, untreated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) of chronic progressive (nine patients) or relapsing…”
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The development of a magnetic resonance imaging index for fistulising Crohn's disease by Samaan, M. A., Puylaert, C. A. J., Levesque, B. G., Zou, G. Y., Stitt, L., Taylor, S. A., Shackelton, L. M., Vandervoort, M. K., Khanna, R., Santillan, C., Rimola, J., Hindryckx, P., Nio, C. Y., Sandborn, W. J., D'Haens, G., Feagan, B. G., Jairath, V., Stoker, J.

“…Summary Background Magnetic resonance imaging (MRI) is the gold standard for assessment of perianal fistulising Crohn's disease (CD). The Van Assche index is…”
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Randomised non‐inferiority trial: 1600 mg versus 400 mg tablets of mesalazine for the treatment of mild‐to‐moderate ulcerative colitis by D'Haens, G. R., Sandborn, W. J., Zou, G., Stitt, L. W., Rutgeerts, P. J., Gilgen, D., Jairath, V., Hindryckx, P., Shackelton, L. M., Vandervoort, M. K., Parker, C. E., Muller, C., Pai, R. K., Levchenko, O., Marakhouski, Y., Horynski, M., Mikhailova, E., Kharchenko, N., Pimanov, S., Feagan, B. G.

“…Summary Background High concentration mesalazine formulations are more convenient than conventional low concentration formulations for the treatment of…”
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The impact of blinding on the results of a randomized, placebo-controlled multiple sclerosis clinical trial by Noseworthy, J H, Ebers, G C, Vandervoort, M K, Farquhar, R E, Yetisir, E, Roberts, R

“…In the randomized, placebo-controlled, physician-blinded Canadian cooperative trial of cyclophosphamide and plasma exchange, neither active treatment regimens…”
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Interrater variability with the expanded disability status scale (EDSS) and functional systems(FS) in a multiple sclerosis clinical trial by NOSEWORTHY, J. H, VANDERVOORT, M. K, WONG, C. J, EBERS, G. C

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An open-trial evaluation of mitoxantrone in the treatment of progressive MS by NOSEWORTHY, J. H, HOPKINS, M. B, EBERS, G. C, VANDERVOORT, M. K, KARLIK, S. J, LEE, D. H, PENMAN, M, RICE, G. P. A, GRINWICH, K. D, CAUVIER, H, HARRIS, B. J

“…We treated 13 patients with progressive MS with mitoxantrone. All patients received a standard IV dose of mitoxantrone (8 mg/m2) every 3 weeks for a total of…”
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Serial cranial and spinal cord magnetic resonance imaging in multiple sclerosis by Wiebe, S, Lee, D H, Karlik, S J, Hopkins, M, Vandervoort, M K, Wong, C J, Hewitt, L, Rice, G P, Ebers, G C, Noseworthy, J H

“…Twenty-nine mildly disabled patients with multiple sclerosis underwent serial clinical and magnetic resonance imaging (MRI) evaluations (pre- and…”
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A Controlled Trial of a Critical Pathway for Treatment of Community-Acquired Pneumonia by Marrie, Thomas J, Lau, Catherine Y, Wheeler, Susan L, Wong, Cindy J, Vandervoort, Margaret K, Feagan, Brian G, for the CAPITAL Study Investigators

“…CONTEXT Large variations exist among hospitals in the use of treatment resources for community-acquired pneumonia (CAP). Lack of a common approach to the…”
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The prevalence of primary Sjögren's syndrome in a multiple sclerosis population by Noseworthy, J H, Bass, B H, Vandervoort, M K, Ebers, G C, Rice, G P, Weinshenker, B G, McLay, C J, Bell, D A

“…A central nervous system illness closely resembling multiple sclerosis has been described in patients with primary Sjögren's syndrome. From these reports, the…”
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NMR studies in experimental allergic encephalomyelitis: factors which contribute to T1 and T2 values by Karlik, S J, Gilbert, J J, Wong, C, Vandervoort, M K, Noseworthy, J H

“…To determine the factors which may alter NMR relaxation times in multiple sclerosis (MS) lesions we measured the proton T1 and T2, specific gravity (SG), and…”
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Treatment and outcomes of community-acquired pneumonia at Canadian hospitals by Feagan, B G, Marrie, T J, Lau, C Y, Wheeler, S L, Wong, C J, Vandervoort, M K

“…Community-acquired pneumonia is a common disease with a large economic burden. We assessed clinical practices and outcomes among patients with…”
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A referendum on clinical trial research in multiple sclerosis: the opinion of the participants at the Jekyll Island workshop by NOSEWORTHY, J. H, VANDERVOORT, M. K, HOPKINS, M, EBERS, G. C

“…Sixty-two experienced multiple sclerosis (MS) investigators attending a research workshop were asked their opinions about clinical trial design, outcome…”
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Plasma exchange for MS by Noseworthy, J H, Vandervoort, M K, Ebers, G C

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Postnatal NMR changes in guinea pig central nervous system: potential relevance to experimental allergic encephalomyelitis by Noseworthy, J H, Gilbert, J J, Vandervoort, M K, Karlik, S J

“…The age of sensitization determines the clinical course of experimental allergic encephalomyelitis (EAE) in the guinea pig. Adult animals immunized with…”
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Evaluation of portable bladder ultrasound: accuracy and effect on nursing practice in an acute care neuroscience unit by O'Farrell, B, Vandervoort, M K, Bisnaire, D, Doyle-Pettypiece, P, Koopman, W J, McEwan, L

“…The purpose of this evaluation was to determine the accuracy of a portable ultrasound instrument in assessing bladder volume in an acute care neuroscience…”
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Acceptance of placebo-control trial design by progressive multiple sclerosis patients by NOSEWORTHY, J. H, VANDERVOORT, M. K, EBERS, G. C

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Methotrexate in Combination With Infliximab Is No More Effective Than Infliximab Alone in Patients With Crohn's Disease by Feagan, Brian G, McDonald, John W.D, Panaccione, Remo, Enns, Robert A, Bernstein, Charles N, Ponich, Terry P, Bourdages, Raymond, MacIntosh, Donald G, Dallaire, Chrystian, Cohen, Albert, Fedorak, Richard N, Paré, Pierre, Bitton, Alain, Saibil, Fred, Anderson, Frank, Donner, Allan, Wong, Cindy J, Zou, Guangyong, Vandervoort, Margaret K, Hopkins, Marybeth, Greenberg, Gordon R

“…Background & Aims Methotrexate and infliximab are effective therapies for Crohn's disease (CD). In the combination of maintenance methotrexate-infliximab…”
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A Randomized, Double-Blind, Sham-Controlled Study of Granulocyte/Monocyte Apheresis for Active Ulcerative Colitis by Sands, Bruce E, Sandborn, William J, Feagan, Brian, Löfberg, Robert, Hibi, Toshifumi, Wang, Tao, Gustofson, Lisa–Marie, Wong, Cindy J, Vandervoort, Margaret K, Hanauer, Stephen

“…Background & Aims: Activated granulocytes and monocytes/macrophages are implicated in the pathogenesis of ulcerative colitis. Open-label studies and clinical…”
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