Search Results - "VANDENBERGHE, Peter"

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology by Vanmeerbeek, Isaure, Sprooten, Jenny, De Ruysscher, Dirk, Tejpar, Sabine, Vandenberghe, Peter, Fucikova, Jitka, Spisek, Radek, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo, Garg, Abhishek D.

“…The term 'immunogenic cell death' (ICD) denotes an immunologically unique type of regulated cell death that enables, rather than suppresses, T cell-driven…”
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Proposed refined diagnostic criteria and classification of eosinophil disorders and related syndromes by Valent, Peter, Klion, Amy D., Roufosse, Florence, Simon, Dagmar, Metzgeroth, Georgia, Leiferman, Kristin M., Schwaab, Juliana, Butterfield, Joseph H., Sperr, Wolfgang R., Sotlar, Karl, Vandenberghe, Peter, Hoermann, Gregor, Haferlach, Torsten, Moriggl, Richard, George, Tracy I., Akin, Cem, Bochner, Bruce S., Gotlib, Jason, Reiter, Andreas, Horny, Hans‐Peter, Arock, Michel, Simon, Hans‐Uwe, Gleich, Gerald J.

“…Eosinophilia and eosinophil activation are recurrent features in various reactive states and certain hematologic malignancies. In patients with…”
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Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes by Valent, Peter, MD, Klion, Amy D., MD, Horny, Hans-Peter, MD, Roufosse, Florence, MD, PhD, Gotlib, Jason, MD, Weller, Peter F., MD, Hellmann, Andrzej, MD, Metzgeroth, Georgia, MD, Leiferman, Kristin M., MD, Arock, Michel, PharmD, PhD, Butterfield, Joseph H., MD, Sperr, Wolfgang R., MD, Sotlar, Karl, MD, Vandenberghe, Peter, MD, PhD, Haferlach, Torsten, MD, Simon, Hans-Uwe, MD, PhD, Reiter, Andreas, MD, Gleich, Gerald J., MD

“…Eosinophilia is an important indicator of various neoplastic and nonneoplastic conditions. Depending on the underlying disease and mechanisms, eosinophil…”
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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes by Jansen, Joop H, Nikoloski, Gorica, Langemeijer, Saskia M C, Kuiper, Roland P, Knops, Ruth, Massop, Marion, Tönnissen, Evelyn R L T M, van der Heijden, Adrian, Scheele, Theresia N, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A

“…In myelodysplastic syndromes (MDS), deletions of chromosome 7 or 7q are common and correlate with a poor prognosis. The relevant genes on chromosome 7 are…”
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Circulating cell-free DNA in hematological malignancies by Buedts, Lieselot, Vandenberghe, Peter

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Acquired mutations in TET2 are common in myelodysplastic syndromes by Jansen, Joop H, Langemeijer, Saskia M C, Kuiper, Roland P, Berends, Marieke, Knops, Ruth, Aslanyan, Mariam G, Massop, Marion, Stevens-Linders, Ellen, van Hoogen, Patricia, van Kessel, Ad Geurts, Raymakers, Reinier A P, Kamping, Eveline J, Verhoef, Gregor E, Verburgh, Estelle, Hagemeijer, Anne, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A

“…Myelodysplastic syndromes (MDS) represent a heterogeneous group of neoplastic hematopoietic disorders. Several recurrent chromosomal aberrations have been…”
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Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia by Vicente, Carmen, Schwab, Claire, Broux, Michaël, Geerdens, Ellen, Degryse, Sandrine, Demeyer, Sofie, Lahortiga, Idoya, Elliott, Alannah, Chilton, Lucy, La Starza, Roberta, Mecucci, Cristina, Vandenberghe, Peter, Goulden, Nicholas, Vora, Ajay, Moorman, Anthony V, Soulier, Jean, Harrison, Christine J, Clappier, Emmanuelle, Cools, Jan

“…T-cell acute lymphoblastic leukemia is caused by the accumulation of multiple oncogenic lesions, including chromosomal rearrangements and mutations. To…”
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Chimeric Antigen Receptor-T-Cell Therapy for B-Cell Hematological Malignancies: An Update of the Pivotal Clinical Trial Data by Roex, Gils, Feys, Tom, Beguin, Yves, Kerre, Tessa, Poiré, Xavier, Lewalle, Philippe, Vandenberghe, Peter, Bron, Dominique, Anguille, Sébastien

“…Chimeric antigen receptor (CAR)-T-cell therapy is an innovative form of adoptive cell therapy that has revolutionized the treatment of certain hematological…”
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In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy by Marcelis, Lukas, Antoranz, Asier, Delsupehe, Anne-Marie, Biesemans, Pauline, Ferreiro, Julio Finalet, Debackere, Koen, Vandenberghe, Peter, Verhoef, Gregor, Gheysens, Olivier, Cattoretti, Giorgio, Bosisio, Francesca Maria, Sagaert, Xavier, Dierickx, Daan, Tousseyn, Thomas

“…Primary central nervous system lymphoma (PCNSL) is a rare type of non-Hodgkin lymphoma with an aggressive clinical course. To investigate the potential of…”
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Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma by Locke, Frederick L., Miklos, David B., Jacobson, Caron A., Perales, Miguel-Angel, Kersten, Marie-José, Oluwole, Olalekan O., Ghobadi, Armin, Rapoport, Aaron P., McGuirk, Joseph, Pagel, John M., Muñoz, Javier, Farooq, Umar, van Meerten, Tom, Reagan, Patrick M., Sureda, Anna, Flinn, Ian W., Vandenberghe, Peter, Song, Kevin W., Dickinson, Michael, Minnema, Monique C., Riedell, Peter A., Leslie, Lori A., Chaganti, Sridhar, Yang, Yin, Filosto, Simone, Shah, Jina, Schupp, Marco, To, Christina, Cheng, Paul, Gordon, Leo I., Westin, Jason R.

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Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology by Stanley, Kate E., Jatsenko, Tatjana, Tuveri, Stefania, Sudhakaran, Dhanya, Lannoo, Lore, Van Calsteren, Kristel, de Borre, Marie, Van Parijs, Ilse, Van Coillie, Leen, Van Den Bogaert, Kris, De Almeida Toledo, Rodrigo, Lenaerts, Liesbeth, Tejpar, Sabine, Punie, Kevin, Rengifo, Laura Y., Vandenberghe, Peter, Thienpont, Bernard, Vermeesch, Joris Robert

“…Circulating cell-free DNA (cfDNA) fragments have characteristics that are specific to the cell types that release them. Current methods for cfDNA deconvolution…”
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Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis by Skokowa, Julia, Steinemann, Doris, Katsman-Kuipers, Jenny E., Zeidler, Cornelia, Klimenkova, Olga, Klimiankou, Maksim, Ünalan, Murat, Kandabarau, Siarhei, Makaryan, Vahagn, Beekman, Renee, Behrens, Kira, Stocking, Carol, Obenauer, Julia, Schnittger, Susanne, Kohlmann, Alexander, Valkhof, Marijke G., Hoogenboezem, Remco, Göhring, Gudrun, Reinhardt, Dirk, Schlegelberger, Brigitte, Stanulla, Martin, Vandenberghe, Peter, Donadieu, Jean, Zwaan, C. Michel, Touw, Ivo P., van den Heuvel-Eibrink, Marry M., Dale, David C., Welte, Karl

“…Severe congenital neutropenia (CN) is a preleukemic bone marrow failure syndrome with a 20% risk of evolving into leukemia or myelodysplastic syndrome (MDS)…”
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Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia by Atak, Zeynep Kalender, Gianfelici, Valentina, Hulselmans, Gert, De Keersmaecker, Kim, Devasia, Arun George, Geerdens, Ellen, Mentens, Nicole, Chiaretti, Sabina, Durinck, Kaat, Uyttebroeck, Anne, Vandenberghe, Peter, Wlodarska, Iwona, Cloos, Jacqueline, Foà, Robin, Speleman, Frank, Cools, Jan, Aerts, Stein

“…RNA-seq is a promising technology to re-sequence protein coding genes for the identification of single nucleotide variants (SNV), while simultaneously…”
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Presymptomatic Identification of Cancers in Pregnant Women During Noninvasive Prenatal Testing by Amant, Frédéric, Verheecke, Magali, Wlodarska, Iwona, Dehaspe, Luc, Brady, Paul, Brison, Nathalie, Van Den Bogaert, Kris, Dierickx, Daan, Vandecaveye, Vincent, Tousseyn, Thomas, Moerman, Philippe, Vanderstichele, Adriaan, Vergote, Ignace, Neven, Patrick, Berteloot, Patrick, Putseys, Katrien, Danneels, Lode, Vandenberghe, Peter, Legius, Eric, Vermeesch, Joris Robert

“…Noninvasive prenatal testing (NIPT) for fetal aneuploidy by scanning cell-free fetal DNA in maternal plasma is rapidly becoming a major prenatal genetic test…”
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Post-transplant molecularly defined Burkitt lymphomas are frequently MYC-negative and characterized by the 11q-gain/loss pattern by Ferreiro, Julio Finalet, Morscio, Julie, Dierickx, Daan, Marcelis, Lukas, Verhoef, Gregor, Vandenberghe, Peter, Tousseyn, Thomas, Wlodarska, Iwona

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Non-invasive detection of genomic imbalances in Hodgkin/Reed-Sternberg cells in early and advanced stage Hodgkin's lymphoma by sequencing of circulating cell-free DNA: a technical proof-of-principle study by Vandenberghe, Peter, Prof, Wlodarska, Iwona, Prof, Tousseyn, Thomas, Prof, Dehaspe, Luc, PhD, Dierickx, Daan, Prof, Verheecke, Magali, MD, Uyttebroeck, Anne, Prof, Bechter, Oliver, Prof, Delforge, Michel, Prof, Vandecaveye, Vincent, Prof, Brison, Nathalie, PhD, Verhoef, Gregor EG, Prof, Legius, Eric, Prof, Amant, Frederic, Prof, Vermeesch, Joris R, Prof

“…Summary Background Hodgkin's lymphoma is one of the most common lymphoid neoplasms in young adults, but the low abundance of neoplastic Hodgkin/Reed-Sternberg…”
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Clinical, Molecular, and Prognostic Significance of WHO Type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and Various Other 3q Abnormalities in Acute Myeloid Leukemia by LUGTHART, Sanne, GRÖSCHEL, Stefan, VERHOEF, Gregor, VANDENBERGHE, Peter, FERRANT, Augustin, KÖHNE, Claus-Henning, PFREUNDSCHUH, Michael, HORST, Heinz A, KOLLER, Elisabeth, VON LILIENFELD-TOAL, Marie, BENTZ, Martin, GANSER, Arnold, BERNA BEVERLOO, H, SCHLEGELBERGER, Brigitte, JOTTERAND, Martine, KRAUTER, Jürgen, PABST, Thomas, THEOBALD, Matthias, SCHLENK, Richard F, DELWEL, Ruud, DÖHNER, Konstanze, LÖWENBERG, Bob, DÖHNER, Hartmut, KAYSER, Sabine, VALK, Peter J. M, VAN ZELDEREN-BHOLA, Shama Lydia, JAN OSSENKOPPELE, Gert, VELLENGA, Edo, VAN DEN BERG-DE RUITER, Eva, SCHANZ, Urs

“…Acute myeloid leukemia (AML) with inv(3)(q21q26.2)/t(3;3)(q21;q26.2) [inv(3)/t(3;3)] is recognized as a distinctive entity in the WHO classification. Risk…”
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A phase II study of the oral JAK1/JAK2 inhibitor ruxolitinib in advanced relapsed/refractory Hodgkin lymphoma by Van Den Neste, Eric, André, Marc, Gastinne, Thomas, Stamatoullas, Aspasia, Haioun, Corinne, Belhabri, Amine, Reman, Oumedaly, Casasnovas, Olivier, Ghesquieres, Hervé, Verhoef, Gregor, Claessen, Marie-José, Poirel, Hélène A, Copin, Marie-Christine, Dubois, Romain, Vandenberghe, Peter, Stoian, Ioanna-Andrea, Cottereau, Anne S, Bailly, Sarah, Knoops, Laurent, Morschhauser, Franck

“…JAK2 constitutive activation/overexpression is common in classical Hodgkin lymphoma, and several cytokines stimulate Hodgkin lymphoma cells by recognizing…”
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Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene by van der Krogt, Jo-Anne, Bempt, Marlies Vanden, Ferreiro, Julio Finalet, Mentens, Nicole, Jacobs, Kris, Pluys, Ursula, Doms, Kathleen, Geerdens, Ellen, Uyttebroeck, Anne, Pierre, Pascal, Michaux, Lucienne, Devos, Timothy, Vandenberghe, Peter, Tousseyn, Thomas, Cools, Jan, Wlodarska, Iwona

“…Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma is characterized by 2p23/ aberrations, including the classic t(2;5)(p23;q35)/…”
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JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma by Van Roosbroeck, Katrien, Cox, Luk, Tousseyn, Thomas, Lahortiga, Idoya, Gielen, Olga, Cauwelier, Barbara, De Paepe, Pascale, Verhoef, Gregor, Marynen, Peter, Vandenberghe, Peter, De Wolf-Peeters, Chris, Cools, Jan, Wlodarska, Iwona

“…The genetics of classical Hodgkin lymphoma (cHL) is poorly understood. The finding of a JAK2-involving t(4;9)(q21;p24) in 1 case of cHL prompted us to…”
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