Search Results - "VAN WAGONER, DAVID R."

Role of Inflammation in Atrial Fibrillation Pathophysiology and Management by Harada, Masahide, Wagoner, David R. Van, Nattel, Stanley

“…Atrial fibrillation (AF) is the most common clinically relevant arrhythmia, but the methods available for treating AF and its complications (of which the most…”
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Collagen type V, interstitial fibrosis and the substrate for atrial fibrillation by Van Wagoner, David R.

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Left Atrial Size and Function in a Canine Model of Chronic Atrial Fibrillation and Heart Failure by Goldberg, Adam, Kusunose, Kenya, Qamruddin, Salima, Rodriguez, L Leonardo, Mazgalev, Todor N, Griffin, Brian P, Van Wagoner, David R, Zhang, Youhua, Popović, Zoran B

“…Our aim was to assess how atrial fibrillation (AF) induction, chronicity, and RR interval irregularity affect left atrial (LA) function and size in the setting…”
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Hyperammonaemia‐induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress by Davuluri, Gangarao, Allawy, Allawy, Thapaliya, Samjhana, Rennison, Julie H., Singh, Dharmvir, Kumar, Avinash, Sandlers, Yana, Wagoner, David R., Flask, Chris A., Hoppel, Charles, Kasumov, Takhar, Dasarathy, Srinivasan

“…Key points Hyperammonaemia occurs in hepatic, cardiac and pulmonary diseases with increased muscle concentration of ammonia. We found that ammonia results in…”
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Oxidative Stress and Inflammation in Atrial Fibrillation: Role in Pathogenesis and Potential as a Therapeutic Target by Van Wagoner, David R

“…Atrial fibrillation (AF) is one of the most prevalent and vexing cardiovascular conditions. Available treatments for AF based on ion channel blockade are only…”
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Editorial: Functional modifications of ion channels in arrhythmogenesis by Nassal, Drew, Van Wagoner, David R., El Refaey, Mona

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Transient Receptor Potential Canonical-3 Channel―Dependent Fibroblast Regulation in Atrial Fibrillation by HARADA, Masahide, XIAOBIN LUO, YANFEN SHI, KAMIYA, Kaichiro, MUROHARA, Toyoaki, KODAMA, Itsuo, TARDIF, Jean-Claude, SCHOTTEN, Ulrich, VAN WAGONER, David R, DOBREV, Dobromir, NATTEL, Stanley, XIAO YAN QI, TADEVOSYAN, Artavazd, MAGUY, Ange, ORDOG, Balazs, LEDOUX, Jonathan, KATO, Takeshi, NAUD, Patrice, VOIGT, Niels

“…Fibroblast proliferation and differentiation are central in atrial fibrillation (AF)-promoting remodeling. Here, we investigated fibroblast regulation by…”
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Cardiac Pressure Overload Decreases ETV1 Expression in the Left Atrium, Contributing to Atrial Electrical and Structural Remodeling by Yamaguchi, Naoko, Xiao, Junhua, Narke, Deven, Shaheen, Devin, Lin, Xianming, Offerman, Erik, Khodadadi-Jamayran, Alireza, Shekhar, Akshay, Choy, Alex, Wass, Sojin Y., Van Wagoner, David R., Chung, Mina K., Park, David S.

“…Elevated intracardiac pressure attributable to heart failure induces electrical and structural remodeling in the left atrium (LA) that begets atrial myopathy…”
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Electrophysiological Remodeling in Human Atrial Fibrillation by WAGONER, DAVID R. VAN

“…Atrial fibrillation (AF) is a progressive disease characterized by cumulative electrophysiological and structural remodeling of the atria. Cellular…”
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Transcriptomic Insights into the Atrial Fibrillation Susceptibility Locus near the MYOZ1 and SYNPO2L Genes by Wass, Sojin Y, Sun, Han, Tchou, Gregory, Liu, Nana, Van Wagoner, David R, Chung, Mina K, Barnard, John, Smith, Jonathan D

“…Genome-wide association studies have identified a locus on chromosome 10q22, where many co-inherited single nucleotide polymorphisms (SNPs) are associated with…”
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Chronic vagus nerve stimulation improves autonomic control and attenuates systemic inflammation and heart failure progression in a canine high-rate pacing model by Zhang, Youhua, Popovic, Zoran B, Bibevski, Steve, Fakhry, Itaf, Sica, Domenic A, Van Wagoner, David R, Mazgalev, Todor N

“…Autonomic dysfunction, characterized by sympathetic activation and vagal withdrawal, contributes to the progression of heart failure (HF). Although the…”
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What is the impact of endothelin receptor blockade on atrial remodeling in a hypertensive model? by Van Wagoner, David R.

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Atrial fibrillation rhythm is associated with marked changes in metabolic and myofibrillar protein expression in left atrial appendage by Rennison, Julie H., Li, Ling, Lin, Cheryl R., Lovano, Beth S., Castel, Laurie, Wass, Sojin Youn, Cantlay, Catherine C., McHale, Meghan, Gillinov, A. Marc, Mehra, Reena, Willard, Belinda B., Smith, Jonathan D., Chung, Mina K., Barnard, John, Van Wagoner, David R.

“…Atrial fibrillation (AF) is strongly associated with risk of stroke and heart failure. AF promotes atrial remodeling that increases risk of stroke due to left…”
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Plasma endothelin-1 levels are increased in atrial fibrillation patients with hyperthyroidism by Mayyas, Fadia, Saadeh, Nesreen, Al-Muqbel, Kusai, Van Wagoner, David R

“…Endothelin-1 (ET-1) is a potent vasoconstrictor, mitogen and inflammatory factor that may contribute to development of atrial fibrillation (AF). Plasma ET-1…”
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Left Atrial Epicardial Adiposity and Atrial Fibrillation by Batal, Omar, Schoenhagen, Paul, Shao, Mingyuan, Ayyad, Ala Eddin, Van Wagoner, David R, Halliburton, Sandra S, Tchou, Patrick J, Chung, Mina K

“…BACKGROUND—Atrial fibrillation (AF) has been linked to inflammatory factors and obesity. Epicardial fat is a source of several inflammatory mediators related…”
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The association between eicosanoids and incident atrial fibrillation in the Framingham Heart Study by Kornej, Jelena, Qadan, Maha A., Alotaibi, Mona, Van Wagoner, David R., Watrous, Jeramie D., Trinquart, Ludovic, Preis, Sarah R., Ko, Darae, Jain, Mohit, Benjamin, Emelia J., Cheng, Susan, Lin, Honghuang

“…Chronic inflammation is a continuous low-grade activation of the systemic immune response. Whereas downstream inflammatory markers are associated with atrial…”
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Effect of Dexamethasone on Atrial Fibrillation After Cardiac Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Trial by Yared, Jean-Pierre, MD, Bakri, Mohamed H., MD, PhD, Erzurum, Serpil C., MD, Moravec, Christine S., PhD, Laskowski, Daniel M., BS, RPFT, Van Wagoner, David R., PhD, Mascha, Edward, PhD, Thornton, Julie, MS

“…Objective: The purpose of this study was to assess the effect of preoperative dexamethasone (DEX) on the occurrence of postoperative atrial fibrillation (AF)…”
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Genetic Control of Left Atrial Gene Expression Yields Insights into the Genetic Susceptibility for Atrial Fibrillation by Hsu, Jeffrey, Gore-Panter, Shamone, Tchou, Gregory, Castel, Laurie, Lovano, Beth, Moravec, Christine S, Pettersson, Gosta B, Roselli, Eric E, Gillinov, A Marc, McCurry, Kenneth R, Smedira, Nicholas G, Barnard, John, Van Wagoner, David R, Chung, Mina K, Smith, Jonathan D

“…Genome-wide association studies have identified 23 loci for atrial fibrillation (AF), but the mechanisms responsible for these associations, as well as the…”
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Right atrial blood supply and complexity of induced atrial fibrillation: What’s left? by Van Wagoner, David R.

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Inflammation as a risk factor for atrial fibrillation by AVILES, Ronnier J, MARTIN, David O, CHUNG, Mina K, APPERSON-HANSEN, Carolyn, HOUGHTALING, Penny L, RAUTAHARJU, Pentti, KRONMAL, Richard A, TRACY, Russell P, VAN WAGONER, David R, PSATY, Bruce M, LAUER, Michael S

“…The presence of systemic inflammation determined by elevations in C-reactive protein (CRP) has been associated with persistence of atrial fibrillation (AF)…”
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