Search Results - "VAN VUGT, Martine J"

Liposomal Meningococcal B Vaccination: Role of Dendritic Cell Targeting in the Development of a Protective Immune Response by ARIGITA, Carmen, BEVAART, Lisette, EVERSE, Linda A, KONING, Gerben A, HENNINK, Wim E, CROMMELIN, Daan J. A, VAN DE WINKEL, Jan G. J, VAN VUGT, Martine J, KERSTEN, Gideon F. A, JISKOOT, Wim

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

The high-affinity IgG receptor, FcγRI, plays a central role in antibody therapy of experimental melanoma by BEVAART, Lisette, JANSEN, Marco J. H, VAN VUGT, Martine J, VERBEEK, J. Sjef, VAN DE WINKEL, Jan G. J, LEUSEN, Jeanette H. W

“…We examined the role of FcγR in antibody therapy of metastatic melanoma in wild-type and different FcγR knock-out mice. Treatment of B16F10-challenged…”
Get full text

CpG-A and B oligodeoxynucleotides enhance the efficacy of antibody therapy by activating different effector cell populations by VAN OJIK, Heidi H, BEVAART, Lisette, DAHLE, Christopher E, BAKKER, Annie, JANSEN, Marco J. H, VAN VUGT, Martine J, VAN DE WINKEL, Jan G. J, WEINER, George J

“…Immunostimulatory CpG oligodeoxynucleotides (ODNs) can enhance the therapeutic effect of monoclonal antibodies (mAbs) by enhancing antibody-dependent…”
Get full text

FcR γ-Chain Is Essential for Both Surface Expression and Function of Human FcγRI (CD64) In Vivo by Vugt, Martine J. van, Heijnen, Ingmar A.F.M., Capel, Peter J.A., Park, Seung Y., Ra, Chisei, Saito, Takashi, Verbeek, Joseph S., van de Winkel, Jan G.J.

“…Most Ig receptors exist as hetero-oligomeric complexes with separate ligand binding (a) and signal transducing (β, γ, or ζ) subunits. For FcγRIIIa and Fc∊RI,…”
Get full text

CpG oligodeoxynucleotides enhance FcγRI-mediated cross presentation by dendritic cells by Bevaart, Lisette, Van Ojik, Heidi H., Sun, Amanda W., Sulahian, Timothy H., Leusen, Jeanette H. W., Weiner, George J., van de Winkel, Jan G. J., Van Vugt, Martine J.

“…Dendritic cells (DC) can trigger naive CD8+ T cell responses by their capacity to cross-present exogenous antigens via the major histocompatibility complex…”
Get full text

A drying-down technique for the spreading of mammalian meiocytes from the male and female germline by Peters, A H, Plug, A W, van Vugt, M J, de Boer, P

Get full text

The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin by Gibbins, J M, Briddon, S, Shutes, A, van Vugt, M J, van de Winkel, J G, Saito, T, Watson, S P

“…There is extensive evidence to show that phosphatidylinositol 3-kinase plays an important role in signaling by the immune family of receptors, which has…”
Get full text

Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage by Michaud, E J, van Vugt, M J, Bultman, S J, Sweet, H O, Davisson, M T, Woychik, R P

“…The agouti gene normally confers the wild-type coat color of mice. Dominant mutations at the agouti locus result in a pleiotropic syndrome that is…”
Get full text

Antigen targeting to myeloid-specific human Fc gamma RI/CD64 triggers enhanced antibody responses in transgenic mice by Heijnen, I A, van Vugt, M J, Fanger, N A, Graziano, R F, de Wit, T P, Hofhuis, F M, Guyre, P M, Capel, P J, Verbeek, J S, van de Winkel, J G

“…Besides their phagocytic effector functions, myeloid cells have an essential role as accessory cells in the induction of optimal humoral immune responses by…”
Get full text

The FcγRIa (CD64) Ligand Binding Chain Triggers Major Histocompatibility Complex Class II Antigen Presentation Independently of Its Associated FcR γ-Chain by van Vugt, Martine J., Kleijmeer, Monique J., Keler, Tibor, Zeelenberg, Ingrid, van Dijk, Marc A., Leusen, Jeanette H.W., Geuze, Hans J., van de Winkel, Jan G.J.

“…Within multi-subunit Ig receptors, the FcR γ-chain immunoreceptor tyrosine-based activation motif (ITAM) plays a crucial role in enabling antigen presentation…”
Get full text

The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma by Bevaart, Lisette, Jansen, Marco J H, van Vugt, Martine J, Verbeek, J Sjef, van de Winkel, Jan G J, Leusen, Jeanette H W

“…We examined the role of FcgammaR in antibody therapy of metastatic melanoma in wild-type and different FcgammaR knock-out mice. Treatment of B16F10-challenged…”
Get full text

A Molecular Model for the Genetic and Phenotypic Characteristics of the Mouse Lethal Yellow (Ay) Mutation by Michaud, Edward J., Bultman, Scott J., Klebig, Mitchell L., Van Vugt, Martine J., Stubbs, Lisa J., Russell, Liane B., Woychik, Richard P.

“…Lethal yellow (Ay) is a mutation at the mouse agouti locus in chromosome 2 that causes a number of dominant pleiotropic effects, including a completely yellow…”
Get full text

CpG oligodeoxynucleotides enhance Fc RI-mediated cross presentation by dendritic cells by Bevaart, L.

“…Dendritic cells (DC) can trigger naive CD8<+< T cell responses by their capacity to cross-present exogenous antigens via the major histocompatibility complex…”
Get full text

CpG oligodeoxynucleotides enhance FcgammaRI-mediated cross presentation by dendritic cells by Bevaart, Lisette, Van Ojik, Heidi H, Sun, Amanda W, Sulahian, Timothy H, Leusen, Jeanette H W, Weiner, George J, Van De Winkel, Jan G J, Van Vugt, Martine J

“…Dendritic cells (DC) can trigger naive CD8(+) T cell responses by their capacity to cross-present exogenous antigens via the major histocompatibility complex…”
Get full text

The alternatively spliced CD64 transcript Fc gamma Rlb2 does not specify a surface-expressed isoform by Van Vugt, MJ, Reefman, E, Zeelenberg, I, Boonen, G, Leusen, JHW, Van de Winkel, JGJ

“…Three highly homologous genes (A, B and C) and six transcripts have been identified for the class I human IgG receptor (CD64). The hFc gamma Rla1 isoform…”
Get full text

The alternatively spliced CD64 transcript FcγRIb2 does not specify a surface‐expressed isoform by van Vugt, Martine J., Reefman, Esther, Zeelenberg, Ingrid, Boonen, Ger, Leusen, Jeanette H. W., van de Winkel, Jan G. J.

“…Three highly homologous genes (A, B and C) and six transcripts have been identified for the class I human IgG receptor (CD64). The hFcγRIa1 isoform encodes the…”
Get full text

The p85 Subunit of Phosphatidylinositol 3-Kinase Associates with the Fc Receptor γ-Chain and Linker for Activitor of T Cells (LAT) in Platelets Stimulated by Collagen and Convulxin by Jonathan M. Gibbins, Stephen Briddon, Adam Shutes, Martine J. van Vugt, Jan G. J. van de Winkel, Takashi Saito, Stephen P. Watson

“…There is extensive evidence to show that phosphatidylinositol 3-kinase plays an important role in signaling by the immune family of receptors, which has…”
Get full text

The FcγRIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR γ-chain by VAN VUGT, M. J, KLEIJMEER, M. J, KELER, T, ZEELENBERG, I, VAN DIJK, M. A, LEUSEN, J. H. W, GEUZE, H. J, VAN DE WINKEL, J. G. J

“…Within multi-subunit Ig receptors, the FcR γ-chain immunoreceptor tyrosine-based activation motif (ITAM) plays a crucial role in enabling antigen presentation…”
Get full text

SHORT COMMUNICATIONS A drying-down technique for the spreading of mammalian meiocytes from the male and female germline by Peters, Antoine Hfm, Plug, Annemieke W, van Vugt, Martine J, de Boer, Peter

Get full text