Search Results - "VAN ROOIJEN, N."
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1
Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets
Published in The Journal of clinical investigation (01-12-2015)“…Thrombosis is a common, life-threatening consequence of systemic infection; however, the underlying mechanisms that drive the formation of infection-associated…”
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2
Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo
Published in Oncogene (17-07-2014)“…Increased expression of HBEGF in estrogen receptor-negative breast tumors is correlated with enhanced metastasis to distant organ sites and more rapid disease…”
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3
Eosinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages
Published in Journal of leukocyte biology (01-06-2007)“…Eosinophils are associated with allergic diseases and helminth infections. Development of these cells and recruitment to peripheral tissues are only partially…”
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4
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
Published in Proceedings of the National Academy of Sciences - PNAS (28-07-2009)“…Diffuse infiltration of glioma cells into normal brain tissue is considered to be a main reason for the unfavorable outcomes of patients with malignant…”
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5
Splenic Architecture and Function Requires Tight Control of Transmembrane TNF Expression
Published in International journal of molecular sciences (17-02-2022)“…Soluble tumor necrosis factor (sTNF) is an important inflammatory mediator and essential for secondary lymphoid organ (SLO) development and function. However,…”
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6
Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein
Published in The European respiratory journal (01-08-2008)“…Streptococcus pyogenes of the M1 serotype can cause streptococcal toxic shock syndrome commonly associated with acute lung injury. The aim of the present study…”
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7
Functional and phenotypic characteristics of testicular macrophages in experimental autoimmune orchitis
Published in The Journal of pathology (01-06-2008)“…Testicular inflammation with compromised fertility can occur despite the fact that the testis is considered an immunoprivileged organ. Testicular macrophages…”
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8
Tolerance to lipopolysaccharide promotes an enhanced neutrophil extracellular traps formation leading to a more efficient bacterial clearance in mice
Published in Clinical and experimental immunology (01-04-2012)“…Summary Tolerance to lipopolysaccharide (LPS) constitutes a stress adaptation, in which a primary contact with LPS results in a minimal response when a second…”
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9
Increased frequency of CD16+ monocytes and the presence of activated dendritic cells in salivary glands in primary Sjögren syndrome
Published in Annals of the rheumatic diseases (01-03-2009)“…In the salivary glands of patients with primary Sjögren Syndrome (pSjS) an accumulation of dendritic cells (DCs) is seen, which is thought to play a role in…”
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10
Exposure of Plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity
Published in Molecular and biochemical parasitology (01-11-2007)“…Malaria sporozoites migrate through several cells prior to a productive invasion that involves the formation of a parasitophorous vacuole (PV) where…”
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11
Combination therapy with hepatocyte growth factor and oseltamivir confers enhanced protection against influenza viral pneumonia
Published in Current molecular medicine (01-06-2014)“…Frequent outbreaks caused by influenza viruses pose considerable public health threats worldwide. Virus-inflicted alveolar damage represents a major…”
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12
Depletion of resident alveolar macrophages does not prevent Fas-mediated lung injury in mice
Published in American journal of physiology. Lung cellular and molecular physiology (01-08-2008)“…Activation of the Fas/Fas ligand (FasL) system in the lungs results in a form of injury characterized by alveolar epithelial apoptosis and neutrophilic…”
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13
Contribution of Type H Blood Vessels to Pathologic Osteogenesis and Inflammation in an Experimental Spondyloarthritis Model
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2023)“…Objective Spondyloarthritis (SpA) is characterized by pathologic osteogenesis, inflammation, and extensive angiogenesis in axial and peripheral tissues…”
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14
Chick embryo lethal orphan virus can be polymer-coated and retargeted to infect mammalian cells
Published in Gene therapy (01-02-2006)“…Non-human adenovirus vectors have attractive immunological properties for gene therapy but are frequently restricted by inefficient transduction of human…”
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15
Differential Contribution of NF-κB Signaling Pathways to CD4+ Memory T Cell Induced Activation of Endothelial Cells
Published in Frontiers in immunology (13-06-2022)“…Endothelial cells (ECs) are important contributors to inflammation in immune-mediated inflammatory diseases (IMIDs). In this study, we examined whether CD4 +…”
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16
Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen
Published in Blood (19-05-2011)“…Marginal zone macrophages (MZMs) are a small subset of specialized splenic macrophages known to interact with apoptotic material entering the spleen from…”
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17
Macrophage-mediated neuroprotection and neurogenesis in the olfactory epithelium
Published in Physiological genomics (14-11-2007)“…1 Department of Physiology, University of Kentucky College of Medicine 2 Department of Statistics, University of Kentucky 3 Department of Anatomy and…”
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18
Human Malaria in Immunocompromised Mice: New In Vivo Model for Chemotherapy Studies
Published in Antimicrobial Agents and Chemotherapy (01-06-2001)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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19
Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action
Published in Cell metabolism (08-09-2010)“…The contribution of interleukin (IL)-6 signaling in obesity-induced inflammation remains controversial. To specifically define the role of hepatic IL-6…”
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20
Minocycline reduces glioma expansion and invasion by attenuating microglial MT1-MMP expression
Published in Brain, behavior, and immunity (01-05-2011)“…Abstract Glioma cells release soluble factors, which induce the expression of membrane type 1 matrix metalloprotease (MT1-MMP) in tumor associated microglia…”
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