Search Results - "VAN PELT, Jos"

Pro-Inflammatory Cytokines but Not Endotoxin-Related Parameters Associate with Disease Severity in Patients with NAFLD by du Plessis, Johannie, Korf, Hannelie, van Pelt, Jos, Windmolders, Petra, Vander Elst, Ingrid, Verrijken, An, Hubens, Guy, Van Gaal, Luc, Cassiman, David, Nevens, Frederik, Francque, Sven, van der Merwe, Schalk

“…Intestinal dysbiosis and elevated lipopolysaccharides (LPS) levels have been implicated in the development of obesity, insulin resistance and non-alcoholic…”
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Is there a role for neuregulin 4 in human nonalcoholic fatty liver disease? by De Munck, Toon J I, Boesch, Markus, Verhaegh, Pauline, Masclee, Ad A M, Jonkers, Daisy, van Pelt, Jos F, du Plessis, Johannie, Korf, Hannelie, Nevens, Frederik, Koek, Ger H, Van der Merwe, Schalk, Verbeek, Jef

“…Neuregulin 4 (Nrg4), a novel adipokine enriched in brown adipose tissue has been observed to negatively regulate de novo hepatic lipogenesis and limit…”
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Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules by LIBBRECHT, Louis, SEVERI, Tamara, CASSIMAN, David, VANDER BORGHT, Sara, PIRENNE, Jacques, NEVENS, Frederik, VERSLYPE, Chris, VAN PELT, Jos, ROSKAMS, Tania

“…Distinguishing small hepatocellular carcinoma (HCC) from other types of small focal lesions that occur in a cirrhotic liver can be difficult on the basis of…”
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Stabilization of Hypoxia-Inducible Factors and BNIP3 Promoter Methylation Contribute to Acquired Sorafenib Resistance in Human Hepatocarcinoma Cells by Méndez-Blanco, Carolina, Fondevila, Flavia, Fernández-Palanca, Paula, García-Palomo, Andrés, Pelt, Jos van, Verslype, Chris, González-Gallego, Javier, Mauriz, José L

“…Despite sorafenib effectiveness against advanced hepatocarcinoma (HCC), long-term exposure to antiangiogenic drugs leads to hypoxic microenvironment, a key…”
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Tumor initiation and progression in hepatocellular carcinoma: risk factors, classification, and therapeutic targets by Severi, Tamara, van Malenstein, Hannah, Verslype, Chris, van Pelt, Jos F

“…Hepatocellular carcinoma (HCC) is a major health problem worldwide responsible for 500 000 deaths annually. A number of risk factors are associated with either…”
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Assessing warm ischemic injury of pig livers at hypothermic machine perfusion by Liu, Qiang, MD, PhD, Vekemans, Katrien, PhD, Iania, Leonardo, PhD, Komuta, Mina, MD, Parkkinen, Jaakko, PhD, Heedfeld, Veerle, Wylin, Tine, PhD, Monbaliu, Diethard, MD, PhD, Pirenne, Jacques, MD, PhD, van Pelt, Jos, PhD, Ing

“…Abstract Background Livers originating from donation after circulatory death (DCD) donors are exposed to warm ischemia (WI) before liver transplantation (LTx)…”
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Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study by Hermans, Els, Van der Merwe, Schalk W, Depreeuw, Jeroen, Dekervel, Jeroen, Radaelli, Enrico, Roskams, Tania, van Pelt Jos, Jos, Topal, Baki, Verslype, Chris, Prenen, Hans, Van Steenbergen, Werner, Nevens, Frederik, Lambrechts, Diether, Amant, Frédéric

“…Typically, pancreatic patient-derived tumor xenografts (PDXs) are established by transplanting large tumor biopsies obtained through invasive surgery…”
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Stimulation of reactive oxygen species and collagen synthesis by angiotensin II in cardiac fibroblasts by Lijnen, Paul J, van Pelt, Jos F, Fagard, Robert H

“…Superoxide anion generated by NAD(P)H-oxidase has an important role in the pathogenesis of cardiovascular diseases and scavenging superoxide anion can be…”
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Breast Cancer Resistance Protein (BCRP/ABCG2) Is Expressed by Progenitor Cells/Reactive Ductules and Hepatocytes and Its Expression Pattern Is Influenced by Disease Etiology and Species Type: Possible Functional Consequences by Vander Borght, Sara, Libbrecht, Louis, Katoonizadeh, Aezam, van Pelt, Jos, Cassiman, David, Nevens, Frederik, Van Lommel, Alfons, Petersen, Bryon E, Fevery, Johan, Jansen, Peter L, Roskams, Tania A

“…Breast cancer resistance protein (BCRP/ABCG2) is an ATP-binding cassette transport protein that is expressed in several organs including the liver. Previous…”
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Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis by Broadfield, Lindsay A, Duarte, João André Gonçalves, Schmieder, Roberta, Broekaert, Dorien, Veys, Koen, Planque, Mélanie, Vriens, Kim, Karasawa, Yasuaki, Napolitano, Francesco, Fujita, Suguru, Fujii, Masashi, Eto, Miki, Holvoet, Bryan, Vangoitsenhoven, Roman, Fernandez-Garcia, Juan, Van Elsen, Joke, Dehairs, Jonas, Zeng, Jia, Dooley, James, Rubio, Rebeca Alba, van Pelt, Jos, Grünewald, Thomas G P, Liston, Adrian, Mathieu, Chantal, Deroose, Christophe M, Swinnen, Johannes V, Lambrechts, Diether, di Bernardo, Diego, Kuroda, Shinya, De Bock, Katrien, Fendt, Sarah-Maria

“…Hepatic fat accumulation is associated with diabetes and hepatocellular carcinoma (HCC). Here, we characterize the metabolic response that high-fat…”
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Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism by Duparc, Thibaut, Plovier, Hubert, Marrachelli, Vannina G, Van Hul, Matthias, Essaghir, Ahmed, Ståhlman, Marcus, Matamoros, Sébastien, Geurts, Lucie, Pardo-Tendero, Mercedes M, Druart, Céline, Delzenne, Nathalie M, Demoulin, Jean-Baptiste, van der Merwe, Schalk W, van Pelt, Jos, Bäckhed, Fredrik, Monleon, Daniel, Everard, Amandine, Cani, Patrice D

“…To examine the role of hepatocyte myeloid differentiation primary-response gene 88 (MyD88) on glucose and lipid metabolism. To study the impact of the innate…”
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Histology obtained by needle biopsy gives additional information on the prognosis of hepatocellular carcinoma by van Malenstein, Hannah, Komuta, Mina, Verslype, Chris, Vandecaveye, Vincent, Van Calster, Ben, Topal, Baki, Laleman, Wim, Cassiman, David, Van Steenbergen, Werner, Aerts, Raymond, Vanbeckevoort, Dirk, Bielen, Didier, Pirenne, Jacques, van Pelt, Jos, Roskams, Tania, Nevens, Frederik

“…Aim:  Hepatocellular carcinomas (HCC) have a strong biological heterogeneity. Current prognostic scores do not include histology. Information on the behavior…”
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Up-regulation of breast cancer resistance protein expression in hepatoblastoma following chemotherapy: A study in patients and in vitro by Vander Borght, Sara, Van Pelt, Jos, Van Malenstein, Hannah, Cassiman, David, Renard, Marleen, Verslype, Chris, Libbrecht, Louis, Roskams, Tania A.

“…Aim:  Hepatoblastoma (HB), the most common pediatric malignant liver tumor, is treated with chemotherapy to facilitate surgical resection. Previous studies…”
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Hepatitis B virus replication causes oxidative stress in HepAD38 liver cells by Severi, Tamara, Ying, Chunxiao, Vermeesch, Joris Robert, Cassiman, David, Cnops, Lieselotte, Verslype, Chris, Fevery, Johan, Arckens, Lutgarde, Neyts, Johan, Pelt, Jos F. van

“…We used human hepatoma HepAD38 cells, in which HBV production is under the control of a tetracycline-regulated promotor, to investigate changes induced in the…”
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Protective effects of Mentha piperita L. leaf essential oil against CCl4 induced hepatic oxidative damage and renal failure in rats by Bellassoued, Khaled, Ben Hsouna, Anis, Athmouni, Khaled, van Pelt, Jos, Makni Ayadi, Fatma, Rebai, Tarek, Elfeki, Abdelfattah

“…BACKGROUNDMentha piperita L. is a flowering plant belonging to the Lamiaceae family. Mentha plants constitute one of the main valuable sources of essential oil…”
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Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality by van Pelt, Jos, Meeusen, Bob, Derua, Rita, Guffens, Liesbeth, Van Cutsem, Eric, Janssens, Veerle, Verslype, Chris

“…Pancreatic ductal adenocarcinoma (PDAC) has a low survival, its incidence is rising and little therapeutic improvements are expected in the near future. It has…”
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Correction: Méndez-Blanco et al. Stabilization of Hypoxia-Inducible Factors and BNIP3 Promoter Methylation Contribute to Acquired Sorafenib Resistance in Human Hepatocarcinoma Cells. Cancers 2019, 11 , 1984 by Méndez-Blanco, Carolina, Fondevila, Flavia, Fernández-Palanca, Paula, García-Palomo, Andrés, van Pelt, Jos, Verslype, Chris, González-Gallego, Javier, Mauriz, José L

“…In the original publication [...]…”
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Circulating AST, H-FABP, and NGAL are Early and Accurate Biomarkers of Graft Injury and Dysfunction in a Preclinical Model of Kidney Transplantation by JOCHMANS, Ina, LERUT, Evelyne, PELT, Jos Van, MONBALIU, Diethard, PIRENNE, Jacques

“…To investigate circulating biomarkers of initial graft injury in a porcine kidney autotransplant model. Injury endured by kidney grafts early posttransplant…”
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Autophagy-Related Chemoprotection against Sorafenib in Human Hepatocarcinoma: Role of FOXO3 Upregulation and Modulation by Regorafenib by Fondevila, Flavia, Méndez-Blanco, Carolina, Fernández-Palanca, Paula, Payo-Serafín, Tania, van Pelt, Jos, Verslype, Chris, González-Gallego, Javier, Mauriz, José L

“…Early acquisition of sorafenib resistance is responsible for the dismal prognosis of advanced hepatocarcinoma (HCC). Autophagy, a catabolic process involved in…”
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Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer by Bulle, Ashenafi, Dekervel, Jeroen, Deschuttere, Lise, Nittner, David, Libbrecht, Louis, Janky, Rekin's, Plaisance, Stéphane, Topal, Baki, Coosemans, An, Lambrechts, Diether, Van Cutsem, Eric, Verslype, Chris, van Pelt, Jos

“…BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease that can develop therapy resistance over time. The dense stroma in PDAC plays a…”
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