Search Results - "VAN KESTEREN, Charlotte"
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Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation
Published in Clinical pharmacokinetics (01-05-2019)“…Background Fludarabine is often used as an important drug in reduced toxicity conditioning regimens prior to hematopoietic cell transplantation (HCT). As no…”
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2
Clozapine Treatment During Pregnancy and the Postpartum Period: A Systematic Literature Review
Published in The journal of clinical psychiatry (14-12-2021)“…The objective of this systematic review was to provide a critical appraisal of the evidence related to the safety of clozapine for schizophrenia during…”
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3
Association between anti-thymocyte globulin exposure and survival outcomes in adult unrelated haemopoietic cell transplantation: a retrospective, pharmacodynamic cohort analysis
Published in The Lancet. Haematology (01-04-2017)“…Anti-thymocyte globulin (ATG) is used to prevent graft-versus-host disease (GvHD) after allogeneic haemopoietic cell transplantation (HCT). However, ATG can…”
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4
Population Pharmacokinetics of Alemtuzumab (Campath) in Pediatric Hematopoietic Cell Transplantation: Towards Individualized Dosing to Improve Outcome
Published in Clinical pharmacokinetics (01-12-2019)“…Background and Objective Alemtuzumab (Campath ® ) is used to prevent graft-versus-host disease and graft failure following pediatric allogeneic hematopoietic…”
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5
Association between anti-thymocyte globulin exposure and survival outcomes in adult unrelated haemopoietic cell transplantation: a multicentre, retrospective, pharmacodynamic cohort analysis
Published in The Lancet. Haematology (01-04-2017)“…Summary Background Anti-thymocyte globulin (ATG) is used to prevent graft-versus-host disease (GvHD) after allogeneic haemopoietic cell transplantation (HCT)…”
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Association between anti-thymocyte globulin exposure and CD4+ immune reconstitution in paediatric haemopoietic cell transplantation: a multicentre, retrospective pharmacodynamic cohort analysis
Published in The Lancet. Haematology (01-05-2015)“…Summary Background Anti-thymocyte globulin (ATG) was introduced into the conditioning regimen in haemopoietic cell transplantation (HCT) to prevent…”
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Population Pharmacokinetic Modeling of Thymoglobulin® in Children Receiving Allogeneic-Hematopoietic Cell Transplantation: Towards Improved Survival Through Individualized Dosing
Published in Clinical pharmacokinetics (01-04-2015)“…Background and Objectives To prevent graft-versus-host disease and rejection in hematopoietic cell transplantation (HCT), children receive Thymoglobulin ® , a…”
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Antithymocyte globulin: Importance of good clinical pharmacological practice
Published in Journal of allergy and clinical immunology (01-08-2016)“…Furthermore, the developed models are not validated, which is essential before deriving a new recommended dose. [...]technical issues need to be addressed…”
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9
Difference in decline in renal function due to cisplatin after a short or long hydration scheme in non–small‐cell lung cancer: A retrospective cohort study (HYCIS‐XL)
Published in Journal of clinical pharmacy and therapeutics (01-10-2020)“…What is known and objective Nephrotoxicity is a frequently occurring side effect of cisplatin, which may be reduced by applying ample hydration. The aim of…”
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10
The Influence of Body Composition on the Systemic Exposure of Paclitaxel in Esophageal Cancer Patients
Published in Pharmaceuticals (Basel, Switzerland) (09-01-2021)“…Changes in body composition are associated with chemotherapy-related toxicities and effectiveness of treatment. It is hypothesized that the pharmacokinetics…”
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11
Predictive Performance of a Busulfan Pharmacokinetic Model in Children and Young Adults
Published in Therapeutic drug monitoring (01-10-2012)“…Recently a pediatric pharmacokinetic (PK) model was developed for busulfan to explain the wide variability in PK of busulfan in children, as this variability…”
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12
Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation
Published in CPT: pharmacometrics and systems pharmacology (01-05-2020)“…Optimal fludarabine exposure has been associated with improved treatment outcome in allogeneic hematopoietic cell transplantation, suggesting potential benefit…”
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13
Development of an optimal lidocaine infusion strategy for neonatal seizures
Published in European journal of pediatrics (01-09-2006)“…Lidocaine is an effective drug for the treatment of neonatal convulsions not responding to traditional anticonvulsant therapy. However, one of the side-effects…”
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A Phase I and Pharmacokinetic Study of Ecteinascidin-743 on a Daily × 5 Schedule in Patients with Solid Malignancies
Published in Clinical cancer research (01-01-2002)“…Purpose: The purpose of this study was to ( a ) assess the feasibility of administering ecteinascidin-743 (ET-743), a novel DNA minor-groove disrupting agent…”
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Pharmacokinetics and Pharmacodynamics of the Novel Marine-derived Anticancer Agent Ecteinascidin 743 in a Phase I Dose-finding Study
Published in Clinical cancer research (01-12-2000)“…Ecteinascidin (ET) 743 is an anticancer agent derived from the Caribbean tunicate Ecteinascidia turbinata . Preclinical studies revealed activity of ET-743…”
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Patients with bariatric surgery: Urgent need for accurate registration of the contraindication to enable safe pharmacotherapy in hospital and primary care
Published in European journal of clinical pharmacology (01-02-2023)“…Purpose To enable the use of automatic clinical decision support for pharmacotherapy in patients with bariatric surgery, it is necessary to register the…”
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Excellent T-cell reconstitution and survival depend on low ATG exposure after pediatric cord blood transplantation
Published in Blood (08-12-2016)“…Successful immune reconstitution (IR) is associated with improved outcomes following pediatric cord blood transplantation (CBT). Usage and timing of…”
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Population pharmacokinetics of allopurinol in full-term neonates with perinatal asphyxia
Published in Therapeutic drug monitoring (01-06-2006)“…In newborn infants, allopurinol is being tested as a free radical scavenger to prevent brain damage caused by reperfusion and oxygenation after perinatal…”
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A Dutch Survey on Medication Adjustments after Metabolic and Bariatric Surgery: Experiences of Bariatric Surgeons, Internists, Pharmacists, and General Practitioners
Published in Obesity surgery (01-05-2024)“…Background As metabolic and bariatric surgery (MBS) can alter the pharmacokinetics of drugs, post-bariatric surgery patients may require medication adjustments…”
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Impact of Bariatric Surgery in the Short and Long Term: A Need for Time-Dependent Dosing of Drugs
Published in Obesity surgery (01-10-2023)“…Sparse information is available on pharmacokinetic changes of drugs over time after bariatric surgery. By reviewing the literature on the short- and long-term…”
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