Search Results - "VAN HEININGEN, P. N. M"

Tiagabine, a novel antiepileptic agent : lack of pharmacokinetic interaction with digoxin by SNEL, S, JANSEN, J. A, PEDERSEN, P. C, JONKMAN, J. H. G, VAN HEININGEN, P. N. M

“…To assess the possibility of any clinically relevant pharmacokinetic interactions between tiagabine, a novel antiepileptic drug, and digoxin. Potential…”
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Absorption, metabolism and excretion of a single oral dose of 14 C-repaglinide during repaglinide multiple dosing by van Heiningen, P. N. M., Hatorp, V., Kramer Nielsen, K., Hansen, K. T., van Lier, J. J., De Merbel, N. C., Oosterhuis, B., Jonkman, J. H. G.

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Absorption, metabolism and excretion of a single oral dose of 14C-repaglinide during repaglinide multiple dosing by VAN HEININGEN, P. N. M, HATORP, V, NIELSEN, K. K, HANSEN, K. T, VAN LIER, J. J, DE MERBEL, N. C. V, OOSTERHUIS, B, JONKMAN, J. H. G

“…Objective: The present study was designed to assess the disposition of ^sup 14^C-repaglinide in whole blood, plasma, urine and faeces, and to measure the total…”
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The influence of age on the pharmacokinetics of the antiepileptic agent oxcarbazepine by van Heiningen, P N, Eve, M D, Oosterhuis, B, Jonkman, J H, de Bruin, H, Hulsman, J A, Richens, A, Jensen, P K

“…The disposition of oxcarbazepine was studied in 12 young and 12 elderly healthy male and 12 young and 12 elderly healthy female volunteers, with emphasis on…”
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Absorption, metabolism and excretion of 14C-candesartan and 14C-candesartan cilexetil in healthy volunteers: Angiotensin II antagonism refined: candesartan cilexetil. A novel long-acting selective AT1 receptor blocker by VAN LIER, J. J, VAN HEININGEN, P. N. M, SUNZEL, M

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Pharmacokinetic drug interaction studies with candesartan cilexetil: Angiotensin II antagonism refined: candesartan cilexetil. A novel long-acting selective AT1 receptor blocker by JONKMAN, J. H. G, VAN LIER, J. J, VAN HEININGEN, P. N. M, LINS, R, SENNEWALD, R, HÖGEMANN, A

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Influence of the endothelium on Ca2+ dependency of angiotensin II-induced contractions of rat aortic rings by van Heiningen, P N, van Zwieten, P A

“…Endothelium-dependent relaxation has been demonstrated to be involved in the regulation of vascular tone and extracellular Ca2+ was found to play a prominent…”
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Angiotensin II-induced increase in slowly exchanging 45Ca2+ in relation to contractile responses of rat and guinea-pig aorta by VAN HEININGEN, P. N. M, BATINK, H. D, VAN ZWIETEN, P. A

“…To gain more information about sources of activator Ca2+ involved in the contraction of rat and guinea-pig aorta evoked by angiotensin II and their sensitivity…”
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Calcium dependency of the angiotensin II-induced vasoconstriction in the rat by van Heiningen, P N, Bohnenn, V A, van Zwieten, P A

“…In the present study we investigated the effect of different calcium antagonists on the constrictor effect of angiotensin II (Ang II) in two vascular…”
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Interactions between the putative calcium entry promotor Bay k 8644 and pressor responses produced by α-1 and α2-adrenocepter agonists in the pithed normotensive rat by Wilffert, B., van Heiningen, P. N. M., Mathy, M. J., de Jonge, A., Thoolen, M. J. M. c., Timmermans, P. B. M. W. M., van Zwieten, P. A.

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Lack of relationship between intrinsic activity and susceptibility of pressor responses to blockade by nifedipine among the α2 agonists B-HT 920 and B-HT 958 by Wilffert, B., van Heiningen, P. N. M., Mathy, M. J., Batink, H. D., de Jonge, A., Thoolen, M. J. M. C., Timmermans, P. B. W. M., van Zwieten, P. A.

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Interactions between the putative calcium entry promotor Bay k 8644 and pressor responses produced by α1- and α2-adrenoceptor agonists in the pithed normotensive rat by WILFERT, B, VAN HEININGEN, P. N. M, MATHY, M. J, DE JONGE, A, THOOLEN, M. J. M. C, TIMMERMANS, P. B. M. W. M, VAN ZWIETEN, P. A

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Lack of relationship between intrinsic activity and susceptibility of pressor responses to blockade by nifedipine among the 2-adrenoceptor againsts B-HT 920 and B-HT 958 by WILFFERT, B, VAN HEININGEN, P. N. M, MATHY, M. J, BATINK, H. D, DE JONGE, A, THOOLEN, M. J. M. C, TIMMERMANS, P. B. M. W. M, VAN ZWIETEN, P. A

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Differential sensitivity to calcium entry blockade of angiotensin II-induced contractions of rat and guinea-pig aorta by van Heiningen, P N, van Zwieten, P A

“…Angiotensin II-amide (A II) elicits a concentration-dependent contraction of vascular smooth muscle. This vasoconstriction proved sensitive to calcium entry…”
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