Search Results - "VAN HAM, Roeland C. H. J"
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A quantitative and dynamic model of the Arabidopsis flowering time gene regulatory network
Published in PloS one (26-02-2015)“…Various environmental signals integrate into a network of floral regulatory genes leading to the final decision on when to flower. Although a wealth of…”
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Bayesian Markov Random Field analysis for protein function prediction based on network data
Published in PloS one (24-02-2010)“…Inference of protein functions is one of the most important aims of modern biology. To fully exploit the large volumes of genomic data typically produced in…”
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Finished genome of the fungal wheat pathogen Mycosphaerella graminicola reveals dispensome structure, chromosome plasticity, and stealth pathogenesis
Published in PLoS genetics (01-06-2011)“…The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici) causes septoria tritici blotch, a disease that greatly reduces the…”
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The genomes of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also signatures of common ancestry
Published in PLoS genetics (01-11-2012)“…We sequenced and compared the genomes of the Dothideomycete fungal plant pathogens Cladosporium fulvum (Cfu) (syn. Passalora fulva) and Dothistroma septosporum…”
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Mutational robustness of gene regulatory networks
Published in PloS one (25-01-2012)“…Mutational robustness of gene regulatory networks refers to their ability to generate constant biological output upon mutations that change network structure…”
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Predicting the impact of alternative splicing on plant MADS domain protein function
Published in PloS one (25-01-2012)“…Several genome-wide studies demonstrated that alternative splicing (AS) significantly increases the transcriptome complexity in plants. However, the impact of…”
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Reductive Genome Evolution in Buchnera aphidicola
Published in Proceedings of the National Academy of Sciences - PNAS (21-01-2003)“…We have sequenced the genome of the intracellular symbiont Buchnera aphidicola from the aphid Baizongia pistacea. This strain diverged 80-150 million years ago…”
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Unsupervised protein embeddings outperform hand-crafted sequence and structure features at predicting molecular function
Published in Bioinformatics (19-04-2021)“…Abstract Motivation Protein function prediction is a difficult bioinformatics problem. Many recent methods use deep neural networks to learn complex sequence…”
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Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction
Published in PLoS computational biology (24-11-2010)“…Protein sequences encompass tertiary structures and contain information about specific molecular interactions, which in turn determine biological functions of…”
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Metric learning on expression data for gene function prediction
Published in Bioinformatics (15-02-2020)“…Abstract Motivation Co-expression of two genes across different conditions is indicative of their involvement in the same biological process. However, when…”
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The quest for orthologs: finding the corresponding gene across genomes
Published in Trends in genetics (01-11-2008)“…Orthology is a key evolutionary concept in many areas of genomic research. It provides a framework for subjects as diverse as the evolution of genomes, gene…”
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Evolution of the Leucine Gene Cluster in Buchnera aphidicola: Insights from Chromosomal Versions of the Cluster
Published in Journal of Bacteriology (01-05-2004)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
A Comparison of Global Sensitivity Analysis Methods for Explainable AI With an Application in Genomic Prediction
Published in IEEE access (2022)“…Explainable Artificial Intelligence (XAI) is an increasingly important field of research required to bring AI to the next level in real-world applications…”
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14
The Genome Sequence of Blochmannia floridanus: Comparative Analysis of Reduced Genomes
Published in Proceedings of the National Academy of Sciences - PNAS (05-08-2003)“…Bacterial symbioses are widespread among insects, probably being one of the key factors of their evolutionary success. We present the complete genome sequence…”
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Molecular Characterization of the Leucine Cluster in Buchnera sp. Strain PSY, a Primary Endosymbiont of the Aphid Pemphigus spyrothecae
Published in Applied and Environmental Microbiology (01-05-2002)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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High-resolution chromosome mapping of BACs using multi-colour FISH and pooled-BAC FISH as a backbone for sequencing tomato chromosome 6
Published in The Plant journal : for cell and molecular biology (01-11-2008)“…Within the framework of the International Solanaceae Genome Project, the genome of tomato (Solanum lycopersicum) is currently being sequenced. We follow a…”
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Homologues of potato chromosome 5 show variable collinearity in the euchromatin, but dramatic absence of sequence similarity in the pericentromeric heterochromatin
Published in BMC genomics (10-05-2015)“…In flowering plants it has been shown that de novo genome assemblies of different species and genera show a significant drop in the proportion of alignable…”
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Genome-Wide Computational Function Prediction of Arabidopsis Proteins by Integration of Multiple Data Sources
Published in Plant physiology (Bethesda) (01-01-2011)“…Although Arabidopsis (Arabidopsis thaliana) is the best studied plant species, the biological role of one-third of its proteins is still unknown. We developed…”
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The genome of the stress-tolerant wild tomato species Solanum pennellii
Published in Nature genetics (01-09-2014)“…Björn Usadel and colleagues report the genome sequence of the wild tomato species Solanum pennellii . The authors identify genes important for stress…”
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Sequencing the potato genome: outline and first results to come from the elucidation of the sequence of the world's third most important food crop
Published in American journal of potato research (2009)“…Potato is a member of the Solanaceae, a plant family that includes several other economically important species, such as tomato, eggplant, petunia, tobacco and…”
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