Search Results - "VAN GRIENSVEN, Martijn"

Gene therapy for bone healing: lessons learned and new approaches by De la Vega, RODOLFO E., ATASOY-ZEYBEK, Aysegul, PANOS, JOSEPH A., Van Griensven, Martijn, EVANS, CHRISTOPHER H., BALMAYOR, Elizabeth R.

“…Although gene therapy has its conceptual origins in the treatment of Mendelian disorders, it has potential applications in regenerative medicine, including…”
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Effect of donor age and 3D-cultivation on osteogenic differentiation capacity of adipose-derived mesenchymal stem cells by Payr, Stephan, Schuseil, Tim, Unger, Marina, Seeliger, Claudine, Tiefenboeck, Thomas, Balmayor, Elizabeth R., van Griensven, Martijn

“…Background and Purpose: Age and co-morbidities compromise healing tendencies of traumatic fractures in geriatric patients. Non-healing fractures may need…”
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A graded, porous composite of natural biopolymers and octacalcium phosphate guides osteochondral differentiation of stem cells by Amann, Elisabeth, Amirall, Amisel, Franco, Albina Ribeiro, Poh, Patrina S. P., Sola Dueñas, Francisco J., Fuentes Estévez, Gastón, Leonor, I. B., Reis, R. L., Griensven, Martijn van, Balmayor, Elizabeth Rosado

“…Lesions involving the osteochondral unit are difficult to treat. Biomimetic scaffolds are previously shown as promising alternative. Such devices often lack…”
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Platelet function in baboons and humans — A comparative study of whole blood using impedance platelet aggregometry (Multiplate®) by Ponschab, Martin, MD, van Griensven, Martijn, PhD, Heitmeier, Stefan, PhD, Laux, Volker, PhD, Schlimp, Christoph J., MD, Calatzis, Andreas, MD, Bahrami, Soheyl, PhD, Redl, Heinz, PhD, Schöchl, Herbert, MD

“…Abstract Background Platelets play a pivotal role in coagulation, inflammation and wound healing. Suitable animal models that have the potential to mimic human…”
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A chronic pressure ulcer model in the nude mouse by Wassermann, Esther, Van Griensven, Martijn, Gstaltner, Karin, Oehlinger, Wolfgang, Schrei, Karl, Redl, Heinz

“…ABSTRACT The pathophysiology of pressure ulcers is not yet fully understood. Widely used experimental models lead to pressure ulcers in the skin and the…”
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miRNAs in bone tissue correlate to bone mineral density and circulating miRNAs are gender independent in osteoporotic patients by Kelch, Sarah, Balmayor, Elizabeth R., Seeliger, Claudine, Vester, Helen, Kirschke, Jan S., van Griensven, Martijn

“…We previously demonstrated the aberrant expression of nine specific miRNAs in serum from osteoporotic patients. In the present study, we further evaluated the…”
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Hyaluronic acid facilitates chondrogenesis and matrix deposition of human adipose derived mesenchymal stem cells and human chondrocytes co-cultures by Amann, Elisabeth, Wolff, Paul, Breel, Ernst, van Griensven, Martijn, Balmayor, Elizabeth R.

“…[Display omitted] Clinical success on cartilage regeneration could be achieved by using available biomaterials and cell-based approaches. In this study, we…”
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Silk fibroin microparticles as carriers for delivery of human recombinant bone morphogenetic protein-2: in vitro and in vivo bioactivity by Bessa, Paulo César, Balmayor, Elizabeth R, Hartinger, Joachim, Zanoni, Gerald, Dopler, Daniela, Meinl, Alexandra, Banerjee, Asmita, Casal, Margarida, Redl, Heinz, Reis, Rui L, van Griensven, Martijn

“…The in vitro and in vivo efficiency of fibroin microparticles as a delivery carrier for bone morphogenetic protein-2 (BMP-2) was evaluated. BMP-2 was…”
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Optimization of Bone Scaffold Porosity Distributions by Poh, Patrina S. P., Valainis, Dvina, Bhattacharya, Kaushik, van Griensven, Martijn, Dondl, Patrick

“…Additive manufacturing (AM) is a rapidly emerging technology that has the potential to produce personalized scaffolds for tissue engineering applications with…”
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Adipose-derived mesenchymal stem cells from liposuction and resected fat are feasible sources for regenerative medicine by Schneider, Sandra, Unger, Marina, van Griensven, Martijn, Balmayor, Elizabeth R

“…The use of mesenchymal stem cells (MSCs) in research and in regenerative medicine has progressed. Bone marrow as a source has drawbacks because of subsequent…”
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Cytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases by Lepennetier, Gildas, Hracsko, Zsuzsanna, Unger, Marina, Van Griensven, Martijn, Grummel, Verena, Krumbholz, Markus, Berthele, Achim, Hemmer, Bernhard, Kowarik, Markus C

“…Cytokines play multiple roles during neuro-inflammatory processes and several cytokines have been studied in the context of specific diseases. This study…”
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A Microwell-Based Intestinal Organoid-Macrophage Co-Culture System to Study Intestinal Inflammation by Kakni, Panagiota, Truckenmüller, Roman, Habibović, Pamela, van Griensven, Martijn, Giselbrecht, Stefan

“…The mammalian intestinal epithelium contains more immune cells than any other tissue, and this is largely because of its constant exposure to pathogens…”
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Whole-body CT in haemodynamically unstable severely injured patients--a retrospective, multicentre study by Huber-Wagner, Stefan, Biberthaler, Peter, Häberle, Sandra, Wierer, Matthias, Dobritz, Martin, Rummeny, Ernst, van Griensven, Martijn, Kanz, Karl-Georg, Lefering, Rolf

“…The current common and dogmatic opinion is that whole-body computed tomography (WBCT) should not be performed in major trauma patients in shock. We aimed to…”
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Mini-bones: miniaturized bone in vitro models by Fois, Maria Gabriella, van Griensven, Martijn, Giselbrecht, Stefan, Habibović, Pamela, Truckenmüller, Roman K., Tahmasebi Birgani, Zeinab Niloofar

“…Miniaturized in vitro bone models, or ‘mini-bones’, are an emerging research tool for studying bone pathophysiology and regenerative mechanisms, and for…”
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Face masks: benefits and risks during the COVID-19 crisis by Matuschek, Christiane, Moll, Friedrich, Fangerau, Heiner, Fischer, Johannes C, Zänker, Kurt, van Griensven, Martijn, Schneider, Marion, Kindgen-Milles, Detlef, Knoefel, Wolfram Trudo, Lichtenberg, Artur, Tamaskovics, Balint, Djiepmo-Njanang, Freddy Joel, Budach, Wilfried, Corradini, Stefanie, Häussinger, Dieter, Feldt, Torsten, Jensen, Björn, Pelka, Rainer, Orth, Klaus, Peiper, Matthias, Grebe, Olaf, Maas, Kitti, Gerber, Peter Arne, Pedoto, Alessia, Bölke, Edwin, Haussmann, Jan

“…The German government has made it mandatory to wear respiratory masks covering mouth and nose (MNC) as an effective strategy to fight SARS-CoV-2 infections. In…”
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Comparative analysis of bone regeneration behavior using recombinant human BMP‐2 versus plasmid DNA of BMP‐2 by Kolk, Andreas, Boskov, Marko, Haidari, Selgai, Tischer, Thomas, van Griensven, Martijn, Bissinger, Oliver, Plank, Christian

“…Bone regeneration and the osteoinductive capacity of implants are challenging issues in clinical medicine. Currently, recombinant growth factors and nonviral…”
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The Treatment of Very Large Traumatic Bone Defects of the Tibia With a Polycaprolactone-Tricalcium Phosphate 3D-Printed Cage: A Review of Three Cases by Lodewijks, Anna, Blokhuis, Taco, van Griensven, Martijn, Poeze, Martijn

“…The need for an artificial scaffold in very large bone defects is clear, not only to limit the risk of graft harvesting but also to improve clinical success…”
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The challenge of establishing preclinical models for segmental bone defect research by Reichert, Johannes C, Saifzadeh, Siamak, Wullschleger, Martin E, Epari, Devakara R, Schütz, Michael A, Duda, Georg N, Schell, Hanna, van Griensven, Martijn, Redl, Heinz, Hutmacher, Dietmar W

“…Abstract A considerable number of international research groups as well as commercial entities work on the development of new bone grafting materials,…”
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The history and value of face masks by Matuschek, Christiane, Moll, Friedrich, Fangerau, Heiner, Fischer, Johannes C, Zänker, Kurt, van Griensven, Martijn, Schneider, Marion, Kindgen-Milles, Detlef, Knoefel, Wolfram Trudo, Lichtenberg, Artur, Tamaskovics, Bálint, Djiepmo-Njanang, Freddy Joel, Budach, Wilfried, Corradini, Stefanie, Häussinger, Dieter, Feldt, Torsten, Jensen, Björn, Pelka, Rainer, Orth, Klaus, Peiper, Matthias, Grebe, Olaf, Maas, Kitti, Bölke, Edwin, Haussmann, Jan

“…In the human population, social contacts are a key for transmission of bacteria and viruses. The use of face masks seems to be critical to prevent the…”
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Changes in the temporal distribution of in-hospital mortality in severely injured patients-An analysis of the TraumaRegister DGU by Rauf, Rauend, von Matthey, Francesca, Croenlein, Moritz, Zyskowski, Michael, van Griensven, Martijn, Biberthaler, Peter, Lefering, Rolf, Huber-Wagner, Stefan

“…The temporal distribution of trauma mortality has been classically described as a trimodal pattern with an immediate, early and late peak. In modern health…”
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