Search Results - "VAN ENDERT, P. M."

Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient by BANGA, J. P., MOORE, J. K., DUHINDAN, N., MADEC, A. M., VAN ENDERT, P. M., ORGIAZZI, J., ENDL, J.

“…SUMMARY We used a GAD65‐specific human B–T cell line cognate system in vitro to investigate the modulation of GAD65 presentation by autoantibody, assessed in a…”
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Study of Antigen-Processing Steps Reveals Preferences Explaining Differential Biological Outcomes of Two HLA-A2-Restricted Immunodominant Epitopes from Human Immunodeficiency Virus Type 1 by Cohen, W M, Bianco, A, Connan, F, Camoin, L, Dalod, M, Lauvau, G, Ferriès, E, Culmann-Penciolelli, B, van Endert, P M, Briand, J P, Choppin, J, Guillet, J G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes by HARFOUCH-HAMMOUD, E, WALK, T, OTTO, H, JUNG, G, BACH, J.-F, VAN ENDERT, P. M, CAILLAT-ZUCMAN, S

“…Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes. E…”
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Genomic Polymorphism, Recombination, and Linkage Disequilibrium in Human Major Histocompatibility Complex-Encoded Antigen-Processing Genes by van Endert, P. M., Lopez, M. T., Patel, S. D., Monaco, J. J., McDevitt, H. O.

“…Recently, two subunits of a large cytosolic protease and two putative peptide transporter proteins were found to be encoded by genes within the class II region…”
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Are there unique autoantigens triggering autoimmune diseases? by Bach, J. F., Koutouzov, S., van Endert, P. M.

“…Using three reference disease models ‐ insulin‐dependent diabetes mellitus (IDDM) as a prototype of T‐cell mediated organ‐specific autoimmune disease,…”
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Autoreactive T cell Responses in Insulin-dependent (Type 1) Diabetes Mellitus. Report of the First International Workshop for Standardization of T cell assays by Roep, Bart O, Atkinson, Mark A, van Endert, Peter M, Gottlieb, Peter A, Wilson, S.Brian, Sachs, Johnny A

“…Type 1 diabetes is thought to result from a T cell-mediated destruction of the pancreatic β-cells. Multiple and sometimes conflicting studies have identified a…”
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A viral inhibitor of peptide transporters for antigen presentation by Früh, Klaus, Ahn, Kwangseog, Djaballah, Hakim, Sempé, Pascal, van Endert, Peter M, Tampé, Robert, Peterson, Per A, Yang, Young

“…Cytotoxic T lymphocytes lyse target cells after T-cell-receptor-mediated recognition of class I major histocompatibility complex molecules presenting peptides…”
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High Affinity Presentation of an Autoantigenic Peptide in Type I Diabetes by an HLA Class II Protein Encoded in a Haplotype Protecting From Disease by Bach, Jean-Marie, Otto, Heike, Nepom, Gerald T., Jung, Günther, Cohen, Hélène, Timsit, José, Boitard, Christian, van Endert, Peter M.

“…Polymorphism of the genes coding for the human histocompatibility leukocyte antigen class II DR and DQ molecules makes the single largest genetic contribution…”
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The DAM gene family encodes a new group of tumor-specific antigens recognized by human leukocyte antigen A2-restricted cytotoxic T lymphocytes by FLEISCHHAUER, K, GATTINONI, L, DALERBA, P, LAUVAU, G, ZANARIA, E, DABOVIC, B, VAN ENDERT, P. M, BORDIGNON, C, TRAVERSARI, C

“…The DAM family of genes has a high degree of homology with MAGE, both in nucleotide sequence and in neoplastic tissue-specific expression. This study…”
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Antigen processing gene polymorphisms in HLA-DR2 multiple sclerosis by LIBLAU, R, VAN ENDERT, P. M, SANDBERG-WOLLHEIM, M, PATEL, S. D, LOPEZ, M. T, LAND, S, FUGGER, L, MCDEVITT, H. O

“…The association between multiple sclerosis (MS) and alleles of the HLA class II genes indicates that at least one MS susceptibility gene is linked to the HLA…”
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Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell‐mediated immune recognition of human melanoma cells by White, Cathrine A., Thomson, Scott A., Cooper, Leanne, van Endert, Peter M., Tampe, Robert, Coupar, Barbara, Qiu, Li, Parsons, Peter G., Moss, Denis J., Khanna, Rajiv

“…Potentiation of immunogenicity of malignant cells by gene transduction provides a unique opportunity for immune targeting of human cancers in vivo. This…”
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Discordant differentiation antigen pattern in a case of Richter's syndrome with monoclonal idiotype expression and immunoglobulin gene rearrangement by VAN ENDERT, P. M, MECHTERSHEIMER, G, MOÊLLER, P, DOÊRKEN, B, HAMMERLING, G. J, MOLDENHAUER, G

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Efficient MHC Class I-Independent Amino-Terminal Trimming of Epitope Precursor Peptides in the Endoplasmic Reticulum by Fruci, Doriana, Niedermann, Gabriele, Butler, Richard H, van Endert, Peter M

“…MHC class I ligands are produced mainly by proteasomal proteolysis, in conjunction with an unknown extent of trimming by peptidases. Trimming of precursor…”
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Inhibitory and stimulatory signaling via immunoglobulin receptors: dichotomous responses elicited in clonal B cell populations by Van Endert, P M, Moldenhauer, G

“…The paradox that cross-linking of IgM antigen receptors on B cells by native or surrogate antigen can inhibit, as well as stimulate, B cell functions has…”
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Genes regulating MHC class I processing of antigen by van Endert, Peter M

“…The principal pathway of antigen processing that is associated with MHC class I involves three main steps: cytosolic peptide generation, peptide transport into…”
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A sequential model for peptide binding and transport by the transporters associated with antigen processing by van Endert, P M, Tampé, R, Meyer, T H, Tisch, R, Bach, J F, McDevitt, H O

“…The TAP proteins translocate antigenic peptides into the endoplasmic reticulum. Investigation of the specificity of this process has been complicated by…”
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Distinct functions of the ATP binding cassettes of transporters associated with antigen processing: a mutational analysis of Walker A and B sequences by Saveanu, L, Daniel, S, van Endert, P M

“…The transporters associated with antigen processing (TAP1/TAP2) provide peptides to MHC class I molecules in the endoplasmic reticulum. Like other ATP-binding…”
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Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells by Lauvau, G, Kakimi, K, Niedermann, G, Ostankovitch, M, Yotnda, P, Firat, H, Chisari, F V, van Endert, P M

“…Antigen presentation by major histocompatibility complex (MHC) class I molecules requires peptide supply by the transporters associated with antigen processing…”
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Cytotoxic T lymphocyte epitopes of HIV-1 Nef: Generation of multiple definitive major histocompatibility complex class I ligands by proteasomes by Lucchiari-Hartz, M, van Endert, P M, Lauvau, G, Maier, R, Meyerhans, A, Mann, D, Eichmann, K, Niedermann, G

“…Although a pivotal role of proteasomes in the proteolytic generation of epitopes for major histocompatibility complex (MHC) class I presentation is undisputed,…”
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Relationship Between Peptide Selectivities of Human Transporters Associated with Antigen Processing and HLA Class I Molecules by Daniel, Soizic, Brusic, Vladimir, Caillat-Zucman, Sophie, Petrovsky, Nicolai, Harrison, Leonard, Riganelli, Daniela, Sinigaglia, Francesco, Gallazzi, Fabio, Hammer, Jurgen, van Endert, Peter M

“…Efficiency of presentation of a peptide epitope by a MHC class I molecule depends on two parameters: its binding to the MHC molecule and its generation by…”
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