Search Results - "VAN EEDEN, Stephan F"

Lung Macrophage Phenotypes and Functional Responses: Role in the Pathogenesis of COPD by Yamasaki, Kei, Eeden, Stephan F van

“…Lung macrophages (LMs) are essential immune effector cells that are pivotal in both innate and adaptive immune responses to inhaled foreign matter. They either…”
Get full text

Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures by Takiguchi, Hiroto, Yang, Chen X., Yang, Cheng Wei Tony, Sahin, Basak, Whalen, Beth A., Milne, Stephen, Akata, Kentaro, Yamasaki, Kei, Yang, Julia Shun Wei, Cheung, Chung Yan, Vander Werff, Ryan, McNagny, Kelly M., Leitao Filho, Fernando Sergio, Shaipanich, Tawimas, van Eeden, Stephan F., Obeidat, Ma’en, Leung, Janice M., Sin, Don D.

“…The classical M1/M2 polarity of macrophages may not be applicable to inflammatory lung diseases including chronic obstructive pulmonary disease (COPD) due to…”
Get full text

Changes in atherosclerotic plaques induced by inhalation of diesel exhaust by Bai, Ni, Kido, Takashi, Suzuki, Hisashi, Yang, Grace, Kavanagh, Terrance J, Kaufman, Joel D, Rosenfeld, Michael E, van Breemen, Cornelis, Eeden, Stephan F. van

“…Abstract Objective Exposure to particulate matter air pollution may be an independent risk factor for cardiovascular morbidity and mortality; however, the…”
Get full text

Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction by Tamagawa, Eiji, Bai, Ni, Morimoto, Kiyoshi, Gray, Claire, Mui, Tammy, Yatera, Kazuhiro, Zhang, Xuekui, Xing, Li, Li, Yuexin, Laher, Ismail, Sin, Don D, Man, S F Paul, van Eeden, Stephan F

“…Epidemiologic and animal studies have shown that exposure to particulate matter air pollution (PM) is a risk factor for the development of atherosclerosis…”
Get more information

Lung Macrophage Functional Properties in Chronic Obstructive Pulmonary Disease by Akata, Kentaro, van Eeden, Stephan F

“…Chronic obstructive pulmonary disease (COPD) is caused by the chronic exposure of the lungs to toxic particles and gases. These exposures initiate a persistent…”
Get full text

The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter by Miyata, Ryohei, van Eeden, Stephan F.

“…Emerging epidemiological evidence suggests that exposure to particulate matter (PM) air pollution increases the risk of cardiovascular events but the exact…”
Get full text

Contribution of Lung Macrophages to the Inflammatory Responses Induced by Exposure to Air Pollutants by Hiraiwa, Kunihiko, van Eeden, Stephan F.

“…Large population cohort studies have indicated an association between exposure to particulate matter and cardiopulmonary morbidity and mortality. The…”
Get full text

Cytokines Involved in the Systemic Inflammatory Response Induced by Exposure to Particulate Matter Air Pollutants (PM10) by van EEDEN, STEPHAN F, TAN, WAN C, SUWA, TATSUSHI, MUKAE, HIROSHI, TERASHIMA, TAKESHI, FUJII, TAKESHI, QUI, DIWEN, VINCENT, RENAUD, HOGG, JAMES C

“…Elevated levels of ambient particulate matter (PM(10)) have been associated with increased cardiopulmonary morbidity and mortality. We previously showed that…”
Get full text

Macrophages-the immune effector guardians of the lung: impact of corticosteroids on their functional responses by van Eeden, Stephan F, Akata, Kentaro

“…Lung macrophages (LMs) are key immune effector cells that protect the lung from inhaled particulate matter, noxious gases and pathogens. In Chronic Obstructive…”
Get more information

L-selectin and skin damage in systemic sclerosis by Dunne, James V, van Eeden, Stephan F, Keen, Kevin J

“…L-selectin ligands are induced on the endothelium of inflammatory sites. L-selectin expression on neutrophils and monocytes may mediate the primary adhesion of…”
Get full text

Obstructive sleep apnea severity, circulating biomarkers, and cancer risk by Hirsch Allen, A J, Kendzerska, Tetyana, Bhatti, Parveen, Jen, Rachel, Myers, Renelle, Hajipour, Mohammadreza, van Eeden, Stephan F, Ayas, Najib

“…To determine whether obstructive sleep apnea (OSA) severity and/or biomarkers of inflammation/angiogenesis are associated with incident cancer in this clinical…”
Get more information

Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment by Ishii, Hiroshi, Hayashi, Shizu, Hogg, James C, Fujii, Takeshi, Goto, Yukinobu, Sakamoto, Noriho, Mukae, Hiroshi, Vincent, Renaud, van Eeden, Stephan F

“…Studies from our laboratory have shown that human alveolar macrophages (AM) and bronchial epithelial cells (HBEC) exposed to ambient particles (PM10) in vitro…”
Get full text

Particulate matter air pollution exposure: role in the development and exacerbation of chronic obstructive pulmonary disease by Ling, Sean H, van Eeden, Stephan F

“…Due to the rapid urbanization of the world population, a better understanding of the detrimental effects of exposure to urban air pollution on chronic lung…”
Get full text

Circulating levels of cell adhesion molecules and risk of cardiovascular events in obstructive sleep apnea by Peres, Bernardo U, Hirsch Allen, A. J, Daniele, Patrick, Humphries, Karin H, Taylor, Carolyn, Laher, Ismail, Almeida, Fernanda, Jen, Rachel, Sandford, Andrew J, van Eeden, Stephan F, Ayas, Najib T

“…Background Obstructive sleep apnea (OSA) patients are at increased risk of cardiovascular disease (CVD). Cell adhesion molecules (CAM) are increased in OSA and…”
Get full text

Oxidative stress in chronic obstructive pulmonary disease: a lung and systemic process by van Eeden, Stephan F, Sin, Don D

Get full text

SYSTEMIC INFLAMMATORY RESPONSE INDUCED BY PARTICULATE MATTER AIR POLLUTION: THE IMPORTANCE OF BONE-MARROW STIMULATION by Eeden, Stephan F. van, Hogg, James C.

“…The relationship between the level of particulate air pollution (PM 10 ) and the mortality and morbidity rates from respiratory and cardiovascular diseases is…”
Get full text

The pharmacology of particulate matter air pollution-induced cardiovascular dysfunction by Bai, Ni, Khazaei, Majid, van Eeden, Stephan F, Laher, Ismail

“…Since the London fog of 1952, in which more than 4000 people were killed in 4 days, the combined efforts of scientists from several disciplines, including…”
Get full text

Particulate matter induces translocation of IL-6 from the lung to the systemic circulation by Kido, Takashi, Tamagawa, Eiji, Bai, Ni, Suda, Koichi, Yang, Huei-Hsin C, Li, Yuexin, Chiang, Gary, Yatera, Kazuhiro, Mukae, Hiroshi, Sin, Don D, Van Eeden, Stephan F

“…The biological mechanisms responsible for an association between elevated concentrations of ambient particulate matter (PM) and increased cardiovascular…”
Get full text

Adhesion molecule gene variants and plasma protein levels in patients with suspected obstructive sleep apnea by Sandford, Andrew J, Ha, Amanda, Ngan, David A, Akhabir, Loubna, Saferali, Aabida, Fox, Nurit, Hirsch Allen, A J, Warby, Simon C, van Eeden, Stephan F, Ayas, Najib T

“…Untreated obstructive sleep apnea (OSA) patients have an increased risk of cardiovascular disease (CVD). Adhesion molecules, including soluble E-selectin…”
Get full text

Particulate air pollution induces progression of atherosclerosis by Suwa, Tatsushi, Hogg, James C, Quinlan, Kevin B, Ohgami, Akira, Vincent, Renaud, van Eeden, Stephan F

“…We sought to determine the effect of exposure to air pollution particulate matter <10 μm (PM10) on the progression of atherosclerosis in rabbits. Epidemiologic…”
Get full text