Search Results - "VAN DER VELDT, A. A. M"

The genomic and transcriptomic landscape of advanced renal cell cancer for individualized treatment strategies by de Joode, K., van de Geer, W. S., van Leenders, G. J. L. H., Hamberg, P., Westgeest, H. M., Beeker, A., Oosting, S. F., van Rooijen, J. M., Beerepoot, L. V., Labots, M., Mathijssen, R. H. J., Lolkema, M. P., Cuppen, E., Sleijfer, S., van de Werken, H. J. G., van der Veldt, A. A. M.

“…Differences in the clinical course and treatment responses in individual patients with advanced renal cell carcinoma (RCC) can largely be explained by the…”
Get full text

Early discontinuation of PD-1 blockade upon achieving a complete or partial response in patients with advanced melanoma: the multicentre prospective Safe Stop trial by Mulder, E E A P, de Joode, K, Litière, S, Ten Tije, A J, Suijkerbuijk, K P M, Boers-Sonderen, M J, Hospers, G A P, de Groot, J W B, van den Eertwegh, A J M, Aarts, M J B, Piersma, D, van Rijn, R S, Kapiteijn, E, Vreugdenhil, G, van den Berkmortel, F W P J, Hoop, E Oomen-de, Franken, M G, Ryll, B, Rutkowski, P, Sleijfer, S, Haanen, J B A G, van der Veldt, A A M

“…The introduction of programmed cell death protein 1 (PD-1) blockers (i.e. nivolumab and pembrolizumab) has significantly improved the prognosis of patients…”
Get full text

CD45RA + CCR7 - CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab by Kunert, Andre, Basak, Edwin A, Hurkmans, Daan P, Balcioglu, Hayri E, Klaver, Yarne, van Brakel, Mandy, Oostvogels, Astrid A M, Lamers, Cor H J, Bins, Sander, Koolen, Stijn L W, van der Veldt, Astrid A M, Sleijfer, Stefan, Mathijssen, Ron H J, Aerts, Joachim G J V, Debets, Reno

“…Checkpoint inhibitors have become standard care of treatment for non-small cell lung cancer (NSCLC), yet only a limited fraction of patients experiences…”
Get full text

Case Report: Adequate T and B Cell Responses in a SARS-CoV-2 Infected Patient After Immune Checkpoint Inhibition by de Joode, K, Oostvogels, A A M, GeurtsvanKessel, C H, de Vries, R D, Mathijssen, R H J, Debets, R, van der Veldt, A A M

“…After the COVID-19 outbreak, non-evidence based guidelines were published to advise clinicians on the adjustment of oncological treatment during this pandemic…”
Get full text

Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment by Hurkmans, Daan P, Verhoeven, Jeroen G H P, de Leur, Kitty, Boer, Karin, Joosse, Arjen, Baan, Carla C, von der Thüsen, Jan H, van Schaik, Ron H N, Mathijssen, Ron H J, van der Veldt, Astrid A M, Hesselink, Dennis A

“…In solid organ transplant (SOT) recipients, transplant rejection during immune checkpoint inhibitor (ICI) treatment for cancer is a clinical problem…”
Get full text

Reversible cognitive disorders after sunitinib for advanced renal cell cancer in patients with preexisting arteriosclerotic leukoencephalopathy by van der Veldt, A. A. M., van den Eertwegh, A. J. M., Hoekman, K., Barkhof, F., Boven, E.

Get full text

Association between single-nucleotide polymorphisms and adverse events in nivolumab-treated non-small cell lung cancer patients by Bins, Sander, Basak, Edwin A., el Bouazzaoui, Samira, Koolen, Stijn L. W., Oomen – de Hoop, E., van der Leest, Cor H., van der Veldt, Astrid A. M., Sleijfer, Stefan, Debets, Reno, van Schaik, Ron H. N., Aerts, Joachim G. J. V., Mathijssen, Ron H. J.

“…Background Treatment with PD-1 inhibitors can be hampered by severe auto-immune-related toxicities. Our objective was to identify single-nucleotide…”
Get full text

Evaluation of the tolerability and safety of [ 225 Ac]Ac-PSMA-I&T in patients with metastatic prostate cancer: a phase I dose escalation study by Ling, Sui Wai, van der Veldt, Astrid A M, Konijnenberg, Mark, Segbers, Marcel, Hooijman, Eline, Bruchertseifer, Frank, Morgenstern, Alfred, de Blois, Erik, Brabander, Tessa

“…Life expectancy of patients with metastatic castration-resistant prostate cancer (mCRPC) is still limited despite several systemic treatments. Within five…”
Get full text

Development of [11C]erlotinib Positron Emission Tomography for In Vivo Evaluation of EGF Receptor Mutational Status by BAHCE, Idris, SMIT, Egbert F, LAMMERTSMA, Adriaan A, HARRY HENDRIKSE, N, LUBBERINK, Mark, VAN DER VELDT, Astrid A. M, YAQUB, Maqsood, WINDHORST, Albert D, SCHUIT, Robert C, THUNNISSEN, Erik, HEIDEMAN, Daniëlle A. M, POSTMUS, Pieter E

“…To evaluate whether, in patients with non-small cell lung carcinoma (NSCLC), tumor uptake of [(11)C]erlotinib can be quantified and imaged using positron…”
Get full text

Oncological healthcare providers' perspectives on appropriate melanoma survivorship care: a qualitative focus group study by Kamminga, Nadia C W, Wakkee, Marlies, De Bruin, Rianne J, van der Veldt, Astrid A M, Joosse, Arjen, Reeder, Suzan W I, Plaisier, Peter W, Nijsten, Tamar, Lugtenberg, Marjolein

“…The increasing group of melanoma survivors reports multiple unmet needs regarding survivorship care (SSC). To optimise melanoma SSC, it is crucial to take into…”
Get full text

Granzyme B is correlated with clinical outcome after PD-1 blockade in patients with stage IV non-small-cell lung cancer by Hurkmans, Daan P., Basak, Edwin A., Schepers, Nina, Oomen-De Hoop, Esther, Van der Leest, Cor H., El Bouazzaoui, Samira, Bins, Sander, Koolen, Stijn L. W., Sleijfer, Stefan, Van der Veldt, Astrid A. M., Debets, Reno, Van Schaik, Ron H. N., Aerts, Joachim G. J. V., Mathijssen, Ron H. J.

“…BackgroundA minority of patients with advanced non-small-cell lung cancer (NSCLC) benefit from treatment with immune checkpoint inhibitors (ICIs). Ineffective…”
Get full text

Adverse Events in Anti-PD-1-Treated Adjuvant and First-Line Advanced Melanoma Patients by Rauwerdink, Daan Jan Willem, Not, Olivier van, de Meza, Melissa, Doorn, Remco van, Hage, Jos van der, Eertwegh, A J M van den, Haanen, John B, Aarts, Maureen J B, Berkmortel, Franchette W P J van den, Blank, Christiaan U, Boers-Sonderen, Marye J, Groot, Jan Willem B de, Hospers, Geke A P, Piersma, Djura, van Rijn, Rozemarijn S, Stevense-den Boer, A M, Veldt, Astrid A M van der, Vreugdenhil, Gerard, Wouters, Michel W J M, Suijkerbuijk, Karijn P M, Kapiteijn, Ellen

“…: The difference in incidence and severity of anti-PD-1 therapy-related adverse events (irAEs) between adjuvant and advanced treated melanoma patients remains…”
Get full text

Impact of Novel Treatments in Patients with Melanoma Brain Metastasis: Real-World Data by Derks, Sophie H A E, Jongen, Joost L M, van der Meer, Edgar L, Ho, Li Shen, Slagter, Cleo, Joosse, Arjen, de Jonge, Maja J A, Schouten, Joost W, Oomen-de Hoop, Esther, van den Bent, Martin J, van der Veldt, Astrid A M

“…Melanoma brain metastasis (MBM) is associated with poor outcome, but targeted therapies (TTs) and immune checkpoint inhibitors (ICIs) have revolutionized…”
Get full text

mRNA-1273 COVID-19 vaccination in patients receiving chemotherapy, immunotherapy, or chemoimmunotherapy for solid tumours: a prospective, multicentre, non-inferiority trial by Oosting, Sjoukje F, van der Veldt, Astrid A M, GeurtsvanKessel, Corine H, Fehrmann, Rudolf S N, van Binnendijk, Rob S, Dingemans, Anne-Marie C, Smit, Egbert F, Hiltermann, T Jeroen N, den Hartog, Gerco, Jalving, Mathilda, Westphal, Tatjana T, Bhattacharya, Arkajyoti, van der Heiden, Marieke, Rimmelzwaan, Guus F, Kvistborg, Pia, Blank, Christian U, Koopmans, Marion P G, Huckriede, Anke L W, van Els, Cecile A C M, Rots, Nynke Y, van Baarle, Debbie, Haanen, John B A G, de Vries, Elisabeth G E

“…Patients with cancer have an increased risk of complications from SARS-CoV-2 infection. Vaccination to prevent COVID-19 is recommended, but data on the…”
Get full text

Improved postprocessing of dynamic glucose-enhanced CEST MRI for imaging brain metastases at 3 T by Wu, Yulun, Derks, Sophie H. A. E., Wood, Tobias C., de Blois, Erik, van der Veldt, Astrid A. M., Smits, Marion, Warnert, Esther A. H.

“…Background Dynamic glucose-enhanced (DGE) chemical exchange saturation transfer (CEST) has the potential to characterize glucose metabolism in brain…”
Get full text

An unusual cause of hematemesis： Goiter by van der Veldt, Astrid A M, Hadithi, Mohammed, Paul, Marinus A, van den Berg, Fred G, Mulder, Chris J J, Craanen, Mikael E

“…Downhill varices are located in the upper part of the esophagus and are usually related to superior vena cava obstruction. Bleeding from these varices is…”
Get full text

Alternative dosing strategies for immune checkpoint inhibitors to improve cost-effectiveness: a special focus on nivolumab and pembrolizumab by Malmberg, Ruben, Zietse, Michiel, Dumoulin, Daphne W, Hendrikx, Jeroen J M A, Aerts, Joachim G J V, van der Veldt, Astrid A M, Koch, Birgit C P, Sleijfer, Stefan, van Leeuwen, Roelof W F

“…Immune checkpoint inhibitors have revolutionised cancer treatment by offering durable responses to many patients with solid and haematological cancers. The…”
Get full text

Lesion detection by [89Zr]Zr-DFO-girentuximab and [18F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma by Verhoeff, Sarah R., van Es, Suzanne C., Boon, Eline, van Helden, Erik, Angus, Lindsay, Elias, Sjoerd G., Oosting, Sjoukje F., Aarntzen, Erik H., Brouwers, Adrienne H., Kwee, Thomas C., Heskamp, Sandra, Hoekstra, Otto S., Verheul, Henk, van der Veldt, Astrid A. M., de Vries, Elisabeth G. E., Boerman, Otto C., van der Graaf, Winette T. A., Oyen, Wim J. G., van Herpen, Carla M. L.

“…Purpose The main objective of this preliminary analysis of the IMaging PAtients for Cancer drug selecTion (IMPACT)-renal cell cancer (RCC) study is to evaluate…”
Get full text

Experiences of resuming life after immunotherapy and associated survivorship care needs: a qualitative study among patients with metastatic melanoma by Kamminga, Nadia C.W., Veldt, Astrid A.M., Joosen, Margot C.W., Joode, Karlijn, Joosse, Arjen, Grünhagen, Dirk J., Nijsten, Tamar E.C., Wakkee, Marlies, Lugtenberg, Marjolein

“…Background Immune checkpoint inhibitors (ICIs) have significantly improved the overall survival of patients with metastatic melanoma. It is unclear how the…”
Get full text

Development and validation of a novel model to predict recurrence-free survival and melanoma-specific survival after sentinel lymph node biopsy in patients with melanoma: an international, retrospective, multicentre analysis by Stassen, Robert C, Maas, Carolien C H M, van der Veldt, Astrid A M, Lo, Serigne N, Saw, Robyn P M, Varey, Alexander H R, Scolyer, Richard A, Long, Georgina V, Thompson, John F, Rutkowski, Piotr, Keilholz, Ulrich, van Akkooi, Alexander C J, Verhoef, Cornelis, van Klaveren, David, Grünhagen, Dirk J

“…The introduction of adjuvant systemic treatment for patients with high-risk melanomas necessitates accurate staging of disease. However, inconsistencies in…”
Get full text