Search Results - "VAN DER DOES, Chris"
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Motile ghosts of the halophilic archaeon, Haloferax volcanii
Published in Proceedings of the National Academy of Sciences - PNAS (27-10-2020)“…Archaea swim using the archaellum (archaeal flagellum), a reversible rotary motor consisting of a torque-generating motor and a helical filament, which acts as…”
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Archaeal flagellar ATPase motor shows ATP-dependent hexameric assembly and activity stimulation by specific lipid binding
Published in Biochemical journal (01-07-2011)“…Microbial motility frequently depends on flagella or type IV pili. Using recently developed archaeal genetic tools, archaeal flagella and its assembly…”
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The archaeal Ced system imports DNA
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-2016)“…The intercellular transfer of DNA is a phenomenon that occurs in all domains of life and is a major driving force of evolution. Upon UV-light treatment, cells…”
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The use of thermostable fluorescent proteins for live imaging in Sulfolobus acidocaldarius
Published in Frontiers in microbiology (09-09-2024)“…Among hyperthermophilic organisms, protein localization is challenging due to the high growth temperatures that can disrupt proper folding and function of…”
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Effect of UV irradiation on Sulfolobus acidocaldarius and involvement of the general transcription factor TFB3 in the early UV response
Published in Nucleic acids research (21-08-2018)“…Abstract Exposure to UV light can result in severe DNA damage. The alternative general transcription factor (GTF) TFB3 has been proposed to play a key role in…”
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SaUspA, the Universal Stress Protein of Sulfolobus acidocaldarius Stimulates the Activity of the PP2A Phosphatase and Is Involved in Growth at High Salinity
Published in Frontiers in microbiology (13-11-2020)“…In Sulfolobus acidocaldarius , the protein phosphatase PP2A plays important regulatory roles in many cellular processes, including cell growth, cell shape and…”
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Kinetics of the ATP Hydrolysis Cycle of the Nucleotide-binding Domain of Mdl1 Studied by a Novel Site-specific Labeling Technique
Published in The Journal of biological chemistry (03-03-2006)“…We have recently proposed a “processive clamp” model for the ATP hydrolysis cycle of the nucleotide-binding domain (NBD) of the mitochondrial ABC transporter…”
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Conjugative plasmids of Neisseria gonorrhoeae
Published in PloS one (01-04-2010)“…Many clinical isolates of the human pathogen Neisseria gonorrhoeae contain conjugative plasmids. The host range of these plasmids is limited to Neisseria…”
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Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis
Published in mBio (19-12-2023)“…GPN-loop GTPases have been found to be crucial for eukaryotic RNA polymerase II assembly and nuclear trafficking. Despite their ubiquitous occurrence in…”
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PomZ, a ParA‐like protein, regulates Z‐ring formation and cell division in Myxococcus xanthus
Published in Molecular microbiology (01-01-2013)“…Summary Accurate positioning of the division site is essential to generate appropriately sized daughter cells with the correct chromosome number. In bacteria,…”
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Analysis of Cell-Cell Bridges in Haloferax volcanii Using Electron Cryo-Tomography Reveal a Continuous Cytoplasm and S-Layer
Published in Frontiers in microbiology (13-01-2021)“…Halophilic archaea have been proposed to exchange DNA and proteins using a fusion-based mating mechanism. Scanning electron microscopy previously suggested…”
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DNA processing by the MOBH family relaxase TraI encoded within the gonococcal genetic island
Published in Nucleic acids research (05-09-2019)“…Abstract Relaxases of the MOBH family are often found on large plasmids, genetic islands and integrative conjugative elements. Many members of this family…”
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Two Small GTPases Act in Concert with the Bactofilin Cytoskeleton to Regulate Dynamic Bacterial Cell Polarity
Published in Developmental cell (29-04-2013)“…Cell polarity is essential for many bacterial activities, but the mechanisms responsible for its establishment are poorly understood. In Myxococcus xanthus,…”
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Putative nucleotide-based second messengers in archaea
Published in microLife (2023)“…Abstract Second messengers transfer signals from changing intra- and extracellular conditions to a cellular response. Over the last few decades, several…”
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The nucleotide‐dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor
Published in Molecular microbiology (01-02-2016)“…Summary The motor of the membrane‐anchored archaeal motility structure, the archaellum, contains FlaX, FlaI and FlaH. FlaX forms a 30 nm ring structure that…”
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Peptidoglycan-binding protein TsaP functions in surface assembly of type IV pili
Published in Proceedings of the National Academy of Sciences - PNAS (11-03-2014)“…Type IV pili (T4P) are ubiquitous and versatile bacterial cell surface structures involved in adhesion to host cells, biofilm formation, motility, and DNA…”
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Corrigendum: The Phosphatase PP2A Interacts With ArnA and ArnB to Regulate the Oligomeric State and the Stability of the ArnA/B Complex
Published in Frontiers in microbiology (30-10-2020)Get full text
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The Phosphatase PP2A Interacts With ArnA and ArnB to Regulate the Oligomeric State and the Stability of the ArnA/B Complex
Published in Frontiers in microbiology (21-08-2020)“…In the crenarchaeon Sulfolobus acidocaldarius , the archaellum, a type-IV pilus like motility structure, is synthesized in response to nutrient starvation…”
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Characterization of the ATPase FlaI of the motor complex of the Pyrococcus furiosus archaellum and its interactions between the ATP-binding protein FlaH
Published in PeerJ (San Francisco, CA) (18-06-2018)“…The archaellum, the rotating motility structure of archaea, is best studied in the crenarchaeon . To better understand how assembly and rotation of this…”
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Functional analysis of the Gonococcal Genetic Island of Neisseria gonorrhoeae
Published in PloS one (23-10-2014)“…Neisseria gonorrhoeae is an obligate human pathogen that is responsible for the sexually-transmitted disease gonorrhea. N. gonorrhoeae encodes a T4SS within…”
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