Search Results - "VAN BOOM, J. H."
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Synthesis of Potent Agonists of the d-myo-Inositol 1,4,5-Trisphosphate Receptor Based on Clustered Disaccharide Polyphosphate Analogues of Adenophostin A
Published in Journal of medicinal chemistry (24-08-2000)“…Clustered disaccharide analogues of adenophostin A (2), i.e. mono-, di-, and tetravalent derivatives 6-8, respectively, were synthesized and evaluated as novel…”
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One-Pot Two-Step Enzymatic Coupling of Pyrimidine Bases to 2-Deoxy-d-ribose-5-phosphate. A New Strategy in the Synthesis of Stable Isotope Labeled Deoxynucleosides
Published in Journal of organic chemistry (08-03-2002)“…The enzymatic synthesis of thymidine from 2-deoxy-d-ribose-5-phosphate is achieved, in a one-pot two-step reaction using phosphoribomutase (PRM) and…”
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3
Identification of an RNA Hairpin in Poliovirus RNA That Serves as the Primary Template in the In Vitro Uridylylation of VPg
Published in Journal of Virology (01-11-2000)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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4
Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid
Published in Nature (London) (15-01-1987)“…Cellulose is the most abundant renewable carbon resource on earth and is an indispensable raw material for the wood, paper, and textile industries. A model…”
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5
Protein-primed RNA synthesis by purified poliovirus RNA polymerase
Published in Nature (London) (21-05-1998)“…A small protein, VPg, is covalently linked to the 5′ end of the plus-stranded poliovirus genomic RNA. Poliovirus messenger RNA, identical in nucleotide…”
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6
Solution structure of a DNA duplex with a chiral alkyl phosphonate moiety
Published in Nucleic acids research (15-07-2001)“…The solution structures of two DNA decamers of sequence d(CCACCpxGGAAC).(GTTCCGGTGG) with a chiral alkyl phosphonate moiety (px) have been determined using NMR…”
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7
Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics
Published in Journal of molecular biology (20-11-1993)“…The structure of the complex of lac repressor headpiece and an 11 base-pair lac half-operator has been determined by NMR spectroscopy and restrained Molecular…”
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8
Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylation
Published in Journal of virology (01-11-2000)“…In addition to highly conserved stem-loop structures located in the 5'- and 3'-nontranslated regions, genome replication of picornaviruses requires cis-acting…”
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9
Secondary chemical shifts in immobilized peptides and proteins: a qualitative basis for structure refinement under magic angle spinning
Published in Journal of biomolecular NMR (01-08-2001)“…Resonance assignments recently obtained on immobilized polypeptides and a membrane protein aggregate under Magic Angle Spinning are compared to random coil…”
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10
Revised interpretation of the immunological results obtained with pneumococcal polysaccharide 17F derived synthetic di-, tri- and tetrasaccharide conjugates in mice and rabbits
Published in Vaccine (12-10-2001)“…Recently, the structure for pneumococcal polysaccharide (PS) 17F has been revised. Based on the former PS structure, immunogenicities of PS 17F derived…”
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11
Structural Features of the DNA Hairpin d(ATCCTA-GTTA-TAGGAT): Formation of a G-A Base Pair in the Loop
Published in Nucleic acids research (15-04-1997)“…The three-dimensional structure of the hairpin formed by d(ATCCTA-GTTA-TAGGAT) has been determined by means of two-dimensional NMR studies, distance geometry…”
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12
Site-Specific Cleavage of RNA by Fe(II)·Bleomycin
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1990)“…Bleomycin is an antitumor agent whose activity has long been thought to derive from its ability to degrade DNA. Recent findings suggest that cellular RNA may…”
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13
Optimization of the binding properties of PNA-(5′)-DNA chimerae
Published in Bioorganic & medicinal chemistry letters (17-03-1998)“…The synthesis and evaluation of PNA-(5′)-DNA chimerae containing either a 5′-amide ( i.e. 1a), a 5′-phosphodiester ( i.e. 1b) or 5′-phosphonate linkages ( i.e…”
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14
Backbone and Side Chain Dynamics of lac Repressor Headpiece (1−56) and Its Complex with DNA
Published in Biochemistry (Easton) (07-01-1997)“…The dynamics of the backbone and (some of) the side chains of lac headpiece (1−56; lac HP56) have been studied for the free protein and for its complex with…”
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15
Chiral selection in poly(C)-directed synthesis of oligo(G)
Published in Nature (London) (16-08-1984)“…An experimental study is reported which shows that poly(C)-directed oligomerization of activated guanosine mononucleotides proceeds readily if the monomers are…”
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Novel hepatotrophic prodrugs of the antiviral nucleoside 9‐(2‐phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity
Published in The FASEB journal (01-09-2000)“…The device of new hepatotrophic prodrugs of the antiviral nucleoside 9‐(2‐phosphonylme‐thoxyethyl)adenine (PMEA) with specificity for the asialoglycoprotein…”
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Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys
Published in Infection and Immunity (01-05-1992)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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18
Unstable Hoogsteen Base Pairs Adjacent to Echinomycin Binding Sites within a DNA Duplex
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1989)“…The bisintercalation complex present between the DNA octamer [d(ACGTACGT)]2and the cyclic octadepsipeptide antibiotic echinomycin has been studied by one- and…”
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19
Structure determination of a DNA octamer in solution by NMR spectroscopy. Effect of fast local motions
Published in Biochemistry (Easton) (16-04-1991)“…NMR structures of biomolecules are primarily based on nuclear Overhauser effects (NOEs) between protons. For the interpretation of NOEs in terms of distances,…”
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20
Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis
Published in Biochemical journal (15-04-1995)“…Lysophosphatidic acid (LPA; 1-acyl-sn-glycero-3-phosphate) is a platelet-derived lipid mediator that activates its own G-protein-coupled receptor to trigger…”
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