Search Results - "VAN BEIJSTERVELDT, L"

Longitudinal telomere length and body composition in healthy term-born infants during the first two years of life by de Fluiter, Kirsten S, Codd, Veryan, Denniff, Matthew, Kerkhof, Gerthe F, van Beijsterveldt, Inge A L P, Breij, Laura M, Samani, Nilesh J, Abrahamse-Berkeveld, Marieke, Hokken-Koelega, Anita C S

“…Leukocyte telomere length (LTL) is one of the markers of biological aging as shortening occurs over time. Shorter LTL has been associated with adiposity and a…”
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Phase I and pharmacological study of the broad-spectrum tyrosine kinase inhibitor JNJ-26483327 in patients with advanced solid tumours by Konings, I R H M, de Jonge, M J A, Burger, H, van der Gaast, A, van Beijsterveldt, L E C, Winkler, H, Verweij, J, Yuan, Z, Hellemans, P, Eskens, F A L M

“…Background: JNJ-26483327 is an oral, potent, multi-targeted tyrosine kinase inhibitor, inhibiting kinases of epidermal growth factor receptor (EGFR)-1, -2 and…”
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The Metabolism and Excretion of Galantamine in Rats, Dogs, and Humans by MANNENS, G. S. J, SNEL, C. A. W, VAN PEER, A, MEULDERMANS, W, HENDRICKX, J, VERHAEGHE, T, LE JEUNE, L, BODE, W, VAN BEIJSTERVELDT, L, LAVRIJSEN, K, LEEMPOELS, J, VAN OSSELAER, N

“…Galantamine is a competitive acetylcholine esterase inhibitor with a beneficial therapeutic effect in patients with Alzheimer's disease. The metabolism and…”
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Association Between Fat Mass in Early Life and Later Fat Mass Trajectories by de Fluiter, Kirsten S, van Beijsterveldt, Inge A L P, Breij, Laura M, Acton, Dennis, Hokken-Koelega, Anita C S

“…A rapid increase in weight in early life is associated with an increased risk for adiposity and cardiovascular diseases at age 21 years and beyond. However,…”
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Anthropometry‐based prediction of body composition in early infancy compared to air‐displacement plethysmography by Olga, Laurentya, Beijsterveldt, Inge A. L. P., Hughes, Ieuan A., Dunger, David B., Ong, Ken K., Hokken‐Koelega, Anita C. S., De Lucia Rolfe, Emanuella

“…Summary Background Anthropometry‐based equations are commonly used to estimate infant body composition. However, existing equations were designed for newborns…”
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Intestinal uptake and biodistribution of novel polymeric micelles after oral administration by Mathot, Frédéric, van Beijsterveldt, L., Préat, V., Brewster, M., Ariën, A.

“…To determine the fate of polymeric micelles after oral administration, we investigated the possible transport of polymeric micelles across Caco-2 monolayers…”
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Prenatal and Neonatal Characteristics of Children with Prader-Willi Syndrome by Grootjen, Lionne N, Uyl, Nathalie E M, van Beijsterveldt, Inge A L P, Damen, Layla, Kerkhof, Gerthe F, Hokken-Koelega, Anita C S

“…Prader-Willi syndrome (PWS) is a rare genetic syndrome with a wide spectrum of clinical features in early life. Late diagnoses are still present. We…”
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Body Composition Assessment by Air-Displacement Plethysmography Compared to Dual-Energy X-ray Absorptiometry in Full-Term and Preterm Aged Three to Five Years by van Beijsterveldt, Inge A L P, Beunders, Victoria A A, Bijlsma, Alja, Vermeulen, Marijn J, Joosten, Koen F M, Hokken-Koelega, Anita C S

“…It is important to monitor body composition longitudinally, especially in children with atypical body composition trajectories. Dual-energy X-ray…”
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Appetite-regulating hormone trajectories and relationships with fat mass development in term-born infants during the first 6 months of life by de Fluiter, Kirsten S., Kerkhof, Gerthe F., van Beijsterveldt, Inge A. L. P., Breij, Laura M., van Vark-van der Zee, Leonie C., Mulder, Monique T., Abrahamse-Berkeveld, Marieke, Hokken-Koelega, Anita C. S.

“…Background The first 6 months of life are a critical window for adiposity programming. Appetite-regulating hormones (ARH) are involved in food intake…”
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Strategies for absorption screening in drug discovery and development by Bohets, H, Annaert, P, Mannens, G, Van Beijsterveldt, L, Anciaux, K, Verboven, P, Meuldermans, W, Lavrijsen, K

“…This review gives an overview of the current approaches to evaluate drug absorption potential in the different phases of drug discovery and development…”
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Pharmacokinetic–pharmacodynamic modelling of fluvoxamine 5‐HT transporter occupancy in rat frontal cortex by Geldof, M, Freijer, J I, Van Beijsterveldt, L, Langlois, X, Danhof, M

“…Background and purpose: The pharmacokinetic–pharmacodynamic (PK–PD) correlation of fluvoxamine 5‐HT transporter (SERT) occupancy was determined in rat frontal…”
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Fat mass and fat‐free mass track from infancy to childhood: New insights in body composition programming in early life by Beijsterveldt, Inge A. L. P., Fluiter, Kirsten S., Breij, Laura M., Steen, Manouk, Hokken‐Koelega, Anita C. S.

“…Objective Early life is a critical window for adiposity programming. This study investigated whether fat mass percentage (FM%), fat mass index (FMI), abdominal…”
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Poly- and perfluoroalkyl substances (PFAS) exposure through infant feeding in early life by van Beijsterveldt, Inge A.L.P., van Zelst, Bertrand D., de Fluiter, Kirsten S., van den Berg, Sjoerd A.A., van der Steen, Manouk, Hokken-Koelega, Anita C.S.

“…[Display omitted] •Human milk contains measurable amounts of PFOA and PFOS.•Daily PFAS intake is highest in exclusively breastfed infants of older…”
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Early life poly- and perfluoroalkyl substance levels and adiposity in the first 2 years of life by van Beijsterveldt, Inge A L P, van Zelst, Bertrand D, Dorrepaal, Demi J, van den Berg, Sjoerd A A, Hokken-Koelega, Anita C S

“…Poly- and perfluoroalkyl substances (PFASs) are nondegradable, man-made chemicals. They accumulate in humans with potential harmful effects, especially in…”
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Longitudinal poly- and perfluoroalkyl substances (PFAS) levels in Dutch infants by van Beijsterveldt, Inge A.L.P., van Zelst, Bertrand D., van den Berg, Sjoerd A.A., de Fluiter, Kirsten S., van der Steen, Manouk, Hokken-Koelega, Anita C.S.

“…[Display omitted] •PFAS levels in infants at age 3 months predict levels at age 2 years.•2–3 fold higher levels in exclusive breastfed compared to formula fed…”
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Body composition and bone mineral density by Dual Energy X-ray Absorptiometry: Reference values for young children by van Beijsterveldt, Inge A.L.P., van der Steen, Manouk, de Fluiter, Kirsten S., Spaans, Sander A.M.J., Hokken-Koelega, Anita C.S.

“…Childhood obesity is a global public health threat, with an alarming rise in incidence. Obesity at young age has short-term and long-term morbidity. It is,…”
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Longitudinal human milk macronutrients, body composition and infant appetite during early life by de Fluiter, Kirsten S., Kerkhof, Gerthe F., van Beijsterveldt, Inge A.L.P., Breij, Laura M., van de Heijning, Bert J.M., Abrahamse-Berkeveld, Marieke, Hokken-Koelega, Anita C.S.

“…Breastfeeding is the gold standard infant feeding. Data on macronutrients in relation to longitudinal body composition and appetite are very scarce. The aim of…”
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Skinfold-based-equations to assess longitudinal body composition in children from birth to age 5 years by van Beijsterveldt, Inge A.L.P., Dorrepaal, Demi J., de Fluiter, Kirsten S., de Ridder, Maria A.J., Hokken-Koelega, Anita C.S.

“…In order to identify children at risk for excess adiposity, it is important to determine body composition longitudinally throughout childhood. However, most…”
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Gastrointestinal distribution of the prodrug loperamide oxide and its active drug loperamide in the dog by Van Beijsterveldt, L E, Geerts, R J, Wuyts, K, Woestenborghs, R J, Meuldermans, W E, Heykants, J J

“…Loperamide oxide is a prodrug of the effective antidiarrheal loperamide. Administration of this prodrug improves efficacy and tolerability. For better…”
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Longitudinal body composition assessment in healthy term-born infants until 2 years of age using ADP and DXA with vacuum cushion by de Fluiter, Kirsten S., van Beijsterveldt, Inge A.L.P., Goedegebuure, Wesley J., Breij, Laura M., Spaans, Alexander M. J., Acton, Dennis, Hokken-Koelega, Anita C. S.

“…Objectives Accelerated gain in fat mass (FM) in early life increases the risk for adult diseases. Longitudinal data on infant body composition are crucial for…”
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