Search Results - "VALLADEAU, Jenny"

Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods by Bayerl, Felix, Bejarano, David A, Bertacchi, Giulia, Doffin, Anne-Claire, Gobbini, Elisa, Hubert, Margaux, Li, Lijian, Meiser, Philippa, Pedde, Anna-Marie, Posch, Wilfried, Rupp, Luise, Schlitzer, Andreas, Schmitz, Marc, Schraml, Barbara U, Uderhardt, Stefan, Valladeau-Guilemond, Jenny, Wilflingseder, Doris, Zaderer, Viktoria, Böttcher, Jan P

“…This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype…”
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Cold Tumors: A Therapeutic Challenge for Immunotherapy by Bonaventura, Paola, Shekarian, Tala, Alcazer, Vincent, Valladeau-Guilemond, Jenny, Valsesia-Wittmann, Sandrine, Amigorena, Sebastian, Caux, Christophe, Depil, Stéphane

“…Therapeutic monoclonal antibodies targeting immune checkpoints (ICPs) have changed the treatment landscape of many tumors. However, response rate remains…”
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Human natural killer cells promote cross‐presentation of tumor cell‐derived antigens by dendritic cells by Deauvieau, Florence, Ollion, Vincent, Doffin, Anne‐Claire, Achard, Carole, Fonteneau, Jean‐François, Verronese, Estelle, Durand, Isabelle, Ghittoni, Raffaella, Marvel, Jacqueline, Dezutter‐Dambuyant, Colette, Walzer, Thierry, Vie, Henri, Perrot, Ivan, Goutagny, Nadège, Caux, Christophe, Valladeau‐Guilemond, Jenny

“…Dendritic cells (DCs) cross‐present antigen (Ag) to initiate T‐cell immunity against most infections and tumors. Natural killer (NK) cells are innate cytolytic…”
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Characterization of resident and migratory dendritic cells in human lymph nodes by Segura, Elodie, Valladeau-Guilemond, Jenny, Donnadieu, Marie-Hélène, Sastre-Garau, Xavier, Soumelis, Vassili, Amigorena, Sebastian

“…Dendritic cells (DCs) initiate adaptive immune responses in lymph nodes (LNs). In mice, LN DCs can be divided into resident and tissue-derived populations, the…”
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Human Langerhans Cells Express a Specific TLR Profile and Differentially Respond to Viruses and Gram-Positive Bacteria by Flacher, Vincent, Bouschbacher, Marielle, Verronese, Estelle, Massacrier, Catherine, Sisirak, Vanja, Berthier-Vergnes, Odile, de Saint-Vis, Blandine, Caux, Christophe, Dezutter-Dambuyant, Colette, Lebecque, Serge, Valladeau, Jenny

“…Dendritic cells (DC) are APCs essential for the development of primary immune responses. In pluristratified epithelia, Langerhans cells (LC) are a critical…”
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Type 1 conventional dendritic cells and interferons are required for spontaneous CD4+ and CD8+ T‐cell protective responses to breast cancer by Mattiuz, Raphaël, Brousse, Carine, Ambrosini, Marc, Cancel, Jean‐Charles, Bessou, Gilles, Mussard, Julie, Sanlaville, Amélien, Caux, Christophe, Bendriss‐Vermare, Nathalie, Valladeau‐Guilemond, Jenny, Dalod, Marc, Crozat, Karine

“…Objectives To better understand how immune responses may be harnessed against breast cancer, we investigated which immune cell types and signalling pathways…”
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BDCA1+ cDC2s, BDCA2+ pDCs and BDCA3+ cDC1s reveal distinct pathophysiologic features and impact on clinical outcomes in melanoma patients by Sosa Cuevas, Eleonora, Ouaguia, Laurissa, Mouret, Stephane, Charles, Julie, Fraipont, Florence, Manches, Olivier, Valladeau‐Guilemond, Jenny, Bendriss‐Vermare, Nathalie, Chaperot, Laurence, Aspord, Caroline

“…Objectives Dendritic cells play a pivotal but still enigmatic role in the control of tumor development. Composed of specialised subsets (cDC1s, cDC2s, pDCs),…”
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Diversification of circulating and tumor‐infiltrating plasmacytoid DCs towards the P3 (CD80+ PDL1−)‐pDC subset negatively correlated with clinical outcomes in melanoma patients by Sosa Cuevas, Eleonora, Bendriss‐Vermare, Nathalie, Mouret, Stephane, De Fraipont, Florence, Charles, Julie, Valladeau‐Guilemond, Jenny, Chaperot, Laurence, Aspord, Caroline

“…Objectives Plasmacytoid DCs (pDCs) play a critical yet enigmatic role in antitumor immunity through their pleiotropic immunomodulatory functions. Despite proof…”
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In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas by Bell, D, Chomarat, P, Broyles, D, Netto, G, Harb, G M, Lebecque, S, Valladeau, J, Davoust, J, Palucka, K A, Banchereau, J

“…We have analyzed the presence of immature and mature dendritic cells (DCs) within adenocarcinoma of the breast using immunohistochemistry. Immature DCs were…”
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Unique CLR expression patterns on circulating and tumor-infiltrating DC subsets correlated with clinical outcome in melanoma patients by Sosa Cuevas, Eleonora, Valladeau-Guilemond, Jenny, Mouret, Stephane, Roubinet, Benoît, de Fraipont, Florence, Landemarre, Ludovic, Charles, Julie, Bendriss-Vermare, Nathalie, Chaperot, Laurence, Aspord, Caroline

“…Subversion of immunity by tumors is a crucial step for their development. Dendritic cells (DCs) are strategic immune cells that orchestrate anti-tumor immune…”
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Structural Studies of Langerin and Birbeck Granule: A Macromolecular Organization Model by Thépaut, Michel, Valladeau, Jenny, Nurisso, Alessandra, Kahn, Richard, Arnou, Bertrand, Vivès, Corinne, Saeland, Sem, Ebel, Christine, Monnier, Carine, Dezutter-Dambuyant, Colette, Imberty, Anne, Fieschi, Franck

“…Dendritic cells, a sentinel immunity cell lineage, include different cell subsets that express various C-type lectins. For example, epidermal Langerhans cells…”
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Expression of TAM-R in Human Immune Cells and Unique Regulatory Function of MerTK in IL-10 Production by Tolerogenic DC by Giroud, Paul, Renaudineau, Sarah, Gudefin, Laura, Calcei, Alexandre, Menguy, Thierry, Rozan, Caroline, Mizrahi, Jacques, Caux, Christophe, Duong, Vanessa, Valladeau-Guilemond, Jenny

“…Tumor-infiltrating myeloid cells are a key component of the immune infiltrate often correlated with a poor prognosis due to their capacities to sustain an…”
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Hepatitis B virus exploits C‐type lectin receptors to hijack cDC1s, cDC2s and pDCs by Ouaguia, Laurissa, Dufeu‐Duchesne, Tania, Leroy, Vincent, Decaens, Thomas, Reiser, Jean‐Baptiste, Sosa Cuevas, Eleonora, Durantel, David, Valladeau‐Guilemond, Jenny, Bendriss‐Vermare, Nathalie, Chaperot, Laurence, Aspord, Caroline

“…Objectives C‐type lectin receptors (CLRs) are key receptors used by DCs to orchestrate responses to pathogens. During infections, the glycan–lectin…”
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Differentiation of Langerhans cells in Langerhans cell histiocytosis by Geissmann, Frederic, Lepelletier, Yves, Fraitag, Sylvie, Valladeau, Jenny, Bodemer, Christine, Debré, Marianne, Leborgne, Michelle, Saeland, Sem, Brousse, Nicole

“…Langerhans cell histiocytosis (LCH) consists of lesions composed of cells with a dendritic Langerhans cell (LC) phenotype. The clinical course of LCH ranges…”
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Circulating and Hepatic BDCA1+, BDCA2+, and BDCA3+ Dendritic Cells Are Differentially Subverted in Patients With Chronic HBV Infection by Ouaguia, Laurissa, Leroy, Vincent, Dufeu-Duchesne, Tania, Durantel, David, Decaens, Thomas, Hubert, Margaux, Valladeau-Guilemond, Jenny, Bendriss-Vermare, Nathalie, Chaperot, Laurence, Aspord, Caroline

“…Chronic hepatitis B virus (HBV) infection is a major health burden potentially evolving toward cirrhosis and hepatocellular carcinoma. HBV physiopathology is…”
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A CD1a+/CD11c+ Subset of Human Blood Dendritic Cells Is a Direct Precursor of Langerhans Cells by Ito, Tomoki, Inaba, Muneo, Inaba, Kayo, Toki, Junko, Sogo, Shinji, Iguchi, Tomoko, Adachi, Yasushi, Yamaguchi, Kazuyuki, Amakawa, Ryuichi, Valladeau, Jenny, Saeland, Sem, Fukuhara, Shirou, Ikehara, Susumu

“…Based on the relative expression of CD11c and CD1a, we have identified three fractions of dendritic cells (DCs) in human peripheral blood, including a direct…”
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The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface by Valladeau, Jenny, Duvert‐Frances, Valérie, Pin, Jean‐Jacques, Dezutter‐Dambuyant, Colette, Vincent, Claude, Massacrier, Catherine, Vincent, Jérôme, Yoneda, Kozo, Banchereau, Jacques, Caux, Christophe, Davoust, Jean, Saeland, Sem

“…We generated monoclonal antibody (mAb) DCGM4 by immunization with human dendritic cells (DC) from CD34+ progenitors cultured with granulocyte‐macrophage…”
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APCs Express DCIR, a Novel C-Type Lectin Surface Receptor Containing an Immunoreceptor Tyrosine-Based Inhibitory Motif by Bates, Elizabeth E. M, Fournier, Nathalie, Garcia, Eric, Valladeau, Jenny, Durand, Isabelle, Pin, Jean-Jacques, Zurawski, Sandra M, Patel, Sejal, Abrams, John S, Lebecque, Serge, Garrone, Pierre, Saeland, Sem

“…We have identified a novel member of the calcium-dependent (C-type) lectin family. This molecule, designated DCIR (for dendritic cell (DC) immunoreceptor), is…”
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Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectin by de Saint-Vis, Blandine, Bouchet, Caroline, Gautier, Grégory, Valladeau, Jenny, Caux, Christophe, Garrone, Pierre

“…Eph receptor tyrosine kinases and their ligands, the ephrins, have been primarily described in the nervous system for their roles in axon guidance,…”
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691 Identification of shared tumor epitopes from endogenous retroviruses inducing high avidity cytotoxic T cells for cancer immunotherapy by Bonaventura, Paola, Alcazer, Vincent, Mutez, Virginie, Tonon, Laurie, Martin, Juliette, Chuvin, Nicolas, Boulos, Rasha, Estornes, Yann, Valladeau-Guilemond, Jenny, Viari, Alain, Caux, Christophe, Depil, Stephane

“…BackgroundHuman endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of T cell epitopesMethodsUsing TCGA…”
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